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{{Infobox_Disease |
  Name          = {{PAGENAME}} |
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  DiseasesDB    = 22895 |
  ICD10          = {{ICD10|M|79|1|m|70}} |
  ICD9          = {{ICD9|729.1}} |
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  OMIM          = |
  MedlinePlus    = |
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{{Myalgia}}
{{Myalgia}}
{{CMG}}
{{CMG}}


==Overview==
{{SK}} Muscle pain; myodynia
'''Myalgia''' means "[[muscle]] [[Pain and nociception|pain]]" and is a symptom of many diseases and disorders. The most common cause for myalgia is either overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to [[virus|viral infection]]s. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or [[chronic fatigue syndrome]].
== [[Myalgia overview|Overview]] ==


==Differential diagnosis of causes of myalgia==
== [[Myalgia pathophysiology|Pathophysiology]] ==
The most common causes of myalgia are overuse, [[injury]] or [[Stress (medicine)|stress]]<ref name=MedlinePlus> [http://www.nlm.nih.gov/medlineplus/ency/article/003178.htm MedlinePlus]</ref>. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.


===Overuse===
== [[Myalgia causes|Causes]] ==
Overuse of a muscle is using it too much, too soon and/or too often. <ref name=MedlinePlus/>  Examples are:
*[[Repetitive strain injury]].


===Injury===
== [[Myalgia differential diagnosis|Differentiating Myalgia from other Diseases]]==
The most common causes of myalgia by [[injury]] are: sprains and strain (injury)<ref name=MedlinePlus/>.


===Diseases/Disorders===
== [[Myalgia natural history, complications and prognosis|Natural History, Complications and Prognosis]] ==


====Infectious====
== Diagnosis ==
[[Trichinosis]], [[Typhoid fever]], [[Upper respiratory tract infection]], [[Viral pneumonia]], [[Influenza]], [[Common cold]], [[Community-acquired pneumonia]], [[Coccidioidomycosis]], [[Dengue]], [[Endemic typhus]], [[HIV]], [[Infectious mononucleosis]], [[Legionellosis]], [[Leptospirosis]], [[Lyme disease]], [[Malaria]], [[Marburg virus]], [[Meningitis]], [[Monkeypox]], [[Pharyngitis]], [[Pneumonia]], [[Prostatitis]], [[Psittacosis]], [[Q fever]], [[Rabies]],  [[Rift Valley fever]], [[Severe acute respiratory syndrome]] (SARS), [[Toxic shock syndrome]], West Nile, [[Chikungunya]]


====Autoimmune====
[[Myalgia history and symptoms|History and Symptoms]] | [[Myalgia physical examination|Physical Examination]] | [[Myalgia laboratory findings|Laboratory Findings]] | [[Myalgia CT|CT]] | [[Myalgia MRI|MRI]] | [[Myalgia other imaging findings|Other Imaging Studies]] | [[Myalgia other diagnostic studies|Other Diagnostic Studies]]
[[Multiple sclerosis]], [[Myositis]], [[Lupus erythematosus]], [[Familial Mediterranean fever]], [[Polyarteritis nodosa]], [[Devic's disease]], [[Morphea]]


====Metabolic defect====
== Treatment ==
[[Carnitine palmitoyltransferase II deficiency]], [[Conn's syndrome]], [[Adrenal insufficiency]]


====Other====
[[Myalgia medical therapy|Medical Therapy]] | [[Myalgia surgery|Surgery]] | [[Myalgia primary prevention| Primary Prevention]] | [[Myalgia secondary prevention|Secondary Prevention]]
[[Chronic fatigue syndrome]], [[Hypokalemia]], [[Exercise intolerance]], [[Mastocytosis]], [[Peripheral neuropathy]], Eosinophilia myalgia syndrome, [[Fibromyalgia]], [[Barcoo Fever]], [[Delayed onset muscle soreness]]


===Medications===
==Related Chapters==
Aldara, [[Acrylamide]], [[Darbepoetin]], [[Isotretinoin]], [[Procainamide]], [[Quinupristin/dalfopristin]], Spiriva, [[Sumatriptan]], [[Vardenafil]], [[Statins]], Zetia, Zomig, Boniva
 
===As a Response to Vaccination===
A moderate occurrence (25-35%) of myalgia in recipients of [[tetanus]] [[vaccination]] is identified in the US; it presents in the large muscle groups and at the subcutaneous injection site.  When a patient returns with these symptoms (which include [[fever]], poor [[appetite]] and [[lethargy]]), a clinician who fails to notice the recent tetanus vaccination on the patient's chart is in danger of making a life-threatening misdiagnosis.
: An item of note is that in heart patients using selective β<sub>1</sub>-blockers such as [[metoprolol]], incidence of myalgia after tetanus vaccination is significantly higher.
 
===Withdrawal Syndromes===
Sudden cessation of [[opioids]], [[barbiturates]], [[benzodiazepines]], or [[alcohol]] can induce myalgia.
 
==Myalgia Video==
*[http://surgery-videoz.blogspot.com/2007/11/myalgia.html Video on Myalgia]
 
==Related chapters==
* [[Delayed onset muscle soreness]]
* [[Delayed onset muscle soreness]]
* [[Myopathy]]
* [[Myopathy]]
* [[Myelitis]]
* [[Myelitis]]


==Resources==
* [http://www.neuro.wustl.edu/neuromuscular/mother/mpain.html NEUROMUSCULAR DISEASE CENTER Washington University]


{{Diseases of the musculoskeletal system and connective tissue}}
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Latest revision as of 22:49, 29 July 2020