Lymphangitis medical therapy

Lymphangitis Microchapters
Home
Overview
Historical Perspective
Classification
Causes
Pathophysiology
Differentiating Lymphangitis from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
Case Studies
Case #1
Lymphangitis medical therapy On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Lymphangitis medical therapy All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Lymphangitis medical therapy
CDC on Lymphangitis medical therapy
Lymphangitis medical therapy in the news
Blogs on Lymphangitis medical therapy
Directions to Hospitals Treating Lymphangitis
Risk calculators and risk factors for Lymphangitis medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]

Overview

Lymphangitis most often is an acute complication following an extension from the skin infection with the potential of a systemic spread. It has to be promptly treated with appropriate antibiotics along with analgesics, anti-inflammatory medications, warm and moist compresses. Certain conditions like nodular lymphagitis that is complicated by abscess and lymphedema with significant lymphatic obstruction may require surgical intervention.

Therapy Based on Clinical Form

Acute Lymphangitis

Empiric Therapy

▸ Click on the following categories to expand treatment regimens.

Mild - Moderate Acute Lymphangitis   ▸  Adults   ▸   Children age >28 days Severe Acute Lymphangitis   ▸  Adults   ▸   Children age >28 days

Mild - Moderate Acute Lymphangitis - Adults Preferred Regimen ▸ Penicillin V 500 mg PO q6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 300-450 mg PO q8h OR ▸Vancomycin 15-20 mg/kg IV q8-12h For Suspected MSSA ▸ Dicloxacillin 500 mg PO q6h OR ▸Cephalexin 500 mg PO q6h OR ▸Clindamycin 300-450 mg PO q8h OR ▸ Erythromycin 500 mg PO q6h For Suspected MRSA ▸ Vancomycin 15-20 mg/kg IV q8-12h OR ▸Linezolid 600 mg IV/PO q12h OR ▸Daptomycin 4mg/kg IV q24h OR ▸Clindamycin 600 mg IV/PO q8h OR ▸Doxycycline 100 mg PO q12h OR ▸Minocycline 100 mg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h Mild - Moderate Acute Lymphangitis - Children Preferred Regimen ▸ Penicillin V 500 mg PO q6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 10-13 mg/kg IV q6-8h (max:40 mg/kg/day) OR ▸Vancomycin 15 mg/kg IV q6h For Suspected MSSA ▸ Dicloxacillin 25 mg/kg/day PO divided q6h OR ▸Cephalexin 25 mg/kg/day PO divided q6h OR ▸Clindamycin 10-13 mg/kg IV q6-8h (max:40 mg/kg/day) OR ▸ Erythromycin 10 mg/kg/dose PO q6h For Suspected MRSA ▸ Vancomycin 15 mg/kg IV q6h OR ▸Linezolid 10 mg/kg IV/PO q8h (max: 600mg/dose) OR ▸Daptomycin 5-9 mg/kg IV q24h OR ▸Clindamycin 10-13 mg/kg IV/PO q6-8h (max:40 mg/kg/day) OR ▸Doxycycline ≤45 kg: 2 mg/kg PO q12h; >45 kg: 100 mg PO q12h OR ▸Minocycline 2 mg/kg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h

Severe Acute Lymphangitis - Adults Preferred Regimen ▸ Penicillin G 2-4 MU IV q4-6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 300-450 mg PO q8h OR ▸Vancomycin 15-20 mg/kg IV q8-12h For Suspected MSSA ▸ Dicloxacillin 500 mg PO q6h OR ▸Cephalexin 500 mg PO q6h OR ▸Clindamycin 300-450 mg PO q8h OR ▸ Erythromycin 500 mg PO q6h For Suspected MRSA ▸ Vancomycin 15-20 mg/kg IV q8-12h OR ▸Linezolid 600 mg IV/PO q12h OR ▸Daptomycin 4mg/kg IV q24h OR ▸Clindamycin 600 mg IV/PO q8h OR ▸Doxycycline 100 mg PO q12h OR ▸Minocycline 100 mg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h

Severe Acute Lymphangitis - Children Preferred Regimen ▸ Penicillin G 2-4 MU IV q4-6h Alternative Regimen For Life-Threatening Penicillin Allergies ▸Clindamycin 10-13 mg/kg IV q6-8h (max:40 mg/kg/day) OR ▸Vancomycin 15 mg/kg IV q6h For Suspected MSSA ▸ Dicloxacillin 25 mg/kg/day PO divided q6h OR ▸Cephalexin 25 mg/kg/day PO divided q6h OR ▸Clindamycin 10-13 mg/kg IV q6-8h (max:40 mg/kg/day) OR ▸ Erythromycin 10 mg/kg/dose PO q6h For Suspected MRSA ▸ Vancomycin 15 mg/kg IV q6h OR ▸Linezolid 10 mg/kg IV/PO q8h (max: 600mg/dose) OR ▸Daptomycin 5-9 mg/kg IV q24h OR ▸Clindamycin 10-13 mg/kg IV/PO q6-8h (max:40 mg/kg/day) OR ▸Doxycycline ≤45 kg: 2 mg/kg PO q12h; >45 kg: 100 mg PO q12h OR ▸Minocycline 2 mg/kg PO q12h OR ▸TMP-SMX 8-12 mg/kg PO q12h/IV q6h

|}

Pathogen-Based Therapy

References