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{{Upper gastrointestinal bleeding}}
{{Upper gastrointestinal bleeding}}
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==Epidemiology and Demographics==
About 75% of patients presenting to the emergency room with GI bleeding have an upper source {{ref|1}}. The diagnosis is easier when the patient has hematemesis. In the absence of hematemesis, 40% to 50% of patients in the emergency room with GI bleeding have an upper source{{ref|2}} {{ref|3}} {{ref|4}}. Determining whether a patient truly has an upper GI bleed versus [[lower gastrointestinal bleeding]] is difficult.
 
Whiting studied a cohort of 325 patients and found the odds ratios for the strongest predictors were: black stool, 16.6 (95% confidence interval [CI], 7.7-35.7); age < 50 years, 8.4 (95% CI, 3.2-22.1); and blood urea nitrogen/creatinine ratio 30 or more, 10.0 (95% CI, 4.0-25.6){{ref|2}} . Seven (5%) of 151 with none of these factors had an upper GI tract bleed, versus 63 (93%) of 68 with 2 or 3 factors. Ernst found similar results{{ref|1}}.
 
==Overview==
==Overview==
About 75% of patients presenting to the emergency room with upper gastrointestinal bleeding (UGIB) have an upper source. The diagnosis is easier when the patient has hematemesis. In the absence of hematemesis, 40% to 50% of patients in the emergency room with GI bleeding have an upper source. The incidence of acute UGIB is approximately 50 to 100 per 100,000 individuals worldwide. Patients of all age groups may develop upper gastrointestinal bleeding. Males are more commonly affected by UGIB than females.


==Epidemiology and Demographics==
==Epidemiology==
===Incidence===
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The incidence of acute upper gastrointestinal bleeding (UGIB) is approximately 50 to 100 per 100,000 individuals worldwide.<ref name="pmid22468077">{{cite journal |vauthors=El-Tawil AM |title=Trends on gastrointestinal bleeding and mortality: where are we standing? |journal=World J. Gastroenterol. |volume=18 |issue=11 |pages=1154–8 |year=2012 |pmid=22468077 |pmc=3309903 |doi=10.3748/wjg.v18.i11.1154 |url=}}</ref><ref name="pmid18346679">{{cite journal |vauthors=van Leerdam ME |title=Epidemiology of acute upper gastrointestinal bleeding |journal=Best Pract Res Clin Gastroenterol |volume=22 |issue=2 |pages=209–24 |year=2008 |pmid=18346679 |doi=10.1016/j.bpg.2007.10.011 |url=}}</ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*Approximately 100,000 patients are admitted to US hospitals for therapy for UGIB.


===Prevalence===
=== Prevalence ===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
* The prevalence of UGIB is almost the same as incidence, as it is a medical emergency and is not a chronic disease.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
 
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].


===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Patients of all age groups may develop upper gastrointestinal bleeding.
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*The population with UGIB has become progressively older, with a concurrent increase in significant comorbidities that increase mortality.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*Mortality increases with older age (>60 y), in both males and females.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].
 
===Race===
===Race===
*There is no racial predilection to [disease name].
There is no racial predilection to upper gastrointestinal bleeding.
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
===Gender===
===Gender===
*[Disease name] affects men and women equally.
*Upper gastrointestinal bleeding is more common in males than females.
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
*The males to female ratio is approximately 2 to 1.
===Region===
*The majority of [disease name] cases are reported in [geographical region].
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
 
===Developed Countries===
 
===Developing Countries===
 
 


==References==
==References==

Latest revision as of 22:02, 13 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

About 75% of patients presenting to the emergency room with upper gastrointestinal bleeding (UGIB) have an upper source. The diagnosis is easier when the patient has hematemesis. In the absence of hematemesis, 40% to 50% of patients in the emergency room with GI bleeding have an upper source. The incidence of acute UGIB is approximately 50 to 100 per 100,000 individuals worldwide. Patients of all age groups may develop upper gastrointestinal bleeding. Males are more commonly affected by UGIB than females.

Epidemiology

Incidence

  • The incidence of acute upper gastrointestinal bleeding (UGIB) is approximately 50 to 100 per 100,000 individuals worldwide.[1][2]
  • Approximately 100,000 patients are admitted to US hospitals for therapy for UGIB.

Prevalence

  • The prevalence of UGIB is almost the same as incidence, as it is a medical emergency and is not a chronic disease.

Age

  • Patients of all age groups may develop upper gastrointestinal bleeding.
  • The population with UGIB has become progressively older, with a concurrent increase in significant comorbidities that increase mortality.
  • Mortality increases with older age (>60 y), in both males and females.

Race

There is no racial predilection to upper gastrointestinal bleeding.

Gender

  • Upper gastrointestinal bleeding is more common in males than females.
  • The males to female ratio is approximately 2 to 1.

References

  1. El-Tawil AM (2012). "Trends on gastrointestinal bleeding and mortality: where are we standing?". World J. Gastroenterol. 18 (11): 1154–8. doi:10.3748/wjg.v18.i11.1154. PMC 3309903. PMID 22468077.
  2. van Leerdam ME (2008). "Epidemiology of acute upper gastrointestinal bleeding". Best Pract Res Clin Gastroenterol. 22 (2): 209–24. doi:10.1016/j.bpg.2007.10.011. PMID 18346679.


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