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==Overview== | ==Overview== | ||
When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include the review of common associated conditions such as ''[[Helicobacter|H. pyroli]]'' associated gastritis and autoimmune disorders, such as [[Hashimoto's thyroiditis]], [[Sjogren’s syndrome]], and [[Celiac disease]]. | When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include the review of common associated conditions such as ''[[Helicobacter|H. pyroli]]'' associated gastritis and autoimmune disorders, such as [[Hashimoto's thyroiditis]], [[Sjogren’s syndrome]], and [[Celiac disease]]. Symptoms of MALT lymphoma depend on the location of the tumor: '''gastric''' and '''non gastric'''. Symptoms of MALT lymphoma include [[pigastric pain|epigastric pain]], [[fatigue]], [[heartburn]], [[fever]], [[cough]] with [[hemoptysis|blood in sputum]], [[dyspnea|shortness of breath]], and/or [[Orbital mass causes|lump in the superior lateral quadrant of the orbit]], [[breast]], [[neck]], or [[salivary gland]]. | ||
==History== | ==History== | ||
*When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include: | *When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include:<ref name="KinkadeEsan2015">{{cite journal|last1=Kinkade|first1=Zoe|last2=Esan|first2=Olukemi A.|last3=Rosado|first3=Flavia G.|last4=Craig|first4=Michael|last5=Vos|first5=Jeffrey A.|title=Ileal mucosa-associated lymphoid tissue lymphoma presenting with small bowel obstruction: a case report|journal=Diagnostic Pathology|volume=10|issue=1|year=2015|issn=1746-1596|doi=10.1186/s13000-015-0353-6}}</ref> | ||
:*Review of common associated conditions such as ''[[Helicobacter|H. pyroli]]'' associated gastritis and autoimmune disorders, such as [[Hashimoto's thyroiditis]], [[Sjogren’s syndrome]], and [[Celiac disease]] | :*Review of common associated conditions such as ''[[Helicobacter|H. pyroli]]'' associated gastritis and autoimmune disorders, such as [[Hashimoto's thyroiditis]], [[Sjogren’s syndrome]], and [[Celiac disease]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2], Ahmed Younes M.B.B.CH [3]
Overview
When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include the review of common associated conditions such as H. pyroli associated gastritis and autoimmune disorders, such as Hashimoto's thyroiditis, Sjogren’s syndrome, and Celiac disease. Symptoms of MALT lymphoma depend on the location of the tumor: gastric and non gastric. Symptoms of MALT lymphoma include epigastric pain, fatigue, heartburn, fever, cough with blood in sputum, shortness of breath, and/or lump in the superior lateral quadrant of the orbit, breast, neck, or salivary gland.
History
- When evaluating a patient for MALT lymphoma, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include:[1]
- Review of common associated conditions such as H. pyroli associated gastritis and autoimmune disorders, such as Hashimoto's thyroiditis, Sjogren’s syndrome, and Celiac disease
Symptoms
Symptoms of MALT lymphoma depend on the location of the tumor: gastric and non gastric.[2]
Gastric MALT Lymphoma
Non Gastric MALT Lymphoma
1) MALT Lymphoma of the Lung
- Symptoms of MALT lymphoma of the lung include:[4]
- Most of the cases are asymptomatic
- Cough with blood in sputum
- Shortness of breath
- Fever
- Weight loss
2) MALT Lymphoma of the Orbit
- Symptoms of MALT lymphoma of the orbit include:[5]
- Lump in the superior lateral quadrant of the orbit
- Drooping of the eyelids
- Double vision
- Abnormal ocular movements
- "Salmon red patch" of swollen conjunctiva (25%)
3) MALT Lymphoma of the Skin
- Symptoms of MALT lymphoma of the skin include:[4]
- Single to multiple red–brown lumps or flat, discoloured areas on the back or extremities, can be itchy
4) MALT Lymphoma of the Bowel
- Symptoms of MALT lymphoma of the bowel include:[4]
5) MALT Lymphoma of the Urinary Tract
- Symptoms of MALT lymphoma of the urinary tract include:[4]
6) MALT Lymphoma of the Breast
- Symptoms of MALT lymphoma of the breast include:[4]
7) MALT Lymphoma of the Thyroid
- Symptoms of MALT lymphoma of the thyroid gland include:[4]
- Lump in the neck
- Difficulty swallowing
- Hoarseness in voice
8) MALT Lymphoma of the Salivary Gland
- Symptoms of MALT lymphoma of the salivary gland include:[4]
- Lump in the salivary gland (i.e., in front of the ear or at the angle of the jaw)
References
- ↑ Kinkade, Zoe; Esan, Olukemi A.; Rosado, Flavia G.; Craig, Michael; Vos, Jeffrey A. (2015). "Ileal mucosa-associated lymphoid tissue lymphoma presenting with small bowel obstruction: a case report". Diagnostic Pathology. 10 (1). doi:10.1186/s13000-015-0353-6. ISSN 1746-1596.
- ↑ 2.0 2.1 Symptoms of MALT lymphoma. Cancer research UK 2016. http://www.cancerresearchuk.org/about-cancer/type/non-hodgkins-lymphoma/about/types/mucosaassociated-lymphoid-tissue-lymphoma. Accessed on January 28, 2016
- ↑ Signs and symptoms of gastric lymphoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Gastric_lymphoma. Accessed on January 28, 2016
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Non-gastric lymphomas – causes, symptoms and treatments. Lymphoma association 2016. https://www.lymphomas.org.uk/sites/default/files/pdfs/Non-Gastric-malt-lymphoma.pdf. Accessed on January 28, 2016
- ↑ Clinical presentation of orbital lymphoma. Dr Craig Hacking and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/orbital-lymphoma. Accessed on January 28, 2016