Middle East respiratory syndrome coronavirus infection historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
*The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. | *The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. The index patient was a middle-aged man who presented with pneumonia and acute kidney injury. | ||
*The virus was first termed human coronavirus-EMC (Erasmus Medical Center). | |||
* On June 13 2012, Egyptian virologist, Dr. Ali Mohamed Zaki, identified the [[coronavirus]] responsible for the syndrome in Saudi Arabia.<ref name="pmid23075143">{{cite journal| author=Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA| title=Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. | journal=N Engl J Med | year= 2012 | volume= 367 | issue= 19 | pages= 1814-20 | pmid=23075143 | doi=10.1056/NEJMoa1211721 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23075143 }} </ref> | * On June 13 2012, Egyptian virologist, Dr. Ali Mohamed Zaki, identified the [[coronavirus]] responsible for the syndrome in Saudi Arabia.<ref name="pmid23075143">{{cite journal| author=Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA| title=Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. | journal=N Engl J Med | year= 2012 | volume= 367 | issue= 19 | pages= 1814-20 | pmid=23075143 | doi=10.1056/NEJMoa1211721 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23075143 }} </ref> | ||
*On September 2012, the virus was first reported outside Saudi Arabia in a 44 year old man | *On September 2012, the virus was first reported outside Saudi Arabia in Qatar in a 44 year old man who had recently traveled to Saudi Arabia. | ||
*It was determined | *It was later determined that [[viruses]] from the EMC/2012 and England/Qatar/2012, date to early 2011, suggesting that these cases had likely descended from a single [[zoonotic]] event.<ref name="pmid23693015">{{cite journal| author=Cotten M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P et al.| title=Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus. | journal=Emerg Infect Dis | year= 2013 | volume= 19 | issue= 5 | pages= 736-42B | pmid=23693015 | doi=10.3201/eid1905.130057 | pmc=PMC3647518 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23693015 }} </ref> | ||
*During the 2012-2013 outbreak, the [[World Health Organization]] ([[WHO]]) International Health Regulations Emergency Committee determined that [[MERS-CoV]] did not meet the criteria for a "public health emergency of international concern", but was nevertheless of "serious and of great concern". | *During the 2012-2013 outbreak, the [[World Health Organization]] ([[WHO]]) International Health Regulations Emergency Committee determined that [[MERS-CoV]] did not meet the criteria for a "public health emergency of international concern", but was nevertheless of "serious and of great concern". | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 14:42, 12 June 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2], João André Alves Silva, M.D. [3]
Overview
The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. Dr. Ali Mohamed Zaki, an Egyptian virologist, was the first to attribute MERS-CoV to coronavirus.
Historical Perspective
- The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. The index patient was a middle-aged man who presented with pneumonia and acute kidney injury.
- The virus was first termed human coronavirus-EMC (Erasmus Medical Center).
- On June 13 2012, Egyptian virologist, Dr. Ali Mohamed Zaki, identified the coronavirus responsible for the syndrome in Saudi Arabia.[1]
- On September 2012, the virus was first reported outside Saudi Arabia in Qatar in a 44 year old man who had recently traveled to Saudi Arabia.
- It was later determined that viruses from the EMC/2012 and England/Qatar/2012, date to early 2011, suggesting that these cases had likely descended from a single zoonotic event.[2]
- During the 2012-2013 outbreak, the World Health Organization (WHO) International Health Regulations Emergency Committee determined that MERS-CoV did not meet the criteria for a "public health emergency of international concern", but was nevertheless of "serious and of great concern".
References
- ↑ Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA (2012). "Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia". N Engl J Med. 367 (19): 1814–20. doi:10.1056/NEJMoa1211721. PMID 23075143.
- ↑ Cotten M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P; et al. (2013). "Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus". Emerg Infect Dis. 19 (5): 736–42B. doi:10.3201/eid1905.130057. PMC 3647518. PMID 23693015.