Mediastinitis: Difference between revisions

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==Overview==
== [[Mediastinitis overview|Overview]] ==


'''Mediastinitis''' is [[inflammation]] of the tissues in the mid-chest, or [[mediastinum]].  It can be either [[Acute (medical)|acute]] or [[Chronic (medicine)|chronic]].
== [[Mediastinitis historical perspective|Historical Perspective]] ==


Acute mediastinitis is usually bacterial and due to rupture of organs in the mediastinum. As the infection can progress rapidly, this is considered a serious condition.  Chronic [[sclerosis|sclerosing]] (or [[fibrosis|fibrosing]]) mediastinitis, while potentially serious, is caused by a long-standing inflammation of the mediastinum, leading to growth of acellular collagen and fibrous tissue within the chest and around the central vessels and airways.  It has a different cause, treatment, and prognosis than acute infectious mediastinitis.
== [[Mediastinitis pathophysiology|Pathophysiology]] ==


==Causes==
== [[Mediastinitis causes|Causes]] ==
===Acute===
*In modern practice, most cases of acute mediastinitis result from [[Complication (medicine)|complications]] of cardiovascular or endoscopic surgical procedures. 
*[[Dental caries|Odontogenic]] (infected tooth)
*Perforation of the esophagus ([[Boerhaave syndrome]])
*[[Retropharyngeal space|Retropharyngeal]] infections


===Chronic===
== [[Mediastinitis differential diagnosis|Differentiating Mediastinitis from other Diseases]] ==
Chronic medistinitis is usually a radiologic diagnosis manifested by diffuse fibrosis of the soft tissues of the mediastinum.  This is sometimes the consequence of prior granulomatous disease, most commonly [[histoplasmosis]].  Other identifiable causes include [[tuberculosis]] and [[radiation]] therapy.  Fibrosing mediastinitis most frequently causes problems by constricting blood vessels or airways in the mediastinum.  This may result in such complications as [[superior vena cava syndrome]] or [[pulmonary edema]] from compression of pulmonary veins. 


==Treatment==
== [[Mediastinitis epidemiology and demographics|Epidemiology and Demographics]] ==
Treatment for chronic fibrosing mediastinitis is somewhat controversial, and may include steroids or surgical decompression of affected vessels.
 
== [[Mediastinitis risk factors|Risk Factors]] ==
 
== [[Mediastinitis natural history, complications and prognosis|Natural History, Complications and Prognosis]] ==
 
== Diagnosis ==
[[Mediastinitis history and symptoms|History and Symptoms]] | [[Mediastinitis physical examination|Physical Examination]] | [[Mediastinitis laboratory tests|Laboratory Findings]] | [[Mediastinitis electrocardiogram|Electrocardiogram]] | [[Mediastinitis chest x ray|Chest X Ray]] | [[Mediastinitis CT|CT]] | [[Mediastinitis MRI|MRI]] | [[Mediastinitis other imaging findings|Other Imaging Findings]] | [[Mediastinitis other diagnostic studies|Other Diagnostic Studies]]
 
== Treatment ==
[[Mediastinitis medical therapy|Medical Therapy]] | [[Mediastinitis surgery|Surgery]] | [[Mediastinitis primary prevention|Primary Prevention]] | [[Mediastinitis secondary prevention|Secondary Prevention]] | [[Mediastinitis cost-effectiveness of therapy| Cost-Effectiveness of Therapy]] | [[Mediastinitis future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Mediastinitis case study one|Case #1]]


{{Respiratory pathology}}
{{Respiratory pathology}}

Revision as of 20:05, 25 September 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Mediastinitis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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