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{{familytree/start |summary=Abdominal mass causes}}
{{familytree | | | | | | | | A01 | | | A01='''Abdominal mass'''<ref name="urlACS/ASE Medical Student Core Curriculum">{{cite web |url=https://www.facs.org/education/program/core-curriculum#:~:text=The%20American%20College%20of%20Surgeons,school%20faculty%2C%20and%20clinical%20faculty. |title=ACS/ASE Medical Student Core Curriculum |format= |work= |accessdate=}}</ref>}}
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{{familytree | | | | | | C01 | | C02 | | | |C01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Abdominal wall mass'''<ref name="pmid24378391">{{cite journal |vauthors=Jo VY, Fletcher CD |title=WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition |journal=Pathology |volume=46 |issue=2 |pages=95–104 |date=February 2014 |pmid=24378391 |doi=10.1097/PAT.0000000000000050 |url=}}</ref><ref name="pmid31867236">{{cite journal |vauthors=Li M, Zhang L, Xu XJ, Shi Z, Zhao XM |title=CT and MRI features of tumors and tumor-like lesions in the abdominal wall |journal=Quant Imaging Med Surg |volume=9 |issue=11 |pages=1820–1839 |date=November 2019 |pmid=31867236 |pmc=6902146 |doi=10.21037/qims.2019.09.03 |url=}}</ref><br>
❑Primary tumors ([[WHO]] classification)<br>
:❑[[Adipocyte|Adipocytic]] tumors ([[lipoma]], [[liposarcoma]]) <br>
:❑Fibroblastic/myofibroblastic tumors ([[Desmoid tumor differential diagnosis|desmoid tumor]])<br>
:❑Nerve sheath tumors ([[schwannoma]], [[neurofibroma]])<br>
:❑[[Hemangioma]]s <br>
:❑Undifferentiated pleomorphic [[sarcoma]]s <br>
:❑Smooth muscle tumor ([[leiomyoma]] (not included in WHO classification)<br>
❑[[Metastasis]]<br>
❑Tumor-like mass<br>
:❑[[Endometriosis]], [[abscess]], [[hematoma]]<br>
:❑[[Hernia]]s ([[epigastric hernia|epigastric]], [[umbilical hernia|umbilical]], [[incisional hernia|incisional]], and [[spigelian hernia|spigelian]])| C02='''Intra-abdominal/<br> [[retroperitoneal]] mass''' }}
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{{familytree | | D01 | | D02| | D03 | | D04 | | D05 |D01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Hepatic mass'''<ref name="pmid20955964">{{cite journal |vauthors=vom Dahl S, Mengel E |title=Lysosomal storage diseases as differential diagnosis of hepatosplenomegaly |journal=Best Pract Res Clin Gastroenterol |volume=24 |issue=5 |pages=619–28 |date=October 2010 |pmid=20955964 |doi=10.1016/j.bpg.2010.09.001 |url=}}</ref><ref name="pmid3003936">{{cite journal |vauthors=Maharaj B, Cooppan RM, Maharaj RJ, Desai DK, Ranchod HA, Siddie-Ganie FM, Goqwana MB, Ganie AS, Gaffar MS, Leary WP |title=Causes of hepatomegaly at King Edward VIII Hospital, Durban. A prospective study of 240 black patients |journal=S. Afr. Med. J. |volume=69 |issue=3 |pages=183–4 |date=February 1986 |pmid=3003936 |doi= |url=}}</ref><br>
❑[[Hepatitis]] (infectious, [[DILI]], [[Alcoholic liver disease|alcoholic]],<br> [[NASH]], [[autoimmune hepatitis|autoimmune]], [[Wilson's disease]]<br>
❑Storage diseases ([[glycogen storage disease]], [[lysosomal storage disease]], [[lipid storage disease]], [[hemochromatosis]])<br>
❑[[Tumors]]<br>
:❑Primary Benign:[[Hepatic adenoma|adenoma]], [[Focal nodular hyperplasia|FNH]]<br>
:❑Primary malignant:[[Hepatocellular carcinoma|HCC]], [[cholangiocarcinoma]]<br>
:❑Metastatic: [[Hemangioma]], [[lymphoma]],<br> [[myeloma]] and solid tumors.<br>
❑[[Cholestasis]] ([[Primary biliary cirrhosis|PBC]], [[Primary sclerosing cholangitis|PSC]]) | D02=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Splenic mass'''<ref name="pmid29135986">{{cite journal |vauthors=Curovic Rotbain E, Lund Hansen D, Schaffalitzky de Muckadell O, Wibrand F, Meldgaard Lund A, Frederiksen H |title=Splenomegaly - Diagnostic validity, work-up, and underlying causes |journal=PLoS ONE |volume=12 |issue=11 |pages=e0186674 |date=2017 |pmid=29135986 |pmc=5685614 |doi=10.1371/journal.pone.0186674 |url=}}</ref><br>❑[[Infections|Infectious]]:[[Infectious Mononucleosis|IM]], [[liver abscess]],<br>[[echinococcosis]]<br>❑[[Myeloproliferative disorders|Myeloproliferative]] ([[lymphoma]]s<br> and [[leukemia]]s)<br>
❑Storage ([[Gaucher’s disease|Gaucher's]],  [[Niemann-Pick disease]])<br>❑Infiltrative:[[amyloidosis]], [[sarcoidosis]]<br>
❑Miscellineous ([[Portal hypertension|PH]], [[metastases]] ([[lung cancer]] or [[breast cancer]], [[Felty's syndrome]])| D03=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Pancreatic mass'''<ref name="pmid27065727">{{cite journal |vauthors=Karoumpalis I, Christodoulou DK |title=Cystic lesions of the pancreas |journal=Ann Gastroenterol |volume=29 |issue=2 |pages=155–61 |date=2016 |pmid=27065727 |pmc=4805734 |doi=10.20524/aog.2016.0007 |url=}}</ref><ref name="pmid21620466">{{cite journal |vauthors=Vincent A, Herman J, Schulick R, Hruban RH, Goggins M |title=Pancreatic cancer |journal=Lancet |volume=378 |issue=9791 |pages=607–20 |date=August 2011 |pmid=21620466 |pmc=3062508 |doi=10.1016/S0140-6736(10)62307-0 |url=}}</ref><br>❑[[Pancreatic cyst]]<br>
:❑[[Pancreatic cancer differential diagnosis|Neoplastic]] ([[Mucinous cystadenocarcinoma differential diagnosis|mucinous]], [[serous]], [[Intraductal papillary mucinous neoplasm|intraductal papillary]], and solid pseudopapillary)<br>
:❑Non-neoplastic (true, [[mucinous]])<br>
:❑[[inflammation|Inflammatory]] ([[Pancreatic pseudocyst|pseudocyst]], [[acute]] fluid collection)<br>
❑Solid:<br>
:❑[[Adenocarcinoma]]s ([[Pancreatic cancer classification|ductal]], [[bile duct]], [[Pancreatic cancer classification|ampullar]] and [[Small intestine cancer classification|duodenal]])
:❑[[Pancreatic neuroendocrine tumor]]s<br>
:❑Others ([[lymphoma]] and [[metastasis]])| D04=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''[[Retroperitoneal]] mass'''<ref name="pmid30559557">{{cite journal |vauthors=Mota MMDS, Bezerra ROF, Garcia MRT |title=Practical approach to primary retroperitoneal masses in adults |journal=Radiol Bras |volume=51 |issue=6 |pages=391–400 |date=2018 |pmid=30559557 |pmc=6290739 |doi=10.1590/0100-3984.2017.0179 |url=}}</ref><br>(majority tumors are [[malignant]])<br>
❑[[Liposarcoma]]<br>
❑[[Incidentaloma]]<br>
❑[[Lymphoma]]|D05=[[Abdominal Aortic Aneurysm]](AAA)|}}
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<span style="font-size:85%"> '''Abbreviations:''' '''ACS:''' Acute coronary syndrome; '''AAA:''' Abdominal aortic aneurysm; '''RUQ:''' Right upper quadrant; '''RLQ:''' Right lower quadrant; '''LUQ:''' Left upper quadrant; '''LLQ:''' Left lower quadrant</span>
<span style="font-size:85%"> '''Abbreviations:''' '''ACS:''' Acute coronary syndrome; '''AAA:''' Abdominal aortic aneurysm; '''RUQ:''' Right upper quadrant; '''RLQ:''' Right lower quadrant; '''LUQ:''' Left upper quadrant; '''LLQ:''' Left lower quadrant</span>

Revision as of 08:33, 14 August 2020

Shown below is an algorithm summarizing the diagnosis of abdominal mass according the the [...] guidelines.


Abbreviations: ACS: Acute coronary syndrome; AAA: Abdominal aortic aneurysm; RUQ: Right upper quadrant; RLQ: Right lower quadrant; LUQ: Left upper quadrant; LLQ: Left lower quadrant

 
 
 
Abdominal mass
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
History and brief physical exam
Past medical history
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hemodynamic instability
 
Stable
 
{{{ ! }}}
 
 
{{{ ! }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Characterize the mass:
❑Pulsatile mass
❑Constant mass


Associated pain:

❑ Site (eg, a particular quadrant or diffuse, a change in location may reflect progression of the disease
❑ Onset (eg, sudden, gradual)
❑ Quality (eg, dull, sharp, colicky, waxing and waning)
❑ Aggravating and relieving factors (e.g, Is the pain related to your meals?)
❑ Intensity (scale of 0-10/ 0-5 with the maximum number; 10/5 being the worst pain of life)
❑ Time course (eg, hours versus weeks, constant or intermittent)
❑ Radiation (eg, to the shoulder, back, flank, groin, or chest)

Associated symptoms

Shortness of breath
Altered mental status
Nausea & vomiting
Diaphoresis
Fever
Hematuria
Anorexia
Bloody stool
Weight loss
Vaginal discharge
Penile discharge
Jaundice
Mal-digestion
Flatulence
Fatigue
Scrotal pain/swelling
❑ Recent trauma
❑ Symptoms suggestive of sepsis

Detailed history:

❑ Age (Patients above 50 years old are more likely to have severe diseases or cancers, such as ruptured abdominal aortic aneurysm or colon cancer)
❑ Past medical history (to exclude risk factors for cardiovascular diseases or peripheral vascular disease)
❑ Past surgical history (for previous abdominal surgeries)
❑ Menstrual and contraceptive history (pregnancy should be excluded in all women of childbearing age with abdominal mass)
❑ Social history (alcohol abuse predispose to pancreatitis and hepatitis, smoking also predisposes to different types of cancers, eg. cancer bladder, which may cause abdominal pain)
❑ Occupational history (exposure to chemicals or toxins)
❑ Travel history
❑ Medications (for over the counter drugs as
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:

❑ Vital signs

Temperature
Heart rate (tachycardia)
Blood pressure (hypotension)
Respiratory rate (tachypnea)

❑ Skin

Diaphoresis
Pallor
Jaundice
Dehydration

❑ Inspection

❑ If the patient is lying still in bed with knees bent, this is suggestive of organ rupture and resulting peritonitis
❑ Signs of previous surgery
❑ Abdominal pulsations
❑ Signs of systemic disease eg,
Pallor, suggestive of bleeding
Spider angiomata, suggestive of cirrhosis

❑ Auscultation

❑ Abdominal crepitations
❑ Reduced bowel sounds
❑ Increased bowel sounds
❑ Bruit, suggestive of abdominal aortic aneurysm

❑ Palpation

❑ Rigidity
Guarding
❑ Abdominal tenderness
Distension
❑ Detection of masses on palpating the abdomen
Carnett's sign

Psoas sign (suggestive of retrocecal appendix)
Cullen's sign
Grey-Turner's sign
Digital rectal exam (tenderness may be present in retrocecal appendicitis)
Pelvic exam in females
Testicular examination in males
❑ Cardiovascular system
❑ Respiratory system
❑ Anorectal (bleeding)
Signs of sepsis: tachycardia, decreased urination, and hyperglycemia, confusion, metabolic acidosis with compensatory respiratory alkalosis, low blood pressure, decreased systemic vascular resistance, higher cardiac output, and coagulation dysfunctions

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Consider extraabdominal differential diagnosis:
❑ aaaa
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Assess hemodynamic stability
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If the patient is unstable,
Stabilize the patient:
❑ Establish two large-bore intravenous peripheral lines
NPO until the patient is stable
❑ Supportive care (fluids and electrolyes as required)
❑ Place nasogastric tube if there is bleeding, obstruction, significant nausea or vomiting
❑ Place foley catheter to monitor volume status
❑ Cardiac monitoring
❑ Supplemental oxygen as needed
❑ Administer early antibiotics if indicated
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If the patient is stable,
Order laboratory tests:
Pregnancy test (required in women of child-bearing age)
CBC
Hematocrit
Urinalysis
Serum electrolytes
ESR
ABG
D dimer
Serum lactate
BUN
Creatinine
Amylase
Lipase
Triglyceride
❑ Total bilirubin
❑ Direct bilirubin
Albumin
AST
ALT
Alkaline phosphatase
GGT
❑ Stool for ova and parasites
❑ C. difficile culture and toxin assay

Order imaging studies:
❑ Order urgent trans abdominal ultrasound (TAUSG)
Abdominal CT
ECG
MRCP
Abdominal x-ray
Angiography
❑ Diagnostic paracentesis


*Order the tests to rule in a suspected diagnosis
or to assess a case of unclear etiology

*In case of elderly patients, immunocompromised
or those unable to provide a comprehensive
history, order broader range of tests
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Signs of peritonitis or shock
Fever
❑ Abdominal tenderness
❑ Abdominal gaurding
❑ Rebound tenderness (blumberg sign)
❑ Diffuse abdominal rigidity
Confusion
❑ Weakness
❑ Low blood pressure
❑ Decreased urine output
❑ Tachycardia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
Yes