Neonatal jaundice causes: Difference between revisions
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| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
| bgcolor="Beige" | [[Losartan and Hydrochlorothiazide|Losartan]], [[Losartan and Hydrochlorothiazide|Hydrochlorothiazide]] | | bgcolor="Beige" | [[Losartan and Hydrochlorothiazide|Losartan]], [[Losartan and Hydrochlorothiazide|Hydrochlorothiazide]] | ||
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| '''Genetic''' | | '''Genetic''' | ||
| bgcolor="Beige" | [[Cystic fibrosis]], [[Alpha-1-antitrypsin deficiency]] | | bgcolor="Beige" | [[Cystic fibrosis]], [[Alpha-1-antitrypsin deficiency]] | ||
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| '''Pulmonary''' | | '''Pulmonary''' | ||
| bgcolor="Beige" | [[Alpha-1-antitrypsin deficiency]] | | bgcolor="Beige" | [[Alpha-1-antitrypsin deficiency]] | ||
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Revision as of 19:40, 15 February 2018
Neonatal jaundice Microchapters |
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Treatment |
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Neonatal jaundice causes On the Web |
American Roentgen Ray Society Images of Neonatal jaundice causes |
Risk calculators and risk factors for Neonatal jaundice causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Neonatal jaundice is caused by hemolysis of the RBCs mainly due to either intravascular causes or extravascular causes. Other causes include non-hemolytic causes such as cephalosporin induced jaundice, genetic mutations of the UGT enzyme, and hepatic causes.
Causes
Common causes
- Common causes of neonatal jaundice include the following:[1][2]
- Increase bilirubin production due to hemolysis. Hemolytic causes include:
- Intrinsic causes of hemolysis
- Systemic contitions
- Enzyme conditions
- Globin synthesis defect
- Extrinsic causes of hemolysis
- Alloimmunity (The neonatal or cord blood gives a positive direct Coombs test and the maternal blood gives a positive indirect Coombs test)
- Hemolytic disease of the newborn (ABO)
- Rh disease
- Increase bilirubin production due to hemolysis. Hemolytic causes include:
Less common causes
- Hepatic causes
- Infections
- Metabolic
- Drugs:
- Total parenteral nutrition
- Post-hepatic
- Bile duct obstruction
Causes by Organ System
Cardiovascular | No underlying causes |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | Losartan, Hydrochlorothiazide |
Ear Nose Throat | No underlying causes |
Endocrine | Hypothyroidism |
Environmental | No underlying causes |
Gastroenterologic | Gilbert's syndrome, Crigler-Najjar syndrome, Alpha-1-antitrypsin deficiency, Biliary atresia, Bile duct obstruction |
Genetic | Cystic fibrosis, Alpha-1-antitrypsin deficiency |
Hematologic | Cephalhematoma, Polycythemia |
Iatrogenic | No underlying causes |
Infectious Disease | Sepsis, Hepatitis B, TORCH infections |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | No underlying causes |
Nutritional/Metabolic | Galactosemia, Total parenteral nutrition |
Obstetric/Gynecologic | No underlying causes |
Oncologic | No underlying causes |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | Alpha-1-antitrypsin deficiency |
Renal/Electrolyte | No underlying causes |
Rheumatology/Immunology/Allergy | No underlying causes |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | No underlying causes |
Causes in Alphabetical Order
The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3References
- ↑ Poland, R L (1980). "High milk lipase activity associated with breastmilk jaundice". Pediatr Res. 14: 1328–31. Unknown parameter
|coauthors=
ignored (help) - ↑ Murphy, J F (1981). "Pregnanediols and breast-milk jaundice". Arch Dis Child. 56: 474–76. Unknown parameter
|coauthors=
ignored (help) - ↑ Kumral, A (2009). "Breast milk jaundice correlates with high levels of epidermal growth factor". Pediatr Res. 66: 218–21. Unknown parameter
|coauthors=
ignored (help) - ↑ Arias, IM (1964). "Prolonged neonatal unconjugated hyperbilirubinemia associated with breast feeding and a steroid, pregnane-3(alpha), 20(beta)-diol in maternal milk that inhibits glucuronide formation in vitro". J Clin Invest. 43: 2037–47. Unknown parameter
|coauthors=
ignored (help)