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==Overview==
==Overview==
 
Symptoms of MERS-CoV typically include high-grade [[fever]], [[cough]], [[headache]], [[dyspnea]], and [[myalgia]]. Gastrointestinal symptoms such as [[diarrhea]], [[vomiting]], and [[abdominal pain]] may also be present.
The most common symptoms at presentation include [[fever]], with or without [[chills]] or [[rigors]], [[cough]], [[shortness of breath]], and [[myalgia]]. Gastrointestinal symptoms such as [[diarrhea]], [[vomiting]], or [[abdominal pain]] are also frequent. [[Acute kidney injury]], [[pericarditis]], and [[disseminated intravascular coagulation]] and other serious complications may occur in some cases.


==History and Symptoms==
==History and Symptoms==
Most patients present with [[fever]], [[chills]], [[headache]], non-productive [[cough]], [[dyspnea]], and [[myalgia]]. Other symptoms can include [[sore throat]], [[coryza]], [[sputum]] production, [[dizziness]], [[nausea]] and [[vomiting]], [[diarrhea]], and [[abdominal pain]]. Atypical presentations including mild respiratory illness without [[fever]] and with [[diarrhea]] preceding the development of pneumonia have been reported. The table below describes the [[symptoms]] of [[MERS-CoV]] [[infection]].<ref name="pmid23891402">{{cite journal| author=Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A et al.| title=Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 752-61 | pmid=23891402 | doi=10.1016/S1473-3099(13)70204-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23891402  }} </ref>
*The majority of patients infected with MERS-CoV present with high-grade [[fever]], [[headache]], non-productive [[cough]], [[dyspnea]], and [[myalgia]]. Other symptoms include [[sore throat]], [[coryza]], [[sputum]] production, [[dizziness]], [[nausea]] and [[vomiting]], [[diarrhea]], and [[abdominal pain]].
*Atypical presentations, such afebrile mild respiratory illnesses with [[diarrhea]] preceding the development of pneumonia, have been reported.  
*The table below lists the [[symptoms]] of MERS-CoV infection:<ref name="pmid23891402">{{cite journal| author=Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A et al.| title=Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 752-61 | pmid=23891402 | doi=10.1016/S1473-3099(13)70204-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23891402  }} </ref>


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! style="padding: 0 5px; width: 50px; background: #4479BA; font-weight: bold;" | {{fontcolor|#FFFFFF|Percentage}}
! style="padding: 0 5px; width: 50px; background: #4479BA; font-weight: bold;" | {{fontcolor|#FFFFFF|Percentage}}
|-
|-
| style="padding: 0 5px; background: #DCDCDC;" | [[Fever]] <br>&nbsp;&nbsp;&nbsp;[[Fever]] with [[chills]] or [[rigors]]
| style="padding: 0 5px; background: #DCDCDC;" | [[Fever]]
| style="padding: 0 5px; background: #F5F5F5;" | 98% <br>&nbsp;&nbsp;&nbsp;87%
| style="padding: 0 5px; background: #F5F5F5;" | 98%
|-
|-
| style="padding: 0 5px; background: #DCDCDC;" | [[ Cough]] <br>&nbsp;&nbsp;&nbsp;[[dry cough|Dry]] <br>&nbsp;&nbsp;&nbsp;[[productive cough|Productive]]
| style="padding: 0 5px; background: #DCDCDC;" | [[ Cough]]
| style="padding: 0 5px; background: #F5F5F5;" | 83% <br>&nbsp;&nbsp;&nbsp;47% <br>&nbsp;&nbsp;&nbsp;36%
| style="padding: 0 5px; background: #F5F5F5;" | 83%
|-
|-
| style="padding: 0 5px; background: #DCDCDC;" | [[Hemoptysis]]
| style="padding: 0 5px; background: #DCDCDC;" | [[Hemoptysis]]
| style="padding: 0 5px; background: #F5F5F5;" | 17%
| style="padding: 0 5px; background: #F5F5F5;" | 17%
|-
|-
| style="padding: 0 5px; background: #DCDCDC;" | [[Shortness of breath]]
| style="padding: 0 5px; background: #DCDCDC;" | [[Dyspnea]]
| style="padding: 0 5px; background: #F5F5F5;" | 72%
| style="padding: 0 5px; background: #F5F5F5;" | 72%
|-
|-
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| style="padding: 0 5px; background: #F5F5F5;" | 21%
| style="padding: 0 5px; background: #F5F5F5;" | 21%
|-
|-
| style="padding: 0 5px; background: #DCDCDC;" | [[Diarrhoea]]
| style="padding: 0 5px; background: #DCDCDC;" | [[Diarrhea]]
| style="padding: 0 5px; background: #F5F5F5;" | 26%
| style="padding: 0 5px; background: #F5F5F5;" | 26%
|-
|-

Revision as of 12:50, 16 June 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Symptoms of MERS-CoV typically include high-grade fever, cough, headache, dyspnea, and myalgia. Gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain may also be present.

History and Symptoms

Symptom Percentage
Fever 98%
Cough 83%
Hemoptysis 17%
Dyspnea 72%
Chest Pain 15%
Sore throat 21%
Runny nose 4%
Abdominal Pain 17%
Nausea 21%
Vomiting 21%
Diarrhea 26%
Myalgia 32%
Headache 13%

References

  1. Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A; et al. (2013). "Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study". Lancet Infect Dis. 13 (9): 752–61. doi:10.1016/S1473-3099(13)70204-4. PMID 23891402.

See Also