Retinitis pathophysiology

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Overview

Pathophysiology

=Cytomegalovirus

  • Retinitis, caused by cytomegalovirus (CMV), involves the infection of all layers of the retinal tissue.
  • Spread of the the infection will occur at approximately 24 nanometers per day.
  • Primarily infected areas include the RPE and the subjacent choroid.
  • Infection will consist of a vast amount of cellular necrosis across the retina; with the enlargement of infected cells, evidently hosting viral inclusions.
  • CMV retinitis, post-treatment, will commonly persist on the previously scarred, retinal tissue. [1]

References

  1. American Academy of Ophthalmology. Pathophysiology of CMV Retinitis. http://www.aao.org/focalpointssnippetdetail.aspx?id=bc891841-b847-4210-a66b-2bb28d1ef1bf. Accessed April 12, 2016.

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