Osteomyelitis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nate Michalak, B.A.,Seyedmahdi Pahlavani, M.D. [2]

Overview

The patient's history is important in establishing a diagnosis of osteomyelitis. Common history findings include intravenous drug use, bacteremia, recent open fracture or surgery, and diabetes. Common symptoms include chills, fever, malaise, local pain and warmth, edema, and erythema. Fever is typically absent in diabetic patients with osteomyelitis secondary to vascular insufficiency and in patients with infected prosthesis. The presence of a draining sinus tract is pathognomonic of chronic osteomyelitis.

History and Symptoms

Patient History

A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient based on specific types of osteomyelitis include:

  • Hematogenous Osteomyelitis:
  • Contiguous-focus Osteomyelitis:
  • Osteomyelitis secondary to vascular insufficiency:
  • Diabetes[2]
  • Diabetic patients with soft-tissue inflammation or skin ulcers in the feet

Common symptoms

  • Local:

Special Considerations

  • Diabetic patients with osteomyelitis secondary to vascular insufficiency typically do not have fever or inflammation.[5]
  • Diabetic patients with advanced neuropathy may not feel pain.
  • Fever is typically absent in patients with infected prosthesis.
  • Patients with vertebral osteomyelitis may have generalized neck and back pain.
  • The presence of a draining sinus tract is pathognomonic of chronic osteomyelitis.

References

  1. Lew, Daniel P.; Waldvogel, Francis A. (1997). "Osteomyelitis". New England Journal of Medicine. 336 (14): 999–1007. doi:10.1056/NEJM199704033361406. ISSN 0028-4793.
  2. Caputo, Gregory M.; Cavanagh, Peter R.; Ulbrecht, Jan S.; Gibbons, Gary W.; Karchmer, Adolf W. (1994). "Assessment and Management of Foot Disease in Patients with Diabetes". New England Journal of Medicine. 331 (13): 854–860. doi:10.1056/NEJM199409293311307. ISSN 0028-4793.
  3. Lew, Daniel P; Waldvogel, Francis A (2004). "Osteomyelitis". The Lancet. 364 (9431): 369–379. doi:10.1016/S0140-6736(04)16727-5. ISSN 0140-6736.
  4. Vazquez M (2002). "Osteomyelitis in children". Curr. Opin. Pediatr. 14 (1): 112–5. PMID 11880745.
  5. Newman LG, Waller J, Palestro CJ, Schwartz M, Klein MJ, Hermann G, Harrington E, Harrington M, Roman SH, Stagnaro-Green A (1991). "Unsuspected osteomyelitis in diabetic foot ulcers. Diagnosis and monitoring by leukocyte scanning with indium in 111 oxyquinoline". JAMA. 266 (9): 1246–51. PMID 1908030.