Turner syndrome interventions: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
 
Line 5: Line 5:
==Overview==
==Overview==


Psycosocial interventions aimed at treating visual spatial and executive function deficits along with in vitro fertilization (for infertility) are the interventions commonly used in Turner syndrome.
[[Psychosocial]] interventions aimed at treating visual spatial and executive function deficits along with [[in-vitro fertilization]] (for [[infertility]]) are the interventions commonly used in [[Turner syndrome]].


==Psychosocial interventions==
==Psychosocial interventions==


*After assessing a patient’s strengths and weaknesses, an individualized syndrome specific approach should be followed which deals with the following issues: <ref name="pmid17562588">{{cite journal| author=Kesler SR| title=Turner syndrome. | journal=Child Adolesc Psychiatr Clin N Am | year= 2007 | volume= 16 | issue= 3 | pages= 709-22 | pmid=17562588 | doi=10.1016/j.chc.2007.02.004 | pmc=2023872 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17562588  }} </ref>
*After assessing a patient’s strengths and weaknesses, an individualized syndrome specific approach should be followed which deals with the following issues: <ref name="pmid17562588">{{cite journal| author=Kesler SR| title=Turner syndrome. | journal=Child Adolesc Psychiatr Clin N Am | year= 2007 | volume= 16 | issue= 3 | pages= 709-22 | pmid=17562588 | doi=10.1016/j.chc.2007.02.004 | pmc=2023872 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17562588  }} </ref>
**Dealing with chronic issues such as cardiovascular disease, hearing loss and infertility with adaptive skills.
**Dealing with chronic issues such as [[cardiovascular]] disease, hearing loss and [[infertility]] with adaptive skills.
**Individual and group social skills training which will help the patient in self-monitoring and recognition one’s facial/body habitus.  
**Individual and group social skills training which will help the patient in self-monitoring and recognition one’s facial/body habitus.  
**Stress management to decrease anxiety and mood disturbances.
**Stress management to decrease [[anxiety]] and mood disturbances.
**Efforts to improve self esteem and self perception.
**Efforts to improve self esteem and self perception.
**Strategies to compensate for cognitive weakness- using self talk to pay attention, focusing on one task, instead of several tasks at one time, paraphrasing what others said to ensure comprehension.  
**Strategies to compensate for [[cognitive]] weakness- using self talk to pay attention, focusing on one task, instead of several tasks at one time, paraphrasing what others said to ensure comprehension.  
**ADHD medication, use of verbal mnemonics, classrooms modeled to provide occupational and physical training may help in academic achievement<ref name="pmid29344338">{{cite journal| author=Shankar RK, Backeljauw PF| title=Current best practice in the management of Turner syndrome. | journal=Ther Adv Endocrinol Metab | year= 2018 | volume= 9 | issue= 1 | pages= 33-40 | pmid=29344338 | doi=10.1177/2042018817746291 | pmc=5761955 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29344338  }} </ref>
**[[ADHD]] medication, use of verbal mnemonics, classrooms modeled to provide occupational and physical training may help in academic achievement<ref name="pmid29344338">{{cite journal| author=Shankar RK, Backeljauw PF| title=Current best practice in the management of Turner syndrome. | journal=Ther Adv Endocrinol Metab | year= 2018 | volume= 9 | issue= 1 | pages= 33-40 | pmid=29344338 | doi=10.1177/2042018817746291 | pmc=5761955 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29344338  }} </ref>
*These strategies are aimed for compensating the supposed deficits in the fronto-parietal pathways that are responsible for the disconnect between visuospatial and executive functioning during complicated tasks.  
*These strategies are aimed for compensating the supposed deficits in the [[fronto-parietal pathways]] that are responsible for the disconnect between [[visuospatial]] and executive functioning during complicated tasks.  
*Pediatricians may also refer to Turner syndrome support groups or arrange for meetings with parents of Turner syndrome patients. <ref name="pmid12612263">{{cite journal| author=Frías JL, Davenport ML, Committee on Genetics and Section on Endocrinology| title=Health supervision for children with Turner syndrome. | journal=Pediatrics | year= 2003 | volume= 111 | issue= 3 | pages= 692-702 | pmid=12612263 | doi=10.1542/peds.111.3.692 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12612263  }} </ref>
*[[Pediatricians]] may also refer to [[Turner syndrome]] support groups or arrange for meetings with parents of Turner syndrome patients. <ref name="pmid12612263">{{cite journal| author=Frías JL, Davenport ML, Committee on Genetics and Section on Endocrinology| title=Health supervision for children with Turner syndrome. | journal=Pediatrics | year= 2003 | volume= 111 | issue= 3 | pages= 692-702 | pmid=12612263 | doi=10.1542/peds.111.3.692 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12612263  }} </ref>


==Treatment of Infertility==
==Treatment of Infertility==


*Treatment approaches depend on the presence or absence of an adequate ovarian reserve.  
*Treatment approaches depend on the presence or absence of an adequate [[ovarian reserve]].  
**This is determined by serum gonadotrophin releasing hormone, serum LH levels, serum FSH levels, biopsy of ovarian tissue (to evaluate ovarian karyotype) and serum anti Mullerian hormone levels.  
**This is determined by [[serum gonadotrophin releasing hormone]], [[serum LH]] levels, [[serum FSH]] levels, [[biopsy]] of [[ovarian]] tissue (to evaluate ovarian [[karyotype]]) and [[serum anti Mullerian hormone]] levels.  
*In vitro fertilization with donor oocytes and embryo transfer is the most common treatment modality.  
*[[In-vitro fertilization]] with donor [[oocytes]] and [[embryo]] transfer is the most common treatment modality.  
*Ovarian tissue cryobanking and immature oocyte collection followed by fertilization of matured oocytes is another promising approach. <ref name="pmid22218436">{{cite journal| author=Collett-Solberg PF, Gallicchio CT, Coelho SC, Siqueira RA, Alves ST, Guimarães MM| title=Endocrine diseases, perspectives and care in Turner syndrome. | journal=Arq Bras Endocrinol Metabol | year= 2011 | volume= 55 | issue= 8 | pages= 550-8 | pmid=22218436 | doi=10.1590/s0004-27302011000800008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22218436  }} </ref>
*Ovarian tissue [[cryobanking]] and immature [[oocyte]] collection followed by [[fertilization]] of matured oocytes is another promising approach. <ref name="pmid22218436">{{cite journal| author=Collett-Solberg PF, Gallicchio CT, Coelho SC, Siqueira RA, Alves ST, Guimarães MM| title=Endocrine diseases, perspectives and care in Turner syndrome. | journal=Arq Bras Endocrinol Metabol | year= 2011 | volume= 55 | issue= 8 | pages= 550-8 | pmid=22218436 | doi=10.1590/s0004-27302011000800008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22218436  }} </ref>





Latest revision as of 15:04, 15 September 2020

Turner syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Turner syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Turner syndrome interventions On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Turner syndrome interventions

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Turner syndrome interventions

CDC on Turner syndrome interventions

Turner syndrome interventions in the news

Blogs on Turner syndrome interventions

Directions to Hospitals Treating Turner syndrome

Risk calculators and risk factors for Turner syndrome interventions

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akash Daswaney, M.B.B.S[2]

Overview

Psychosocial interventions aimed at treating visual spatial and executive function deficits along with in-vitro fertilization (for infertility) are the interventions commonly used in Turner syndrome.

Psychosocial interventions

  • After assessing a patient’s strengths and weaknesses, an individualized syndrome specific approach should be followed which deals with the following issues: [1]
    • Dealing with chronic issues such as cardiovascular disease, hearing loss and infertility with adaptive skills.
    • Individual and group social skills training which will help the patient in self-monitoring and recognition one’s facial/body habitus.
    • Stress management to decrease anxiety and mood disturbances.
    • Efforts to improve self esteem and self perception.
    • Strategies to compensate for cognitive weakness- using self talk to pay attention, focusing on one task, instead of several tasks at one time, paraphrasing what others said to ensure comprehension.
    • ADHD medication, use of verbal mnemonics, classrooms modeled to provide occupational and physical training may help in academic achievement[2]
  • These strategies are aimed for compensating the supposed deficits in the fronto-parietal pathways that are responsible for the disconnect between visuospatial and executive functioning during complicated tasks.
  • Pediatricians may also refer to Turner syndrome support groups or arrange for meetings with parents of Turner syndrome patients. [3]

Treatment of Infertility


References

  1. Kesler SR (2007). "Turner syndrome". Child Adolesc Psychiatr Clin N Am. 16 (3): 709–22. doi:10.1016/j.chc.2007.02.004. PMC 2023872. PMID 17562588.
  2. Shankar RK, Backeljauw PF (2018). "Current best practice in the management of Turner syndrome". Ther Adv Endocrinol Metab. 9 (1): 33–40. doi:10.1177/2042018817746291. PMC 5761955. PMID 29344338.
  3. Frías JL, Davenport ML, Committee on Genetics and Section on Endocrinology (2003). "Health supervision for children with Turner syndrome". Pediatrics. 111 (3): 692–702. doi:10.1542/peds.111.3.692. PMID 12612263.
  4. Collett-Solberg PF, Gallicchio CT, Coelho SC, Siqueira RA, Alves ST, Guimarães MM (2011). "Endocrine diseases, perspectives and care in Turner syndrome". Arq Bras Endocrinol Metabol. 55 (8): 550–8. doi:10.1590/s0004-27302011000800008. PMID 22218436.

Template:WH Template:WS