Lymphangitis medical therapy

Lymphangitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]

Overview

Lymphangitis most often is an acute complication following an extension from the skin infection with the potential of a systemic spread. It has to be promptly treated with appropriate antibiotics along with analgesics, anti-inflammatory medications, warm and moist compresses. Certain conditions like nodular lymphagitis that is complicated by abscess and lymphedema with significant lymphatic obstruction may require surgical intervention.

Therapy Based on Clinical Form

Acute Lymphangitis

Empiric Therapy

▸ Click on the following categories to expand treatment regimens.

Acute Lymphangitis   ▸  Mild - Moderate   ▸  Severe

Mild - Moderate Preferred Regimen ▸ Penicillin V 500 mg PO q6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 300-450 mg PO q8h OR ▸Vancomycin 15-20 mg/kg IV q8-12h For Suspected MSSA ▸ Dicloxacillin 500 mg PO q6h OR ▸Cephalexin 500 mg PO q6h OR ▸Clindamycin 300-450 mg PO q8h OR ▸ Erythromycin 500 mg PO q6h For Suspected MRSA ▸ Vancomycin 15-20 mg/kg IV q8-12h OR ▸Linezolid 600 mg IV/PO q12h OR ▸Daptomycin 4mg/kg IV q24h OR ▸Clindamycin 600 mg IV/PO q8h OR ▸Doxycycline 100 mg PO q12h OR ▸Minocycline 100 mg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h Severe Preferred Regimen ▸ Penicillin G 2-4 MU IV q4-6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 300-450 mg PO q8h OR ▸Vancomycin 15-20 mg/kg IV q8-12h For Suspected MSSA ▸ Dicloxacillin 500 mg PO q6h OR ▸Cephalexin 500 mg PO q6h OR ▸Clindamycin 300-450 mg PO q8h OR ▸ Erythromycin 500 mg PO q6h For Suspected MRSA ▸ Vancomycin 15-20 mg/kg IV q8-12h OR ▸Linezolid 600 mg IV/PO q12h OR ▸Daptomycin 4mg/kg IV q24h OR ▸Clindamycin 600 mg IV/PO q8h OR ▸Doxycycline 100 mg PO q12h OR ▸Minocycline 100 mg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h

References