RNF14: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Latest revision as of 02:31, 27 October 2017

E3 ubiquitin-protein ligase RNF14 is an enzyme that in humans is encoded by the RNF14 gene.^[1]^[2]^[3]

Function

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.^[3]

Interactions

RNF14 has been shown to interact with the Androgen receptor.^[1]^[4]^[5]^[6]

References

↑ ^1.0 ^1.1 Kang HY, Yeh S, Fujimoto N, Chang C (Apr 1999). "Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor". J Biol Chem. 274 (13): 8570–6. doi:10.1074/jbc.274.13.8570. PMID 10085091.
↑ Ueki N, Seki N, Yano K, Masuho Y, Saito T, Muramatsu M (Jun 1999). "Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif". Biochim Biophys Acta. 1445 (2): 232–6. doi:10.1016/s0167-4781(99)00045-7. PMID 10320776.
↑ ^3.0 ^3.1 "Entrez Gene: RNF14 ring finger protein 14".
↑ Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C (Feb 2002). "A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth". J. Biol. Chem. 277 (7): 4609–17. doi:10.1074/jbc.M108312200. PMID 11673464.
↑ He B, Minges JT, Lee LW, Wilson EM (Mar 2002). "The FXXLF motif mediates androgen receptor-specific interactions with coregulators". J. Biol. Chem. 277 (12): 10226–35. doi:10.1074/jbc.M111975200. PMID 11779876.
↑ He B, Wilson EM (Mar 2003). "Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs". Mol. Cell. Biol. 23 (6): 2135–50. doi:10.1128/mcb.23.6.2135-2150.2003. PMC 149467. PMID 12612084.

Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (1999). "Selection system for genes encoding nuclear-targeted proteins". Nat. Biotechnol. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615.
Ito K, Adachi S, Iwakami R, Yasuda H, Muto Y, Seki N, Okano Y (2001). "N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x. PMID 11322894.
Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C (2002). "A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth". J. Biol. Chem. 277 (7): 4609–17. doi:10.1074/jbc.M108312200. PMID 11673464.
Ueda T, Mawji NR, Bruchovsky N, Sadar MD (2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells". J. Biol. Chem. 277 (41): 38087–94. doi:10.1074/jbc.M203313200. PMID 12163482.
He B, Wilson EM (2003). "Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs". Mol. Cell. Biol. 23 (6): 2135–50. doi:10.1128/MCB.23.6.2135-2150.2003. PMC 149467. PMID 12612084.
Mestayer C, Blanchère M, Jaubert F, Dufour B, Mowszowicz I (2003). "Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines". Prostate. 56 (3): 192–200. doi:10.1002/pros.10229. PMID 12772188.
Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, Chang C (2004). "Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells". Mol. Cell. Biol. 24 (5): 2202–13. doi:10.1128/MCB.24.5.2202-2213.2004. PMC 350564. PMID 14966297.
Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, Kung HJ, Shih HM (2004). "Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx". Mol. Cell. Biol. 24 (24): 10529–41. doi:10.1128/MCB.24.24.10529-10541.2004. PMC 533990. PMID 15572661.
Yang Z, Chang YJ, Miyamoto H, Ni J, Niu Y, Chen Z, Chen YL, Yao JL, di Sant'Agnese PA, Chang C (2007). "Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth". Mol. Endocrinol. 21 (2): 343–58. doi:10.1210/me.2006-0104. PMID 17082327.
Yang Z, Chang YJ, Miyamoto H, Yeh S, Yao JL, di Sant'Agnese PA, Tsai MY, Chang C (2007). "Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54". Endocrinology. 148 (3): 1340–9. doi:10.1210/en.2006-0716. PMID 17110431.
Kikuchi H, Uchida C, Hattori T, Isobe T, Hiramatsu Y, Kitagawa K, Oda T, Konno H, Kitagawa M (2007). "ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells". Carcinogenesis. 28 (8): 1752–8. doi:10.1093/carcin/bgm120. PMID 17510080.

External links

RNF14 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
NURSA C127

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[pmid10085091-1] 1.0 ^1.1 Kang HY, Yeh S, Fujimoto N, Chang C (Apr 1999). "Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor". J Biol Chem. 274 (13): 8570–6. doi:10.1074/jbc.274.13.8570. PMID 10085091.

[pmid10320776-2] Ueki N, Seki N, Yano K, Masuho Y, Saito T, Muramatsu M (Jun 1999). "Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif". Biochim Biophys Acta. 1445 (2): 232–6. doi:10.1016/s0167-4781(99)00045-7. PMID 10320776.

[entrez-3] 3.0 ^3.1 "Entrez Gene: RNF14 ring finger protein 14".

[pmid11673464-4] Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C (Feb 2002). "A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth". J. Biol. Chem. 277 (7): 4609–17. doi:10.1074/jbc.M108312200. PMID 11673464.

[pmid11779876-5] He B, Minges JT, Lee LW, Wilson EM (Mar 2002). "The FXXLF motif mediates androgen receptor-specific interactions with coregulators". J. Biol. Chem. 277 (12): 10226–35. doi:10.1074/jbc.M111975200. PMID 11779876.

[pmid12612084-6] He B, Wilson EM (Mar 2003). "Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs". Mol. Cell. Biol. 23 (6): 2135–50. doi:10.1128/mcb.23.6.2135-2150.2003. PMC 149467. PMID 12612084.

[1]

[2]

[3]

[4]

[5]

[6]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''E3 ubiquitin-protein ligase RNF14''' is an [[enzyme]] that in humans is encoded by the ''RNF14'' [[gene]].<ref name="pmid10085091">{{cite journal | vauthors = Kang HY, Yeh S, Fujimoto N, Chang C | title = Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor | journal = J Biol Chem | volume = 274 | issue = 13 | pages = 8570–6 | date = Apr 1999 | pmid = 10085091 | pmc =  | doi = 10.1074/jbc.274.13.8570 }}</ref><ref name="pmid10320776">{{cite journal | vauthors = Ueki N, Seki N, Yano K, Masuho Y, Saito T, Muramatsu M | title = Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif | journal = Biochim Biophys Acta | volume = 1445 | issue = 2 | pages = 232–6 | date = Jun 1999 | pmid = 10320776 | pmc =  | doi = 10.1016/s0167-4781(99)00045-7 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RNF14 ring finger protein 14| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9604| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Ring finger protein 14
- | HGNCid = 10058
- | Symbol = RNF14
- | AltSymbols =; ARA54; FLJ26004; HFB30; HRIHFB2038
- | OMIM = 605675
- | ECnumber =
- | Homologene = 6573
- | MGIid = 1929668
- | GeneAtlas_image1 = PBB_GE_RNF14_201823_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_RNF14_201824_at_tn.png
- | Function = {{GNF_GO|id=GO:0003713 |text = transcription coactivator activity}} {{GNF_GO|id=GO:0004842 |text = ubiquitin-protein ligase activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0016874 |text = ligase activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}} {{GNF_GO|id=GO:0050681 |text = androgen receptor binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
- | Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006512 |text = ubiquitin cycle}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0030521 |text = androgen receptor signaling pathway}} {{GNF_GO|id=GO:0045893 |text = positive regulation of transcription, DNA-dependent}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 9604
-    | Hs_Ensembl = ENSG00000013561
-    | Hs_RefseqProtein = NP_004281
-    | Hs_RefseqmRNA = NM_004290
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 5
-    | Hs_GenLoc_start = 141326621
-    | Hs_GenLoc_end = 141348934
-    | Hs_Uniprot = Q9UBS8
-    | Mm_EntrezGene = 56736
-    | Mm_Ensembl = ENSMUSG00000060450
-    | Mm_RefseqmRNA = NM_020012
-    | Mm_RefseqProtein = NP_064396
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 18
-    | Mm_GenLoc_start = 38422658
-    | Mm_GenLoc_end = 38443821
-    | Mm_Uniprot = Q7TPR0
-  }}
-}}
-'''Ring finger protein 14''', also known as '''RNF14''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RNF14 ring finger protein 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9604| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.<ref name="entrez">{{cite web | title = Entrez Gene: RNF14 ring finger protein 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9604| accessdate = }}</ref>
-}}
-==See also==
+== Interactions ==
+RNF14 has been shown to [[Protein-protein interaction|interact]] with the [[Androgen receptor]].<ref name = pmid10085091 /><ref name = pmid11673464>{{cite journal | vauthors = Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C | title = A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth | journal = J. Biol. Chem. | volume = 277 | issue = 7 | pages = 4609–17 | date = Feb 2002 | pmid = 11673464 | doi = 10.1074/jbc.M108312200 }}</ref><ref name = pmid11779876>{{cite journal | vauthors = He B, Minges JT, Lee LW, Wilson EM | title = The FXXLF motif mediates androgen receptor-specific interactions with coregulators | journal = J. Biol. Chem. | volume = 277 | issue = 12 | pages = 10226–35 | date = Mar 2002 | pmid = 11779876 | doi = 10.1074/jbc.M111975200 }}</ref><ref name = pmid12612084>{{cite journal | vauthors = He B, Wilson EM | title = Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs | journal = Mol. Cell. Biol. | volume = 23 | issue = 6 | pages = 2135–50 | date = Mar 2003 | pmid = 12612084 | pmc = 149467 | doi =  10.1128/mcb.23.6.2135-2150.2003}}</ref>
+== See also ==
 * [[RING finger domain]]
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
+{{Clear}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M | title = Selection system for genes encoding nuclear-targeted proteins | journal = Nat. Biotechnol. | volume = 16 | issue = 13 | pages = 1338–42 | year = 1999 | pmid = 9853615 | doi = 10.1038/4315 }}
-| citations =
+* {{cite journal | vauthors = Ito K, Adachi S, Iwakami R, Yasuda H, Muto Y, Seki N, Okano Y | title = N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8 | journal = Eur. J. Biochem. | volume = 268 | issue = 9 | pages = 2725–32 | year = 2001 | pmid = 11322894 | doi = 10.1046/j.1432-1327.2001.02169.x }}
-*{{cite journal  | author=Ueki N, Oda T, Kondo M, ''et al.'' |title=Selection system for genes encoding nuclear-targeted proteins. |journal=Nat. Biotechnol. |volume=16 |issue= 13 |pages= 1338-42 |year= 1999 |pmid= 9853615 |doi= 10.1038/4315 }}
+* {{cite journal | vauthors = Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C | title = A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth | journal = J. Biol. Chem. | volume = 277 | issue = 7 | pages = 4609–17 | year = 2002 | pmid = 11673464 | doi = 10.1074/jbc.M108312200 }}
-*{{cite journal  | author=Kang HY, Yeh S, Fujimoto N, Chang C |title=Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. |journal=J. Biol. Chem. |volume=274 |issue= 13 |pages= 8570-6 |year= 1999 |pmid= 10085091 |doi=  }}
+* {{cite journal | vauthors = Ueda T, Mawji NR, Bruchovsky N, Sadar MD | title = Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells | journal = J. Biol. Chem. | volume = 277 | issue = 41 | pages = 38087–94 | year = 2002 | pmid = 12163482 | doi = 10.1074/jbc.M203313200 }}
-*{{cite journal  | author=Ueki N, Seki N, Yano K, ''et al.'' |title=Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif. |journal=Biochim. Biophys. Acta |volume=1445 |issue= 2 |pages= 232-6 |year= 1999 |pmid= 10320776 |doi=  }}
+* {{cite journal | vauthors = He B, Wilson EM | title = Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs | journal = Mol. Cell. Biol. | volume = 23 | issue = 6 | pages = 2135–50 | year = 2003 | pmid = 12612084 | pmc = 149467 | doi = 10.1128/MCB.23.6.2135-2150.2003 }}
-*{{cite journal  | author=Ito K, Adachi S, Iwakami R, ''et al.'' |title=N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. |journal=Eur. J. Biochem. |volume=268 |issue= 9 |pages= 2725-32 |year= 2001 |pmid= 11322894 |doi=  }}
+* {{cite journal | vauthors = Mestayer C, Blanchère M, Jaubert F, Dufour B, Mowszowicz I | title = Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines | journal = Prostate | volume = 56 | issue = 3 | pages = 192–200 | year = 2003 | pmid = 12772188 | doi = 10.1002/pros.10229 }}
-*{{cite journal  | author=Miyamoto H, Rahman M, Takatera H, ''et al.'' |title=A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 4609-17 |year= 2002 |pmid= 11673464 |doi= 10.1074/jbc.M108312200 }}
+* {{cite journal | vauthors = Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, Chang C | title = Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells | journal = Mol. Cell. Biol. | volume = 24 | issue = 5 | pages = 2202–13 | year = 2004 | pmid = 14966297 | pmc = 350564 | doi = 10.1128/MCB.24.5.2202-2213.2004 }}
-*{{cite journal  | author=Ueda T, Mawji NR, Bruchovsky N, Sadar MD |title=Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. |journal=J. Biol. Chem. |volume=277 |issue= 41 |pages= 38087-94 |year= 2002 |pmid= 12163482 |doi= 10.1074/jbc.M203313200 }}
+* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional Proteomics Mapping of a Human Signaling Pathway | journal = Genome Res. | volume = 14 | issue = 7 | pages = 1324–32 | year = 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, Kung HJ, Shih HM | title = Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx | journal = Mol. Cell. Biol. | volume = 24 | issue = 24 | pages = 10529–41 | year = 2004 | pmid = 15572661 | pmc = 533990 | doi = 10.1128/MCB.24.24.10529-10541.2004 }}
-*{{cite journal  | author=He B, Wilson EM |title=Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs. |journal=Mol. Cell. Biol. |volume=23 |issue= 6 |pages= 2135-50 |year= 2003 |pmid= 12612084 |doi=  }}
+* {{cite journal | vauthors = Yang Z, Chang YJ, Miyamoto H, Ni J, Niu Y, Chen Z, Chen YL, Yao JL, di Sant'Agnese PA, Chang C | title = Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth | journal = Mol. Endocrinol. | volume = 21 | issue = 2 | pages = 343–58 | year = 2007 | pmid = 17082327 | doi = 10.1210/me.2006-0104 }}
-*{{cite journal  | author=Mestayer C, Blanchère M, Jaubert F, ''et al.'' |title=Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines. |journal=Prostate |volume=56 |issue= 3 |pages= 192-200 |year= 2003 |pmid= 12772188 |doi= 10.1002/pros.10229 }}
+* {{cite journal | vauthors = Yang Z, Chang YJ, Miyamoto H, Yeh S, Yao JL, di Sant'Agnese PA, Tsai MY, Chang C | title = Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54 | journal = Endocrinology | volume = 148 | issue = 3 | pages = 1340–9 | year = 2007 | pmid = 17110431 | doi = 10.1210/en.2006-0716 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+* {{cite journal | vauthors = Kikuchi H, Uchida C, Hattori T, Isobe T, Hiramatsu Y, Kitagawa K, Oda T, Konno H, Kitagawa M | title = ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells | journal = Carcinogenesis | volume = 28 | issue = 8 | pages = 1752–8 | year = 2007 | pmid = 17510080 | doi = 10.1093/carcin/bgm120 }}
-*{{cite journal  | author=Wang L, Hsu CL, Ni J, ''et al.'' |title=Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 2202-13 |year= 2004 |pmid= 14966297 |doi=  }}
-*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Lin DY, Fang HI, Ma AH, ''et al.'' |title=Negative modulation of androgen receptor transcriptional activity by Daxx. |journal=Mol. Cell. Biol. |volume=24 |issue= 24 |pages= 10529-41 |year= 2004 |pmid= 15572661 |doi= 10.1128/MCB.24.24.10529-10541.2004 }}
-*{{cite journal  | author=Yang Z, Chang YJ, Miyamoto H, ''et al.'' |title=Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth. |journal=Mol. Endocrinol. |volume=21 |issue= 2 |pages= 343-58 |year= 2007 |pmid= 17082327 |doi= 10.1210/me.2006-0104 }}
-*{{cite journal  | author=Yang Z, Chang YJ, Miyamoto H, ''et al.'' |title=Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54. |journal=Endocrinology |volume=148 |issue= 3 |pages= 1340-9 |year= 2007 |pmid= 17110431 |doi= 10.1210/en.2006-0716 }}
-*{{cite journal  | author=Kikuchi H, Uchida C, Hattori T, ''et al.'' |title=ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells. |journal=Carcinogenesis |volume=28 |issue= 8 |pages= 1752-8 |year= 2007 |pmid= 17510080 |doi= 10.1093/carcin/bgm120 }}
-}}
 {{refend}}
 == External links ==
-* {{MeshName|RNF14+protein,+human}}
+* {{MeshName|RNF14+protein,+human|3=RNF14 protein, human}}
+*{{NURSA|C127}}
+{{NLM content}}
+{{Transcription coregulators}}
+[[Category:Gene expression]]
+[[Category:Transcription coregulators]]
+[[Category:RING finger proteins]]
-{{protein-stub}}
+{{gene-5-stub}}
-{{WikiDoc Sources}}

v t e Transcription coregulators
Coactivators	ARA (54, 55, 70) BCAS3 CARM1 p300-CBP (EP300, CREBBP) CRTC (1, 2, 3) DRIP/TRAP (MED1 Drip205/Trap220) MN1 PCAF PNRC (1, 2) PPARGC (1A, 1B) TGFB1I1 NCOA1 (SRC-1) NCOA2 (GRIP1/SRC-2/TIF2) NCOA3 (AIB/SRC-3/TRAM-1) NCOA4 (ARA70) NCOA5 (CIA) NCOA6 (RAP250) NCOA7 (ERAP140)
Corepressors	CTBP (1, 2) Hairless homolog LCOR NRIP1 (RIP140) PELP-1 RCOR1 Rb SIN3A SIN3B Tripartite motif family TRIM (24, 28, 33) NCOR1 NCOR2 (SMRT)
ATP-dependent remodeling factors	Chromatin Structure Remodeling (RSC) Complex SWI/SNF

RNF14: Difference between revisions

Latest revision as of 02:31, 27 October 2017

Contents

Function

Interactions

See also

References

Further reading

External links

Navigation menu