Pleomorphic adenoma diagnostic study of choice: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
(Created page with "__NOTOC__ {{Pleomorphic adenoma}} {{CMG}}; {{AE}} == Overview == == Diagnostic Study of Choice == === Study of choice === [Name of the investigation] is the gold standard te...")
 
No edit summary
 
(22 intermediate revisions by 2 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Pleomorphic adenoma}}
{{Pleomorphic adenoma}}
{{CMG}}; {{AE}}
{{CMG}}; {{AE}} {{M.N}}
== Overview ==
== Overview ==
[[MRI scan|MRI]] is the study of choice for pleomorphic adenoma. On T1-weighted images they show [[homogeneous]] intensity, on T2 they show marked hyperintensity reflecting myxochondroid [[stroma]] and hypointensity corresponds to [[fibrous]] [[capsule]] of the [[tumor]]. On Gd-T1 [[imaging]] it shows [[heterogeneous]] enhancement.


== Diagnostic Study of Choice ==
== Diagnostic Study of Choice ==


=== Study of choice ===
=== Study of choice ===
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
*[[MRI]] is the preferred [[diagnostic]] study of choice for pleomorphic adenoma.<ref name="RaiRohit2013">{{cite journal|last1=Rai|first1=Shalu|last2=Rohit|first2=Malik|last3=Kaur|first3=Mandeep|last4=Mukul|first4=Prabhat|title=Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report|journal=Dental Hypotheses|volume=4|issue=1|year=2013|pages=33|issn=2155-8213|doi=10.4103/2155-8213.110181}}</ref>
 
OR
 
The following result of [gold standard test] is confirmatory of [disease name]:
* [Result 1]
* [Result 2]
 
OR
 
[Name of the investigation] must be performed when:
* The patient presents with [symptom/sign 1], [symptom/sign 2], and [symptom/sign 3].
* A [name of test] is positive for [sign 1], [sign 2], and [sign 3] in the patient.
 
OR
 
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
 
OR
 
The diagnostic study of choice for [disease name] is [name of the investigation].
 
OR
 
There is no single diagnostic study of choice for the diagnosis of [disease name].  
 
OR
 
There is no single diagnostic study of choice for the diagnosis of [disease name], but [disease name] can be diagnosed based on [name of the investigation 1] and [name of the investigation 2].
 
OR
 
[Disease name] is primarily diagnosed based on the clinical presentation.
 
OR
 
Investigations:
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most specific test for the diagnosis.
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most sensitive test for diagnosis.
* Among the patients who present with clinical signs of [disease name], the [investigation name] is the most efficient test for diagnosis.


==== The comparison of various diagnostic studies for [disease name] ====
==== The comparison of various diagnostic studies for [disease name] ====
Line 55: Line 17:
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Specificity
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Specificity
|-
|-
! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 1
! style="background: #696969; color: #FFFFFF; text-align: center;" |MRI
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |43.9%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |95%
|-
! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 2
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
| style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
|}
|}
<small> [Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity</small>
<small> [Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity</small>


===== Diagnostic results =====
===== Diagnostic results =====
The following finding(s) on performing [investigation name] is(are) confirmatory for [disease name]:
======MRI======
* [Finding 1]
*[[MRI scan|MRI]] is the [[imaging]] modality of choice for pleomorphic adenoma.<ref name="pmid8881252">{{cite journal |vauthors=Ikeda K, Katoh T, Ha-Kawa SK, Iwai H, Yamashita T, Tanaka Y |title=The usefulness of MR in establishing the diagnosis of parotid pleomorphic adenoma |journal=AJNR Am J Neuroradiol |volume=17 |issue=3 |pages=555–9 |date=March 1996 |pmid=8881252 |doi= |url=}}</ref><ref name="RaiRohit2013">{{cite journal|last1=Rai|first1=Shalu|last2=Rohit|first2=Malik|last3=Kaur|first3=Mandeep|last4=Mukul|first4=Prabhat|title=Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report|journal=Dental Hypotheses|volume=4|issue=1|year=2013|pages=33|issn=2155-8213|doi=10.4103/2155-8213.110181}}</ref>
* [Finding 2]
*On T1-weighted images:
** Pleomorphic adenoma's show [[homogeneous]] intensity. <ref name="HisatomiAsaumi2003">{{cite journal|last1=Hisatomi|first1=Miki|last2=Asaumi|first2=Jun-ichi|last3=Yanagi|first3=Yoshinobu|last4=Konouchi|first4=Hironobu|last5=Matsuzaki|first5=Hidenobu|last6=Honda|first6=Yasutoshi|last7=Kishi|first7=Kanji|title=Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI|journal=Oral Oncology|volume=39|issue=6|year=2003|pages=574–579|issn=13688375|doi=10.1016/S1368-8375(03)00040-X}}</ref>
*On T2-weighted images:
**Marked hyperintensity reflects abundant myxochondroid [[stroma]].<ref name="pmid29845358">{{cite journal |vauthors=Kato H, Kawaguchi M, Ando T, Mizuta K, Aoki M, Matsuo M |title=Pleomorphic adenoma of salivary glands: common and uncommon CT and MR imaging features |journal=Jpn J Radiol |volume=36 |issue=8 |pages=463–471 |date=August 2018 |pmid=29845358 |doi=10.1007/s11604-018-0747-y |url=}}</ref>
**Hypointensity reflects the [[fibrous]] [[capsule]] of the [[tumor]].<ref name="pmid29845358">{{cite journal |vauthors=Kato H, Kawaguchi M, Ando T, Mizuta K, Aoki M, Matsuo M |title=Pleomorphic adenoma of salivary glands: common and uncommon CT and MR imaging features |journal=Jpn J Radiol |volume=36 |issue=8 |pages=463–471 |date=August 2018 |pmid=29845358 |doi=10.1007/s11604-018-0747-y |url=}}</ref>
*On Gd-T1weighted images:
**It shows [[heterogeneous]] enhancement.<ref name="HisatomiAsaumi2003">{{cite journal|last1=Hisatomi|first1=Miki|last2=Asaumi|first2=Jun-ichi|last3=Yanagi|first3=Yoshinobu|last4=Konouchi|first4=Hironobu|last5=Matsuzaki|first5=Hidenobu|last6=Honda|first6=Yasutoshi|last7=Kishi|first7=Kanji|title=Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI|journal=Oral Oncology|volume=39|issue=6|year=2003|pages=574–579|issn=13688375|doi=10.1016/S1368-8375(03)00040-X}}</ref>


===== Sequence of Diagnostic Studies =====
===== Sequence of Diagnostic Studies =====
The [name of investigation] must be performed when:
* The patient presented with symptoms/signs 1, 2, and 3 as the first step of diagnosis.
* A positive [test] is detected in the patient, to confirm the diagnosis.
OR
The various investigations must be performed in the following order:
The various investigations must be performed in the following order:
* [Initial investigation]
*[[CT]] is usually the first [[imaging]] modality of choice for pleomorphic adenoma.<ref name="RaiRohit2013">{{cite journal|last1=Rai|first1=Shalu|last2=Rohit|first2=Malik|last3=Kaur|first3=Mandeep|last4=Mukul|first4=Prabhat|title=Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report|journal=Dental Hypotheses|volume=4|issue=1|year=2013|pages=33|issn=2155-8213|doi=10.4103/2155-8213.110181}}</ref>
* [2nd investigation]
*It helps in identifying the [[lesion]] and also helps the [[physician]] in assessing the [[extension]] of the [[tumor]].
*[[MRI]] is the usually ordered investigation next after [[CT]], for an even more detailed study.<ref name="RaiRohit2013">{{cite journal|last1=Rai|first1=Shalu|last2=Rohit|first2=Malik|last3=Kaur|first3=Mandeep|last4=Mukul|first4=Prabhat|title=Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report|journal=Dental Hypotheses|volume=4|issue=1|year=2013|pages=33|issn=2155-8213|doi=10.4103/2155-8213.110181}}</ref>
*It is a [[Non-ionizing radiation|non-ionizing]] modality with excellent [[soft tissue]] distinction.
*[[FNA]] and [[biopsy]] is the definitive method of [[diagnosis]] for pleomorphic adenoma.


=== Name of Diagnostic Criteria ===
=== Name of Diagnostic Criteria ===
 
There are no established [[criteria]] for the [[diagnosis]] of pleomorphic adenoma.
'''It is recommended that you include the criteria in a table. Make sure you always cite the source of the content and whether the table has been adapted from another source.'''
 
[Disease name] is primarily diagnosed based on clinical presentation. There are no established criteria for the diagnosis of [disease name].
 
OR
 
There is no single diagnostic study of choice for [disease name], though [disease name] may be diagnosed based on [name of criteria] established by [...].
 
OR
 
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
 
OR
 
The diagnosis of [disease name] is based on the [criteria name] criteria, which includes [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
[Disease name] may be diagnosed at any time if one or more of the following criteria are met:
* Criteria 1
* Criteria 2
* Criteria 3
 
OR
 
'''IF there are clear, established diagnostic criteria'''
 
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
 
OR
 
The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
 
OR
 
'''IF there are no established diagnostic criteria'''
 
There are no established criteria for the diagnosis of [disease name].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category: Otolaryngology]]
[[Category: Medicine]]
[[Category: Oncology]]
[[Category: Surgery]]
[[Category: Up-To-Date]]

Latest revision as of 18:48, 28 January 2019

Pleomorphic adenoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pleomorphic adenoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pleomorphic adenoma diagnostic study of choice On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pleomorphic adenoma diagnostic study of choice

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pleomorphic adenoma diagnostic study of choice

CDC on Pleomorphic adenoma diagnostic study of choice

Pleomorphic adenoma diagnostic study of choice in the news

Blogs on Pleomorphic adenoma diagnostic study of choice

Directions to Hospitals Treating Pleomorphic adenoma

Risk calculators and risk factors for Pleomorphic adenoma diagnostic study of choice

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]

Overview

MRI is the study of choice for pleomorphic adenoma. On T1-weighted images they show homogeneous intensity, on T2 they show marked hyperintensity reflecting myxochondroid stroma and hypointensity corresponds to fibrous capsule of the tumor. On Gd-T1 imaging it shows heterogeneous enhancement.

Diagnostic Study of Choice

Study of choice

The comparison of various diagnostic studies for [disease name]

Test Sensitivity Specificity
MRI 43.9% 95%

[Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity

Diagnostic results
MRI
Sequence of Diagnostic Studies

The various investigations must be performed in the following order:

Name of Diagnostic Criteria

There are no established criteria for the diagnosis of pleomorphic adenoma.

References

  1. ↑ 1.0 1.1 1.2 1.3 Rai, Shalu; Rohit, Malik; Kaur, Mandeep; Mukul, Prabhat (2013). "Pleomorphic adenoma: Choice of radiographic imaging modality - Computed tomography or magnetic resonance imaging? Illustration through a case report". Dental Hypotheses. 4 (1): 33. doi:10.4103/2155-8213.110181. ISSN 2155-8213.
  2. ↑ Ikeda K, Katoh T, Ha-Kawa SK, Iwai H, Yamashita T, Tanaka Y (March 1996). "The usefulness of MR in establishing the diagnosis of parotid pleomorphic adenoma". AJNR Am J Neuroradiol. 17 (3): 555–9. PMID 8881252.
  3. ↑ 3.0 3.1 Hisatomi, Miki; Asaumi, Jun-ichi; Yanagi, Yoshinobu; Konouchi, Hironobu; Matsuzaki, Hidenobu; Honda, Yasutoshi; Kishi, Kanji (2003). "Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI". Oral Oncology. 39 (6): 574–579. doi:10.1016/S1368-8375(03)00040-X. ISSN 1368-8375.
  4. ↑ 4.0 4.1 Kato H, Kawaguchi M, Ando T, Mizuta K, Aoki M, Matsuo M (August 2018). "Pleomorphic adenoma of salivary glands: common and uncommon CT and MR imaging features". Jpn J Radiol. 36 (8): 463–471. doi:10.1007/s11604-018-0747-y. PMID 29845358.

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Pleomorphic_adenoma_diagnostic_study_of_choice&oldid=1542410"