Neurofibroma surgery: Difference between revisions
Jump to navigation
Jump to search
Shanshan Cen (talk | contribs) |
Sara Mohsin (talk | contribs) |
||
| (12 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Neurofibroma}} | {{Neurofibroma}} | ||
{{CMG}}; {{AE}} {{SC}} | {{CMG}}; {{AE}}{{S.M.}} {{SC}} | ||
==Overview== | ==Overview== | ||
[[Surgery]] is the mainstay of treatment for [[neurofibroma]]. Localized and [[diffuse]] [[lesions]] are usually treated [[Surgery|surgically]]. [[Neurofibroma|Neurofibromas]] that [[Infiltration (medical)|infiltrate]] between [[nerve]] [[fascicles]] are unable to be separated from the parent [[nerve]], therefore, deep-seated [[lesions]] are often [[Managed Care|managed]] conservatively. Local [[Recurrence plot|recurrence]] after [[excision]] is uncommon .and [[malignant transformation]] occurs [[Rare|rarely]]. | |||
==Surgery== | ==Surgery== | ||
'''Localised neurofibroma | '''Localised neurofibroma and Diffuse neurofibroma (not associated with NF-1)''' | ||
* | * Localized and [[diffuse]] [[lesions]] are usually treated [[Surgery|surgically]]<ref name="radio">Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015 </ref> | ||
* Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively | * [[Neurofibroma|Neurofibromas]] that [[Infiltration (medical)|infiltrate]] between [[nerve]] [[fascicles]] are unable to be separated from the parent [[nerve]], therefore, deep-seated [[lesions]] are often [[Managed Care|managed]] conservatively | ||
* Local recurrence after excision is uncommon | * Local [[Recurrence plot|recurrence]] after [[excision]] is uncommon | ||
* [[malignant transformation]] occurs [[Rare|rarely]] | |||
'''Plexiform neurofibroma''' | '''Plexiform neurofibroma (NF-1 associated)''' | ||
* The primary treatment option for [[plexiform neurofibroma]] is [[surgery]] | * The primary treatment option for [[plexiform neurofibroma]] is not [[surgery|surgery,]] until and unless: | ||
* Removal of plexiform | **Debilitating [[symptoms]] are present | ||
**There is a [[Possibility theory|possibility]] of [[malignant transformation]]<ref>{{cite journal |vauthors=Packer RJ, Gutmann DH, Rubenstein A, etal |title=Plexiform neurofibromas in NF1: toward biologic-based therapy |journal=Neurology |volume=58 |issue=10 |pages=1461–70 |date=May 2002 |pmid=12041525 |url=http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12041525 |doi=10.1212/wnl.58.10.1461}}</ref><ref name="radio" /> | |||
* Removal of [[plexiform neurofibroma]]s is difficult because they can be large and cross [[tissue]] boundaries hence, leading to incomplete [[resection]] | |||
* [[Recurrence plot|Recurrence]] after [[resection]] is frequent | |||
* Recurrence after resection is frequent | |||
==References== | ==References== | ||
| Line 27: | Line 28: | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Neurology]] | |||
[[Category:Neurosurgery]] | |||
Latest revision as of 01:31, 29 April 2019
|
Neurofibroma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Neurofibroma surgery On the Web |
|
American Roentgen Ray Society Images of Neurofibroma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Shanshan Cen, M.D. [3]
Overview
Surgery is the mainstay of treatment for neurofibroma. Localized and diffuse lesions are usually treated surgically. Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively. Local recurrence after excision is uncommon .and malignant transformation occurs rarely.
Surgery
Localised neurofibroma and Diffuse neurofibroma (not associated with NF-1)
- Localized and diffuse lesions are usually treated surgically[1]
- Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively
- Local recurrence after excision is uncommon
- malignant transformation occurs rarely
Plexiform neurofibroma (NF-1 associated)
- The primary treatment option for plexiform neurofibroma is not surgery, until and unless:
- Debilitating symptoms are present
- There is a possibility of malignant transformation[2][1]
- Removal of plexiform neurofibromas is difficult because they can be large and cross tissue boundaries hence, leading to incomplete resection
- Recurrence after resection is frequent
References
- ↑ 1.0 1.1 Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015
- ↑ Packer RJ, Gutmann DH, Rubenstein A, et al. (May 2002). "Plexiform neurofibromas in NF1: toward biologic-based therapy". Neurology. 58 (10): 1461–70. doi:10.1212/wnl.58.10.1461. PMID 12041525.