Primary biliary cirrhosis risk factors: Difference between revisions
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{{Primary biliary cirrhosis}} | {{Primary biliary cirrhosis}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{AA}} | ||
==Overview== | ==Overview== | ||
Common risk factors in the development of primary biliary cirrhosis may be occupational, environmental, genetic, and microbial. | |||
==Risk Factors== | ==Risk Factors== | ||
*The most potent risk factor in the development of primary biliary cirrhosis is positive family history. Other risk factors include age (30-60 years), female sex, infections and environmental toxins. | |||
*The most potent risk factor in the development of | |||
===Common Risk Factors=== | ===Common Risk Factors=== | ||
*Common risk factors in the development of | *Common risk factors in the development of Primary biliary cirrhosis may be occupational, environmental, genetic, and microbial. | ||
*Common risk factors in the development of | *Common risk factors in the development of primary biliary cirrhosis include: | ||
** | **Age: 30-60 years of age at highest risk | ||
** | **Sex: Female sex is at higher risk | ||
** | **Geographic distribution: Increased risk in North America and northern Europe. | ||
**Genetic predisposition: HLA-DRB1*0801 haplotype | |||
===Less Common Risk Factors=== | ===Less Common Risk Factors=== | ||
*Less common risk factors in the development of | *Less common risk factors in the development of primary biliary cirrhosis include: | ||
** | **Infections | ||
** | **Cigarette smoking | ||
** | **Environmental toxins | ||
==References== | ==References== |
Revision as of 04:44, 21 October 2017
Primary Biliary Cirrhosis Microchapters |
Differentiating Primary Biliary Cirrhosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
Common risk factors in the development of primary biliary cirrhosis may be occupational, environmental, genetic, and microbial.
Risk Factors
- The most potent risk factor in the development of primary biliary cirrhosis is positive family history. Other risk factors include age (30-60 years), female sex, infections and environmental toxins.
Common Risk Factors
- Common risk factors in the development of Primary biliary cirrhosis may be occupational, environmental, genetic, and microbial.
- Common risk factors in the development of primary biliary cirrhosis include:
- Age: 30-60 years of age at highest risk
- Sex: Female sex is at higher risk
- Geographic distribution: Increased risk in North America and northern Europe.
- Genetic predisposition: HLA-DRB1*0801 haplotype
Less Common Risk Factors
- Less common risk factors in the development of primary biliary cirrhosis include:
- Infections
- Cigarette smoking
- Environmental toxins