Tongue cancer CT: Difference between revisions

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{{Tongue cancer}}
{{Tongue cancer}}
{{CMG}}{{AE}}{{Simrat}}
{{CMG}}{{AE}} {{Simrat}} {{RAK}}
==Overview==
==Overview==
Head and neck [[CT scan]] may be helpful in the diagnosis of tongue cancer. Findings on CT scan suggestive of tongue cancer include [[soft tissue]] attenuation of [[lesions]], bony erosions, and increased attenuation of involved nodes.<ref name="radio">  Sqamous cell carcinoma of the tongue. Radiopedia(2015) http://radiopaedia.org/articles/squamous-cell-carcinoma-of-the-tongue Accessed on November 17, 2015</ref>
Head and neck [[CT scan]] may be helpful in the diagnosis of tongue cancer. Findings on CT scan suggestive of tongue cancer include [[soft tissue]] attenuation of [[lesions]], bony erosions, and increased attenuation of involved nodes.
==CT==
==CT==
*CT is the most commonly used modality for assessment of tongue [[squamous cell carcinoma]], able to both locally stage the [[tumor]] and assess for nodal metastases.
*CT is the most commonly used modality for assessment of tongue [[squamous cell carcinoma]]
*Lesions typically appear of soft tissue attenuation, usually a little more attenuating than normal tongue musculature (on account of the [[keratin]]) and enhance following contrast administration.
*Lesions typically appear more attenuating than normal tongue musculature (on account of the [[keratin]]) and enhance following contrast administration.
*Both algorhythm thin section CT is the most sensitive modality for assessing early bony erosion.
*Non-contrast scans of the neck may demonstrate increased attenuation of involved nodes due to keratin production by tumor deposits.<ref name="pmid12917122">{{cite journal| author=Hayashi T, Tanaka R, Taira S, Koyama J, Katsura K, Kobayashi F| title=Non-contrast-enhanced CT findings of high attenuation within metastatic cervical lymph nodes in patients with stage I or II tongue carcinoma during a follow-up period. | journal=AJNR Am J Neuroradiol | year= 2003 | volume= 24 | issue= 7 | pages= 1330-3 | pmid=12917122 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12917122  }} </ref>
*Non-contrast scans of the neck may demonstrate increased attenuation of involved nodes due to keratin production by tumor deposits.<ref name="radio"> Sqamous cell carcinoma of the tongue. Radiopedia(2015) http://radiopaedia.org/articles/squamous-cell-carcinoma-of-the-tongue Accessed on November 17, 2015</ref>
*CT is better for the evaluation of bone destruction.
*CT is the modality of choice to evaluate the patient's nodal status. The evaluation of nodal size, number, location, contour and [[necrosis]] is helpful in staging. Tongue cancer may be difficult to pick up on CT due to its imaging characteristics, unless the tumor leads to deformity of the extrinsic tongue musculature or the anatomy of the floor of mouth or tongue base.  
*Assessment of cartilage invasion.<ref name="pmid22984188">{{cite journal| author=Kuno H, Onaya H, Iwata R, Kobayashi T, Fujii S, Hayashi R et al.| title=Evaluation of cartilage invasion by laryngeal and hypopharyngeal squamous cell carcinoma with dual-energy CT. | journal=Radiology | year= 2012 | volume= 265 | issue= 2 | pages= 488-96 | pmid=22984188 | doi=10.1148/radiol.12111719 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22984188  }}</ref>  
*Detection of extracapsular spread of tumor.  
*Pathologic lymph nodes are 10 to 11 mm and contains central necrosis. Size criteria based on measurement of minimal axial diameter are considered the most accurate and effective.<ref name="pmid2217772">{{cite journal| author=van den Brekel MW, Stel HV, Castelijns JA, Nauta JJ, van der Waal I, Valk J et al.| title=Cervical lymph node metastasis: assessment of radiologic criteria. | journal=Radiology | year= 1990 | volume= 177 | issue= 2 | pages= 379-84 | pmid=2217772 | doi=10.1148/radiology.177.2.2217772 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2217772  }}</ref> 
*Pathological lymph nodes show: loss of normal fatty hilum, increased or heterogeneous contrast enhancement, lymph node clustering.<ref name="pmid9530307">{{cite journal| author=Curtin HD, Ishwaran H, Mancuso AA, Dalley RW, Caudry DJ, McNeil BJ| title=Comparison of CT and MR imaging in staging of neck metastases. | journal=Radiology | year= 1998 | volume= 207 | issue= 1 | pages= 123-30 | pmid=9530307 | doi=10.1148/radiology.207.1.9530307 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9530307  }}</ref> 
*Sensitivity is 83% and specificity is 83%.<ref name="pmid9046281">{{cite journal| author=Merritt RM, Williams MF, James TH, Porubsky ES| title=Detection of cervical metastasis. A meta-analysis comparing computed tomography with physical examination. | journal=Arch Otolaryngol Head Neck Surg | year= 1997 | volume= 123 | issue= 2 | pages= 149-52 | pmid=9046281 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9046281  }}</ref> 
 
== PET-CT scan ==
* PET appears to be as sensitive and specific as CT and MRI in detecting primary head and neck tumors.<ref name="pmid21674668">{{cite journal| author=Rudmik L, Lau HY, Matthews TW, Bosch JD, Kloiber R, Molnar CP et al.| title=Clinical utility of PET/CT in the evaluation of head and neck squamous cell carcinoma with an unknown primary: a prospective clinical trial. | journal=Head Neck | year= 2011 | volume= 33 | issue= 7 | pages= 935-40 | pmid=21674668 | doi=10.1002/hed.21566 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21674668  }}</ref>
* PET is superior to both CT and MRI for detecting regional nodal metastases, as well as distant metastases and second primary tumors.<ref name="pmid24010911">{{cite journal| author=Escott EJ| title=Role of positron emission tomography/computed tomography (PET/CT) in head and neck cancer. | journal=Radiol Clin North Am | year= 2013 | volume= 51 | issue= 5 | pages= 881-93 | pmid=24010911 | doi=10.1016/j.rcl.2013.05.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24010911  }}</ref>
* False negatives of PET may be seen in lymph nodes less than 5 mm, necrotic or cystic lymph nodes, and tumors of low metabolic activity. [56]
* PET/CT is sensitive and superior for evaluation of deep lesions. [78]
<gallery>
<gallery>
Axial bone window (2).jpeg|CT of squamous cell carcinoma of the tongue showing axial bone window <ref name="radio1">Image courtesy of Dr. Bruno Di Muzio [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/squamous-cell-carcinoma-of-the-tongue-1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>
Axial bone window (2).jpeg|CT of squamous cell carcinoma of the tongue showing axial bone window <ref name="radio1">Image courtesy of Dr. Bruno Di Muzio [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/squamous-cell-carcinoma-of-the-tongue-1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>
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[[Category:Otolaryngology]]
[[Category:Otolaryngology]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gastroenterology]]
[[Category:Surgery]]
[[Category:Otolaryngology]]

Latest revision as of 18:31, 6 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [3] Roukoz A. Karam, M.D.[4]

Overview

Head and neck CT scan may be helpful in the diagnosis of tongue cancer. Findings on CT scan suggestive of tongue cancer include soft tissue attenuation of lesions, bony erosions, and increased attenuation of involved nodes.

CT

  • CT is the most commonly used modality for assessment of tongue squamous cell carcinoma
  • Lesions typically appear more attenuating than normal tongue musculature (on account of the keratin) and enhance following contrast administration.
  • Non-contrast scans of the neck may demonstrate increased attenuation of involved nodes due to keratin production by tumor deposits.[1]
  • CT is better for the evaluation of bone destruction.
  • Assessment of cartilage invasion.[2]
  • Detection of extracapsular spread of tumor. 
  • Pathologic lymph nodes are 10 to 11 mm and contains central necrosis. Size criteria based on measurement of minimal axial diameter are considered the most accurate and effective.[3]
  • Pathological lymph nodes show: loss of normal fatty hilum, increased or heterogeneous contrast enhancement, lymph node clustering.[4]
  • Sensitivity is 83% and specificity is 83%.[5] 

PET-CT scan

  • PET appears to be as sensitive and specific as CT and MRI in detecting primary head and neck tumors.[6]
  • PET is superior to both CT and MRI for detecting regional nodal metastases, as well as distant metastases and second primary tumors.[7]
  • False negatives of PET may be seen in lymph nodes less than 5 mm, necrotic or cystic lymph nodes, and tumors of low metabolic activity. [56]
  • PET/CT is sensitive and superior for evaluation of deep lesions. [78]

References

  1. Hayashi T, Tanaka R, Taira S, Koyama J, Katsura K, Kobayashi F (2003). "Non-contrast-enhanced CT findings of high attenuation within metastatic cervical lymph nodes in patients with stage I or II tongue carcinoma during a follow-up period". AJNR Am J Neuroradiol. 24 (7): 1330–3. PMID 12917122.
  2. Kuno H, Onaya H, Iwata R, Kobayashi T, Fujii S, Hayashi R; et al. (2012). "Evaluation of cartilage invasion by laryngeal and hypopharyngeal squamous cell carcinoma with dual-energy CT". Radiology. 265 (2): 488–96. doi:10.1148/radiol.12111719. PMID 22984188.
  3. van den Brekel MW, Stel HV, Castelijns JA, Nauta JJ, van der Waal I, Valk J; et al. (1990). "Cervical lymph node metastasis: assessment of radiologic criteria". Radiology. 177 (2): 379–84. doi:10.1148/radiology.177.2.2217772. PMID 2217772.
  4. Curtin HD, Ishwaran H, Mancuso AA, Dalley RW, Caudry DJ, McNeil BJ (1998). "Comparison of CT and MR imaging in staging of neck metastases". Radiology. 207 (1): 123–30. doi:10.1148/radiology.207.1.9530307. PMID 9530307.
  5. Merritt RM, Williams MF, James TH, Porubsky ES (1997). "Detection of cervical metastasis. A meta-analysis comparing computed tomography with physical examination". Arch Otolaryngol Head Neck Surg. 123 (2): 149–52. PMID 9046281.
  6. Rudmik L, Lau HY, Matthews TW, Bosch JD, Kloiber R, Molnar CP; et al. (2011). "Clinical utility of PET/CT in the evaluation of head and neck squamous cell carcinoma with an unknown primary: a prospective clinical trial". Head Neck. 33 (7): 935–40. doi:10.1002/hed.21566. PMID 21674668.
  7. Escott EJ (2013). "Role of positron emission tomography/computed tomography (PET/CT) in head and neck cancer". Radiol Clin North Am. 51 (5): 881–93. doi:10.1016/j.rcl.2013.05.002. PMID 24010911.
  8. 8.0 8.1 Image courtesy of Dr. Bruno Di Muzio Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC

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