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==Initial Laboratory Studies==
==Initial Laboratory Studies==
*There are no diagnostic laboratory findings associated with peptic ulcer disease.
*There are no diagnostic laboratory findings associated with peptic ulcer disease.
*If there is the history of peptic ulcer disease then following laboratory test can be useful:
*If there is the history of peptic ulcer disease then following laboratory test can be useful:<ref name="pmid10086037">{{cite journal |vauthors=Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE |title=Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis |journal=Postgrad Med |volume=105 |issue=3 |pages=113–6, 121–3, 127–8 passim |year=1999 |pmid=10086037 |doi=10.3810/pgm.1999.03.594 |url=}}</ref><ref name="pmid2216988">{{cite journal |vauthors=Rosen SD, Rogers AI |title=Clinical recognition and evaluation of peptic ulcer disease |journal=Postgrad Med |volume=88 |issue=5 |pages=42–7,51,55 |year=1990 |pmid=2216988 |doi= |url=}}</ref><ref name="pmid25955624">{{cite journal |vauthors=Fashner J, Gitu AC |title=Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection |journal=Am Fam Physician |volume=91 |issue=4 |pages=236–42 |year=2015 |pmid=25955624 |doi= |url=}}</ref><ref name="pmid100860372">{{cite journal |vauthors=Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE |title=Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis |journal=Postgrad Med |volume=105 |issue=3 |pages=113–6, 121–3, 127–8 passim |year=1999 |pmid=10086037 |doi=10.3810/pgm.1999.03.594 |url=}}</ref><ref name="pmid26354049">{{cite journal |vauthors=Chung CS, Chiang TH, Lee YC |title=A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers |journal=Korean J. Intern. Med. |volume=30 |issue=5 |pages=559–70 |year=2015 |pmid=26354049 |pmc=4578017 |doi=10.3904/kjim.2015.30.5.559 |url=}}</ref><ref name="pmid21263414">{{cite journal |vauthors=Mehmedović-Redzepović A, Mesihović R, Prnjavorac B, Kulo A, Merlina K |title=Hematologic and laboratory parameters in patientis with peptic ulcer bleeding treated by two modalities of endoscopic haemostasis and proton pump inhibitors |journal=Med Glas (Zenica) |volume=8 |issue=1 |pages=151–7 |year=2011 |pmid=21263414 |doi= |url=}}</ref>
*Complete blood count
**Complete blood count
*Liver function tests
**Liver function tests
*Serum lipase and amylase
**Serum lipase and amylase
*Iron studies<ref name="pmid10086037">{{cite journal |vauthors=Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE |title=Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis |journal=Postgrad Med |volume=105 |issue=3 |pages=113–6, 121–3, 127–8 passim |year=1999 |pmid=10086037 |doi=10.3810/pgm.1999.03.594 |url=}}</ref><ref name="pmid2216988">{{cite journal |vauthors=Rosen SD, Rogers AI |title=Clinical recognition and evaluation of peptic ulcer disease |journal=Postgrad Med |volume=88 |issue=5 |pages=42–7,51,55 |year=1990 |pmid=2216988 |doi= |url=}}</ref><ref name="pmid25955624">{{cite journal |vauthors=Fashner J, Gitu AC |title=Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection |journal=Am Fam Physician |volume=91 |issue=4 |pages=236–42 |year=2015 |pmid=25955624 |doi= |url=}}</ref><ref name="pmid100860372">{{cite journal |vauthors=Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE |title=Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis |journal=Postgrad Med |volume=105 |issue=3 |pages=113–6, 121–3, 127–8 passim |year=1999 |pmid=10086037 |doi=10.3810/pgm.1999.03.594 |url=}}</ref><ref name="pmid26354049">{{cite journal |vauthors=Chung CS, Chiang TH, Lee YC |title=A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers |journal=Korean J. Intern. Med. |volume=30 |issue=5 |pages=559–70 |year=2015 |pmid=26354049 |pmc=4578017 |doi=10.3904/kjim.2015.30.5.559 |url=}}</ref><ref name="pmid21263414">{{cite journal |vauthors=Mehmedović-Redzepović A, Mesihović R, Prnjavorac B, Kulo A, Merlina K |title=Hematologic and laboratory parameters in patientis with peptic ulcer bleeding treated by two modalities of endoscopic haemostasis and proton pump inhibitors |journal=Med Glas (Zenica) |volume=8 |issue=1 |pages=151–7 |year=2011 |pmid=21263414 |doi= |url=}}</ref>  
**Iron studies
*Some patients with Peptic ulcer disease may have reduced serum ferritin, which is usually suggestive of bleeding which requires further endoscopy to rule out bleeding.
**Some patients with Peptic ulcer disease may have reduced serum ferritin, which is usually suggestive of bleeding which requires further endoscopy to rule out bleeding


==References==
==References==

Revision as of 17:26, 21 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2] Manpreet Kaur, MD [3]

Overview

There is no specific diagnostic laboratory test for peptic ulcer disease but in patient with history of peptic ulcer disease, laboratory test is used to rule out bleeding.

Initial Laboratory Studies

  • There are no diagnostic laboratory findings associated with peptic ulcer disease.
  • If there is the history of peptic ulcer disease then following laboratory test can be useful:[1][2][3][4][5][6]
    • Complete blood count
    • Liver function tests
    • Serum lipase and amylase
    • Iron studies
    • Some patients with Peptic ulcer disease may have reduced serum ferritin, which is usually suggestive of bleeding which requires further endoscopy to rule out bleeding

References

  1. Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE (1999). "Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis". Postgrad Med. 105 (3): 113–6, 121–3, 127–8 passim. doi:10.3810/pgm.1999.03.594. PMID 10086037.
  2. Rosen SD, Rogers AI (1990). "Clinical recognition and evaluation of peptic ulcer disease". Postgrad Med. 88 (5): 42–7, 51, 55. PMID 2216988.
  3. Fashner J, Gitu AC (2015). "Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection". Am Fam Physician. 91 (4): 236–42. PMID 25955624.
  4. Graham DY, Rakel RE, Fendrick AM, Go MF, Marshall BJ, Peura DA, Scherger JE (1999). "Recognizing peptic ulcer disease. Keys to clinical and laboratory diagnosis". Postgrad Med. 105 (3): 113–6, 121–3, 127–8 passim. doi:10.3810/pgm.1999.03.594. PMID 10086037.
  5. Chung CS, Chiang TH, Lee YC (2015). "A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers". Korean J. Intern. Med. 30 (5): 559–70. doi:10.3904/kjim.2015.30.5.559. PMC 4578017. PMID 26354049.
  6. Mehmedović-Redzepović A, Mesihović R, Prnjavorac B, Kulo A, Merlina K (2011). "Hematologic and laboratory parameters in patientis with peptic ulcer bleeding treated by two modalities of endoscopic haemostasis and proton pump inhibitors". Med Glas (Zenica). 8 (1): 151–7. PMID 21263414.


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