Short bowel syndrome laboratory findings: Difference between revisions

Jump to navigation Jump to search
No edit summary
m (Bot: Removing from Primary care)
 
(12 intermediate revisions by 2 users not shown)
Line 4: Line 4:


==Overview==
==Overview==
Laboratory findings consistent with the diagnosis of short bowel syndrome include anemia, hypoalbuminemia, low level of vitamins,  
Laboratory findings consistent with the [[diagnosis]] of short bowel syndrome include [[anemia]], [[hypoalbuminemia]], low level of [[Vitamin|vitamins]], [[Mineral|minerals]], and [[Dietary mineral|micronutrients]]. Level of [[Acute phase protein|acute phase reactants]] is high. Abnormal [[liver function tests]] including elevated [[Liver function tests|liver enzymes]] and [[bilirubin]] might be seen. [[Fluid]] and [[Electrolyte disturbance|electrolyte imbalance]] might be present. [[Fecal fat]] test is usually positive.
 
==Laboratory Findings==
==Laboratory Findings==
*Laboratory findings consistent with the diagnosis of short bowel syndrome include:
Laboratory findings consistent with the [[diagnosis]] of short bowel syndrome include:<ref name="Wall2013">{{cite journal|last1=Wall|first1=Elizabeth A.|title=An Overview of Short Bowel Syndrome Management: Adherence, Adaptation, and Practical Recommendations|journal=Journal of the Academy of Nutrition and Dietetics|volume=113|issue=9|year=2013|pages=1200–1208|issn=22122672|doi=10.1016/j.jand.2013.05.001}}</ref><ref name="BoteyAlastrué2017">{{cite journal|last1=Botey|first1=Mireia|last2=Alastrué|first2=Antonio|last3=Haetta|first3=Henrik|last4=Fernández-Llamazares|first4=Jaume|last5=Clavell|first5=Arantxa|last6=Moreno|first6=Pau|title=Long-Term Results of Serial Transverse Enteroplasty with Neovalve Creation for Extreme Short Bowel Syndrome: Report of Two Cases|journal=Case Reports in Gastroenterology|volume=11|issue=1|year=2017|pages=229–240|issn=1662-0631|doi=10.1159/000452734}}</ref><ref name="ThompsonWeseman2011">{{cite journal|last1=Thompson|first1=Jon S.|last2=Weseman|first2=Rebecca|last3=Rochling|first3=Fedja A.|last4=Mercer|first4=David F.|title=Current Management of the Short Bowel Syndrome|journal=Surgical Clinics of North America|volume=91|issue=3|year=2011|pages=493–510|issn=00396109|doi=10.1016/j.suc.2011.02.006}}</ref><ref name="pmid11873098">{{cite journal |vauthors=Sundaram A, Koutkia P, Apovian CM |title=Nutritional management of short bowel syndrome in adults |journal=J. Clin. Gastroenterol. |volume=34 |issue=3 |pages=207–20 |year=2002 |pmid=11873098 |doi= |url=}}</ref><ref name="BechtoldMcClave2014">{{cite journal|last1=Bechtold|first1=Matthew L.|last2=McClave|first2=Stephen A.|last3=Palmer|first3=Lena B.|last4=Nguyen|first4=Douglas L.|last5=Urben|first5=Lindsay M.|last6=Martindale|first6=Robert G.|last7=Hurt|first7=Ryan T.|title=The Pharmacologic Treatment of Short Bowel Syndrome: New Tricks and Novel Agents|journal=Current Gastroenterology Reports|volume=16|issue=7|year=2014|issn=1522-8037|doi=10.1007/s11894-014-0392-2}}</ref><ref name="DiBaiseYoung2004">{{cite journal|last1=DiBaise|first1=John K.|last2=Young|first2=Rosemary J.|last3=Vanderhoof|first3=Jon A.|title=Intestinal Rehabilitation and the Short Bowel Syndrome: Part 1|journal=The American Journal of Gastroenterology|volume=99|issue=7|year=2004|pages=1386–1395|issn=0002-9270|doi=10.1111/j.1572-0241.2004.30345.x}}</ref><ref name="DiBaiseYoung2004">{{cite journal|last1=DiBaise|first1=John K.|last2=Young|first2=Rosemary J.|last3=Vanderhoof|first3=Jon A.|title=Intestinal Rehabilitation and the Short Bowel Syndrome: Part 2|journal=The American Journal of Gastroenterology|volume=99|issue=9|year=2004|pages=1823–1832|issn=0002-9270|doi=10.1111/j.1572-0241.2004.40836.x}}</ref><ref name="KellerPanter2004">{{cite journal|last1=Keller|first1=Jutta|last2=Panter|first2=Heidi|last3=Layer|first3=Peter|title=Management of the short bowel syndrome after extensive small bowel resection|journal=Best Practice & Research Clinical Gastroenterology|volume=18|issue=5|year=2004|pages=977–992|issn=15216918|doi=10.1016/S1521-6918(04)00060-5}}</ref><ref name="Tappenden2014">{{cite journal|last1=Tappenden|first1=Kelly A.|title=Pathophysiology of Short Bowel Syndrome|journal=Journal of Parenteral and Enteral Nutrition|volume=38|issue=1_suppl|year=2014|pages=14S–22S|issn=0148-6071|doi=10.1177/0148607113520005}}</ref><ref name="EçaBarbosa2016">{{cite journal|last1=Eça|first1=Rosário|last2=Barbosa|first2=Elisabete|title=Short bowel syndrome: treatment options|journal=Journal of Coloproctology|volume=36|issue=4|year=2016|pages=262–272|issn=22379363|doi=10.1016/j.jcol.2016.07.002}}</ref><ref name="RodriguesSeetharam2011">{{cite journal|last1=Rodrigues|first1=Gabriel|last2=Seetharam|first2=Prasad|title=Short bowel syndrome: A review of management options|journal=Saudi Journal of Gastroenterology|volume=17|issue=4|year=2011|pages=229|issn=1319-3767|doi=10.4103/1319-3767.82573}}</ref>
**[[Complete blood count]] (CBC) may show:
*'''[[Complete blood count]] (CBC):'''
***[[anemia]] either [[Microcytic anemia|microcytic]] or [[Macrocytic anemia|macrocytic]]
**[[Anemia]] either [[Microcytic anemia|microcytic]] or [[Macrocytic anemia|macrocytic]]
**Low level of [[albumin]]
*'''Low levels of [[albumin]]'''
**High level of [[Acute phase protein|acute phase reactant]]  
*'''High levels of [[Acute phase protein|acute phase reactant]]'''
***High [[C-reactive protein]] ([[C-reactive protein|CRP]])
**High [[C-reactive protein]] ([[C-reactive protein|CRP]]) (normal- 0 to 10 mg/dl)
***High [[erythrocyte sedimentation rate]] ([[Erythrocyte sedimentation rate|ESR]])
**High [[erythrocyte sedimentation rate]] ([[Erythrocyte sedimentation rate|ESR]]) (normal for women is < 20 mm/hour and for men is <15 mm/hour)
**[[Liver function tests|Liver function test]]
*[[Liver function tests|'''Liver function test''']]
***High [[Aspartate transaminase|aspartate aminotransferase]] ([[Aspartate transaminase|AST]])
**High [[Aspartate transaminase|aspartate aminotransferase]] ([[Aspartate transaminase|AST]]) (normal-  8 to 48 U/L)
***High [[Alanine transaminase|alanine aminotransferase]] ([[Alanine transaminase|ALT]])  
**High [[Alanine transaminase|alanine aminotransferase]] ([[Alanine transaminase|ALT]]) (normal-  7 to 55 units per liter U/L)  
***High [[Bilirubin|serum bilirubin]]  
**High [[Bilirubin|serum bilirubin]] (normal - 0.1 to 1.2 mg/dl)
**Blood chemistry profile
*'''Blood chemistry profile'''
**[[Fecal fat]] test
**High [[blood urea nitrogen]] ([[Blood urea nitrogen|BUN]]) (normal- 7 to 20 mg/dl)
**[[Vitamin]] levels in the [[blood]]
**High serum [[creatinine]] (normal- 0.8 to 1.2 md/dl)
 
**[[Hyponatremia|Low sodium]] (normal- 135/145 mEq/L)
**[[Hypokalemia|Low potassium]] (normal- 3.5 to 5.5 mEq/L)
**Low [[chloride]] (normal- 97 to 107 mEq/L)
*'''[[Vitamin]] and [[mineral]] levels:'''
**Low levels of [[vitamin A]]
**Low levels of [[vitamin B12]]
**Low levels of [[vitamin C]]
**Low level of [[vitamin D]]
**Low level of [[Tocopherol|vitamin E]]
**Low level of [[vitamin K]]
**Low [[iron]]
**Low [[Folic Acid|folic acid]]
**[[Hypocalcemia|Low calcium]]
**[[Hypomagnesemia|Low magnesium]]
**Low [[phosphorus]]
**Low [[zinc]]
**Low [[chromium]]
**Low [[selenium]]
*'''High [[fecal fat]]'''
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


{{WH}}
[[Category:Medicine]]
{{WS}}
[[Category:Gastroenterology]]
[[Category:Surgery]]
[[Category:Up-To-Date]]

Latest revision as of 00:10, 30 July 2020

Short bowel syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Short bowel syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Short bowel syndrome laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Short bowel syndrome laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Short bowel syndrome laboratory findings

CDC on Short bowel syndrome laboratory findings

Short bowel syndrome laboratory findings in the news

Blogs on Short bowel syndrome laboratory findings

Directions to Hospitals Treating Short bowel syndrome

Risk calculators and risk factors for Short bowel syndrome laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

Laboratory findings consistent with the diagnosis of short bowel syndrome include anemia, hypoalbuminemia, low level of vitamins, minerals, and micronutrients. Level of acute phase reactants is high. Abnormal liver function tests including elevated liver enzymes and bilirubin might be seen. Fluid and electrolyte imbalance might be present. Fecal fat test is usually positive.

Laboratory Findings

Laboratory findings consistent with the diagnosis of short bowel syndrome include:[1][2][3][4][5][6][6][7][8][9][10]

References

  1. Wall, Elizabeth A. (2013). "An Overview of Short Bowel Syndrome Management: Adherence, Adaptation, and Practical Recommendations". Journal of the Academy of Nutrition and Dietetics. 113 (9): 1200–1208. doi:10.1016/j.jand.2013.05.001. ISSN 2212-2672.
  2. Botey, Mireia; Alastrué, Antonio; Haetta, Henrik; Fernández-Llamazares, Jaume; Clavell, Arantxa; Moreno, Pau (2017). "Long-Term Results of Serial Transverse Enteroplasty with Neovalve Creation for Extreme Short Bowel Syndrome: Report of Two Cases". Case Reports in Gastroenterology. 11 (1): 229–240. doi:10.1159/000452734. ISSN 1662-0631.
  3. Thompson, Jon S.; Weseman, Rebecca; Rochling, Fedja A.; Mercer, David F. (2011). "Current Management of the Short Bowel Syndrome". Surgical Clinics of North America. 91 (3): 493–510. doi:10.1016/j.suc.2011.02.006. ISSN 0039-6109.
  4. Sundaram A, Koutkia P, Apovian CM (2002). "Nutritional management of short bowel syndrome in adults". J. Clin. Gastroenterol. 34 (3): 207–20. PMID 11873098.
  5. Bechtold, Matthew L.; McClave, Stephen A.; Palmer, Lena B.; Nguyen, Douglas L.; Urben, Lindsay M.; Martindale, Robert G.; Hurt, Ryan T. (2014). "The Pharmacologic Treatment of Short Bowel Syndrome: New Tricks and Novel Agents". Current Gastroenterology Reports. 16 (7). doi:10.1007/s11894-014-0392-2. ISSN 1522-8037.
  6. 6.0 6.1 DiBaise, John K.; Young, Rosemary J.; Vanderhoof, Jon A. (2004). "Intestinal Rehabilitation and the Short Bowel Syndrome: Part 1". The American Journal of Gastroenterology. 99 (7): 1386–1395. doi:10.1111/j.1572-0241.2004.30345.x. ISSN 0002-9270.
  7. Keller, Jutta; Panter, Heidi; Layer, Peter (2004). "Management of the short bowel syndrome after extensive small bowel resection". Best Practice & Research Clinical Gastroenterology. 18 (5): 977–992. doi:10.1016/S1521-6918(04)00060-5. ISSN 1521-6918.
  8. Tappenden, Kelly A. (2014). "Pathophysiology of Short Bowel Syndrome". Journal of Parenteral and Enteral Nutrition. 38 (1_suppl): 14S–22S. doi:10.1177/0148607113520005. ISSN 0148-6071.
  9. Eça, Rosário; Barbosa, Elisabete (2016). "Short bowel syndrome: treatment options". Journal of Coloproctology. 36 (4): 262–272. doi:10.1016/j.jcol.2016.07.002. ISSN 2237-9363.
  10. Rodrigues, Gabriel; Seetharam, Prasad (2011). "Short bowel syndrome: A review of management options". Saudi Journal of Gastroenterology. 17 (4): 229. doi:10.4103/1319-3767.82573. ISSN 1319-3767.