Multiple sclerosis surgery: Difference between revisions

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[[Surgery]] is not the [[first-line treatment]] option for patients with multiple sclerosis but can be helpful in managing some [[Symptom|symptoms]]:
[[Surgery]] is not the [[first-line treatment]] option for patients with multiple sclerosis but can be helpful in managing some [[Symptom|symptoms]]:
===Trigeminal Neuralgia===
====Trigeminal neuralgia====
If we fail to treat trigeminal neuralgia with medication, surgery can be an option. In order to reduce pain transmission to brain we can apply more damage to the nerve and reduce this transmission.<ref>{{cite journal |author=Kondziolka D, Lunsford LD, Bissonette DJ |title=Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia |journal=The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques |volume=21 |issue=2 |pages=137-40 |year=1994 |pmid=8087740 |doi=}}</ref>
If we fail to treat trigeminal neuralgia with medication, surgery can be an option. In order to reduce pain transmission to brain we can apply more damage to the nerve and reduce this transmission.<ref>{{cite journal |author=Kondziolka D, Lunsford LD, Bissonette DJ |title=Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia |journal=The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques |volume=21 |issue=2 |pages=137-40 |year=1994 |pmid=8087740 |doi=}}</ref>
===Tremor and Ataxia===
====Tremor and Ataxia====
If all these measures fail some patients are candidates for [[thalamus]] [[surgery]]. This kind of surgery can be both a [[thalamotomy]] or the implantation of a [[thalamic stimulator]]. Complications are frequent (30% in thalamotomy and 10% in deep brain stimulation) and include a worsening of ataxia, [[dysarthria]] and [[hemiparesis]].
Using [[surgery]] for treatment of [[tremor]] and [[ataxia]] include [[thalamotomy]] and implantation of a [[thalamic stimulator]]. Evidence shows that [[thalamotomy]] is more effective but because of more serious [[side effects]] brain stimulation is more preferable.<ref>{{cite journal |author=Bittar RG, Hyam J, Nandi D, Wang S, Liu X, Joint C, Bain PG, Gregory R, Stein J, Aziz TZ|title=Thalamotomy versus thalamic stimulation for multiple sclerosis tremor |journal=Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia |volume=12 |issue=6 |pages=638-42 |year=2005 |pmid=16098758|doi=10.1016/j.jocn.2004.09.008}}</ref>
 
Thalamotomy is a more efficacious surgical treatment for intractable MS tremor, however the higher incidence of persistent neurological deficits in patients receiving lesional surgery supports the use of deep brain stimulation as the preferred surgical strategy.<ref>{{cite journal |author=Bittar RG, Hyam J, Nandi D, Wang S, Liu X, Joint C, Bain PG, Gregory R, Stein J, Aziz TZ|title=Thalamotomy versus thalamic stimulation for multiple sclerosis tremor |journal=Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia |volume=12 |issue=6 |pages=638-42 |year=2005 |pmid=16098758|doi=10.1016/j.jocn.2004.09.008}}</ref>


==References==
==References==

Revision as of 20:21, 3 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Surgery

Surgery is not the first-line treatment option for patients with multiple sclerosis but can be helpful in managing some symptoms:

Trigeminal neuralgia

If we fail to treat trigeminal neuralgia with medication, surgery can be an option. In order to reduce pain transmission to brain we can apply more damage to the nerve and reduce this transmission.[1]

Tremor and Ataxia

Using surgery for treatment of tremor and ataxia include thalamotomy and implantation of a thalamic stimulator. Evidence shows that thalamotomy is more effective but because of more serious side effects brain stimulation is more preferable.[2]

References

  1. Kondziolka D, Lunsford LD, Bissonette DJ (1994). "Long-term results after glycerol rhizotomy for multiple sclerosis-related trigeminal neuralgia". The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 21 (2): 137–40. PMID 8087740.
  2. Bittar RG, Hyam J, Nandi D, Wang S, Liu X, Joint C, Bain PG, Gregory R, Stein J, Aziz TZ (2005). "Thalamotomy versus thalamic stimulation for multiple sclerosis tremor". Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 12 (6): 638–42. doi:10.1016/j.jocn.2004.09.008. PMID 16098758.

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