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{{Pulmonary hypertension}}
{{Pulmonary hypertension}}
{{CMG}}: {{AE}} {{AG}}
{{CMG}}: {{AE}} {{Jose}}
==Overview==
==Overview==
[[Pulmonary hypertension]] was first described by [[Ernst von Romberg]], a German physician, in 1891.
[[Pulmonary hypertension]] was first described by [[Ernst von Romberg]], a German physician, in 1891.
==Historical Perspective==
==Historical Perspective==
*[[Pulmonary hypertension]] was first described by [[Ernst von Romberg]], a German physician, in 1891.
*[[Pulmonary hypertension]] was first described by [[Ernst von Romberg]], a German physician, in 1891.
*[[Dresdale]] investigated the effects of [[tolzoline]] in a woman with [[pulmonary arterial hypertension]] causing a sudden reduction in pulmonary vascular resistance;
* In 1929, Werner Forssman demonstrated that it was possible to perform [[Right heart catheterization|right-sided catheterization]] in humans by performing [[catheterization]] on himself.
*In the late 1960s there was an epidemic of [[pulmonary arterial hypertension]] induced by aminorex which sparked interest on the disease;
* In 1951, Dresdale coined the term primary pulmonary hypertension after describing series of cases of this new pathology. He also investigated the effects of [[tolzoline]] in a woman with [[pulmonary arterial hypertension]] causing a sudden reduction in pulmonary vascular resistance.
*[[Pulmonary hypertension]] was first classified into primary and secondary in 1973 during the World Health Organization (WHO) meeting on PH in Geneva, Switzerland;
*In the late 1960s, there was an epidemic of [[pulmonary arterial hypertension]] induced by aminorex, which sparked interest in the disease.
*[[Pulmonary hypertension]] was first classified into primary and secondary in 1973 during the World Health Organization (WHO) meeting on PH in Geneva, Switzerland.
*[[Bosentan]] was approved to treat [[pulmonary hypertension]] in 2001, and [[sildenafil]] was approved in 2005.<ref name="pmid19561874">{{cite journal| author=Barst RJ| title=Pulmonary hypertension: past, present and future. | journal=Ann Thorac Med | year= 2008 | volume= 3 | issue= 1 | pages= 1-4 | pmid=19561874 | doi=10.4103/1817-1737.37832 | pmc=2700428 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19561874  }} </ref>
*[[Bosentan]] was approved to treat [[pulmonary hypertension]] in 2001, and [[sildenafil]] was approved in 2005.<ref name="pmid19561874">{{cite journal| author=Barst RJ| title=Pulmonary hypertension: past, present and future. | journal=Ann Thorac Med | year= 2008 | volume= 3 | issue= 1 | pages= 1-4 | pmid=19561874 | doi=10.4103/1817-1737.37832 | pmc=2700428 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19561874  }} </ref>


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Up-To-Date]]

Latest revision as of 14:01, 9 June 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]

Overview

Pulmonary hypertension was first described by Ernst von Romberg, a German physician, in 1891.

Historical Perspective

References

  1. Barst RJ (2008). "Pulmonary hypertension: past, present and future". Ann Thorac Med. 3 (1): 1–4. doi:10.4103/1817-1737.37832. PMC 2700428. PMID 19561874.