Myxoma causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The main cause of cardiac myxoma remains unknown. However, in some cases like inherited myxomatosis there is a strong relation with genetic mutations of PRKAR1A gene.

Causes

  • There are no established causes for cardiac myxoma.[1][2]
  • About 10% of cardiac myxomas are familial.
  • Inherited myxomatosis is caused by a mutation in the PRKAR1A gene.


References

  1. Messina F, Romano P, Crosca S (2015). "Atrial myxomas and different clinical presentations". Int. J. Cardiol. doi:10.1016/j.ijcard.2015.08.063. PMID 26442965.
  2. Amano J, Kono T, Wada Y, Zhang T, Koide N, Fujimori M, Ito K (2003). "Cardiac myxoma: its origin and tumor characteristics". Ann Thorac Cardiovasc Surg. 9 (4): 215–21. PMID 13129418.


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