Scleroderma overview: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
Common risk factors in the development of scleroderma include occupational and environmental exposure to certain [[chemicals]], certain [[genetic]] variations and [[infectious]] agents. Most commonly implicated occupational and environmental risk factors are exposure is to [[silica]], chlorinated and [[aromatic]] solvents as well as welding [[fumes]]. | |||
== Natural History, Complications and Prognosis== | == Natural History, Complications and Prognosis== | ||
Revision as of 17:19, 28 March 2018
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Scleroderma Microchapters |
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Treatment |
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Case Studies |
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Scleroderma overview On the Web |
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American Roentgen Ray Society Images of Scleroderma overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Scleroderma is a rare, chronic disease characterized by excessive deposits of collagen in the skin or other organs. The localized type of the disease, while disabling, tends not to be fatal. Diffuse scleroderma or systemic sclerosis, the generalized type of the disease, can be fatal as a result of heart, kidney, lung or intestinal damage.[1]
Historical Perspective
Classification
Pathophysiology
Causes
The cause of scleroderma has not been identified. There is a possibility of an underlying immunologic abnormality. To review risk factors for the development of scleroderma click here.
Differentiating Scleroderma from other Diseases
Epidemiology and Demographics
Risk Factors
Common risk factors in the development of scleroderma include occupational and environmental exposure to certain chemicals, certain genetic variations and infectious agents. Most commonly implicated occupational and environmental risk factors are exposure is to silica, chlorinated and aromatic solvents as well as welding fumes.
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Electrocardiogram
Chest X Ray
CT Scan
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
- ↑ Klippel J (ed). Systemic sclerosis and related syndromes. Primer on the rheumatic diseases, 11th edition. The Arthritis Society. 1997;269. ISBN 1-91242-316-2.