Vaginal cancer epidemiology and demographics: Difference between revisions

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==Epidemiology and Demographics==
==Epidemiology and Demographics==
* Carcinomas of the vagina are uncommon tumors comprising about 1% of the cancers that arise in the female genital system.
* Carcinomas of the vagina are uncommon tumors comprising about 1% of the cancers that arise in the female genital system<ref name="pmid25476235">{{cite journal |vauthors=Gadducci A, Fabrini MG, Lanfredini N, Sergiampietri C |title=Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors |journal=Crit. Rev. Oncol. Hematol. |volume=93 |issue=3 |pages=211–24 |date=March 2015 |pmid=25476235 |doi=10.1016/j.critrevonc.2014.09.002 |url=}}</ref>.
* Estimated new cases and deaths from vaginal (and other female genital) cancer in the United States in 2015:
* Estimated new cases and deaths from vaginal (and other female genital) cancer in the United States in 2015:
:* New cases: 4,070.
:* New cases: 4,070.

Revision as of 16:53, 21 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

In 2015, the incidence of vaginal cancer is approximately 2-3 per 100,000 individuals with a death number of 910.

Epidemiology and Demographics

  • Carcinomas of the vagina are uncommon tumors comprising about 1% of the cancers that arise in the female genital system[1].
  • Estimated new cases and deaths from vaginal (and other female genital) cancer in the United States in 2015:
  • New cases: 4,070.
  • Deaths: 910.
  • Estimated new cases and deaths from vaginal (and other female genital) cancer in the United States in 2008:
  • New cases: 2,210.
  • Deaths: 760.
  • 1 in 100,000 women will be diagnosed with in situ or invasive vaginal cancer[2].
  • Most cases of vaginal cancer are likely mediated by human papillomavirus (HPV) infection, as with cervical cancer [8].
  • Vaginal cancer has the same risk factors as cervical neoplasia: multiple lifetime sexual partners, early age at first intercourse, and being a current smoker [9,10].
  • There is evidence that some high-grade vulvar and vaginal intraepithelial neoplasia are monoclonal lesions derived from high-grade or malignant cervical disease [11].

References

  1. Gadducci A, Fabrini MG, Lanfredini N, Sergiampietri C (March 2015). "Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors". Crit. Rev. Oncol. Hematol. 93 (3): 211–24. doi:10.1016/j.critrevonc.2014.09.002. PMID 25476235.
  2. Shah CA, Goff BA, Lowe K, Peters WA, Li CI (May 2009). "Factors affecting risk of mortality in women with vaginal cancer". Obstet Gynecol. 113 (5): 1038–45. doi:10.1097/AOG.0b013e31819fe844. PMC 2746762. PMID 19384118.