Multiple endocrine neoplasia type 2 diagnostic criteria
{{}} Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; {{AE} Ammu Susheela, M.D. [2]
Overview
Diagnostic Criteria
The current clinical criteria for detecting Multiple endocrine neoplasia type 2 is as follows:[1]
| Clinical criteria for diagnosis of Multiple endocrine neoplasia type 2 |
|---|
| 2 or more specific endocrine tumors (medullary thyroid carcinoma, pheochromocytoma or parathyroid hyperplasia) |
| Familial medullary thyroid carcinoma is diagnosed in families with four or more cases of medullary thryoid cacrinoma without pheochromocytoma and parathyroid adenoma |
| Multiple endocrine neoplasia type 2b is diagnosed if there is early onset of medullary throid carcinoma, mucosal neuromas of lips and tongue, disctinctive facial features with enlarged lips and marfanoid body habitus |