Multiple sclerosis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

MRI

On MRI, multiple sclerosis is characterized by cerebral and/or spinal cord plaques which are demyelinating areas.[1] These lesions are commonly ovoid, and located in periventricular white matter, cerebellum and brain stem.[2]


Patient #1

Images courtesy of RadsWiki

Patient #2: Contrast enchancement of several lesions indicates active disease

Images courtesy of RadsWiki

References

  1. Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mörk S, Bö L (January 1998). "Axonal transection in the lesions of multiple sclerosis". N. Engl. J. Med. 338 (5): 278–85. doi:10.1056/NEJM199801293380502. PMID 9445407.
  2. Fazekas F, Barkhof F, Filippi M, Grossman RI, Li DK, McDonald WI, McFarland HF, Paty DW, Simon JH, Wolinsky JS, Miller DH (August 1999). "The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis". Neurology. 53 (3): 448–56. PMID 10449103.

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