Squamous cell carcinoma of the lung epidemiology and demographics: Difference between revisions

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{{Squamous cell carcinoma of the lung}}
{{Squamous cell carcinoma of the lung}}
{{CMG}}; {{AE}} {{SC}}
{{CMG}}; {{AE}} {{SC}} {{MV}}
==Overview==
==Overview==
Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers. It is the second most commonly encountered [[lung cancer]] after [[Adenocarcinoma of the lung|lung adenocarcinoma]]. Squamous cell carcinoma of the lung accounts for approximately 27% of all [[cancer]] deaths. The [[incidence]] of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] increases with age; the [[median]] age at [[diagnosis]] is approximately 70 years (usually ranging from 65 to 74 years). Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Black race has a higher [[incidence]] of squamous cell lung carcinoma compared with White race.
==Epidemiology and Demographics==
==Epidemiology and Demographics==
Squamous cell carcinoma accounts for ~30-35% of all lung cancers and in most instances are due to heavy smoking. Historically it was the most common type of lung cancer but in many countries has gradually declined over the past four decades with a rise in adenocarcinoma of the lung, which is now the most common in many series 4.


In general, squamous carcinomas are encountered more frequently in male smokers, and adenocarcinoma in female smokers, although these results vary from series to series.  
===Prevalence===
* Squamous cell carcinoma of the lung is the second most common [[Non small cell lung cancer|non-small cell lung cancer]] subtype in the United States.
* It accounts for 30% to 35% of all [[Lung cancer|lung cancers]].
* It accounts for approximately 27% of all cancer deaths.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
*The overall mortality from lung cancer ([[Non small cell lung cancer|NSCLC]] and [[Small cell lung cancer|SCLC]] combined) in the United States in 2018 is 47.14 per 100,000 individuals.<ref>American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.</ref>
 
===Incidence===
* The annual [[incidence]] rate of [[Squamous-cell carcinoma|lung squamous cell carcinoma]] is 14.4 per 100,000 individuals.
* The relative [[incidence]] rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
*The overall incidence of lung cancer ([[NSCLC]] and [[Small cell lung cancer|SCLC]] combined) in the United States in 2018 is 71.629 per 100,000 individuals.<ref>American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.</ref>
 
===Age===
* The incidence of squamous cell carcinoma of the lung increases with age; the [[median]] age at diagnosis is 70 years (usually ranging from 65 to 74 years).<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>
 
===Gender===
*Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1.
===Race===
*Black race has a higher incidence of squamous cell lung carcinoma compared with White race.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>


==References==
==References==
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[[Category:Lung cancer]]
[[Category:Lung cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Pulmonology]]
[[Category:Surgery]]

Latest revision as of 19:39, 17 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]

Overview

Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers. It is the second most commonly encountered lung cancer after lung adenocarcinoma. Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths. The incidence of lung squamous-cell carcinoma increases with age; the median age at diagnosis is approximately 70 years (usually ranging from 65 to 74 years). Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Black race has a higher incidence of squamous cell lung carcinoma compared with White race.

Epidemiology and Demographics

Prevalence

  • Squamous cell carcinoma of the lung is the second most common non-small cell lung cancer subtype in the United States.
  • It accounts for 30% to 35% of all lung cancers.
  • It accounts for approximately 27% of all cancer deaths.[1]
  • The overall mortality from lung cancer (NSCLC and SCLC combined) in the United States in 2018 is 47.14 per 100,000 individuals.[2]

Incidence

  • The annual incidence rate of lung squamous cell carcinoma is 14.4 per 100,000 individuals.
  • The relative incidence rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years.[1]
  • The overall incidence of lung cancer (NSCLC and SCLC combined) in the United States in 2018 is 71.629 per 100,000 individuals.[3]

Age

  • The incidence of squamous cell carcinoma of the lung increases with age; the median age at diagnosis is 70 years (usually ranging from 65 to 74 years).[4]

Gender

  • Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1.

Race

  • Black race has a higher incidence of squamous cell lung carcinoma compared with White race.[1]

References

  1. 1.0 1.1 1.2 Meza R, Meernik C, Jeon J, Cote ML (2015). "Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010". PLoS ONE. 10 (3): e0121323. doi:10.1371/journal.pone.0121323. PMC 4379166. PMID 25822850.
  2. American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.
  3. American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.
  4. Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R (2010). "Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis". J Thorac Oncol. 5 (1): 23–8. doi:10.1097/JTO.0b013e3181c41e8d. PMID 19934774.


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