Lymphadenopathy natural history, complications and prognosis: Difference between revisions
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{{Lymphadenopathy}} | {{Lymphadenopathy}} | ||
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==Overview== | |||
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].Common complications of lymphadenopathy depends on the site of involvement, e.g. mediastinal lymphadenopathy include compression symptoms like[[Tracheal]] and bronchial obstruction and [[Dysphagia]] in [[Superior vena cava syndrome]]. Prognosis is generally excellent for infectious causes. Prompt treatment with antibiotics usually leads to a complete recovery. However, it may take weeks, or even months, for swelling to disappear. The amount of time to recovery depends on the cause. Prognosis is poor for [[malignant]] tumors. | |||
==Natural History== | ==Natural History== | ||
The natural course of lymphadenopathy depends on the underlying cause. Lymphadenopathy due to infectious causes subsides once the infection is controlled. | The natural course of lymphadenopathy depends on the underlying cause. Lymphadenopathy due to infectious causes subsides once the infection is controlled. | ||
== Natural History, Complications and Prognosis== | == Natural History, Complications and Prognosis== | ||
*Patients with lymphadenopathy may be symptomatic or asymptomatic, depending on the aetiology.<ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |year=2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref> | *Patients with lymphadenopathy may be symptomatic or asymptomatic, depending on the aetiology.<ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |year=2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref> | ||
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* [[Fistulas]] (seen in lymphadenitis that is due to [[tuberculosis]]) | * [[Fistulas]] (seen in lymphadenitis that is due to [[tuberculosis]]) | ||
* [[Sepsis]] | * [[Sepsis]] | ||
Revision as of 21:53, 18 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].Common complications of lymphadenopathy depends on the site of involvement, e.g. mediastinal lymphadenopathy include compression symptoms likeTracheal and bronchial obstruction and Dysphagia in Superior vena cava syndrome. Prognosis is generally excellent for infectious causes. Prompt treatment with antibiotics usually leads to a complete recovery. However, it may take weeks, or even months, for swelling to disappear. The amount of time to recovery depends on the cause. Prognosis is poor for malignant tumors.
Natural History
The natural course of lymphadenopathy depends on the underlying cause. Lymphadenopathy due to infectious causes subsides once the infection is controlled.
Natural History, Complications and Prognosis
- Patients with lymphadenopathy may be symptomatic or asymptomatic, depending on the aetiology.[1]
- Early clinical features include palpable tenderness, pain, and fever.
- Common complications of lymphadenopathy, include:
Mediastinal lymphadenopathy
- Superior vena cava syndrome
- Tracheal and bronchial obstruction
- Dysphagia
- Hemoptysis
- Uric acid nephropathy
- Hyperkalemia
- Hypercalcemia
- Hypocalcemia
- Hyperphosphatemia
- Renal failure
Abdominal lymphadenopathy
Superficial lymphadenopathy
- Abscess formation
- Cellulitis
- Fistulas (seen in lymphadenitis that is due to tuberculosis)
- Sepsis
Complications
- Mediastinal lymphadenopathy causes pressure symptoms like:
- Superior vena cava syndrome
- Tracheal and bronchial obstruction
- Dysphagia
- Hemoptysis
- Uric acid nephropathy
- Hyperkalemia
- Hypercalcemia
- Hypocalcemia
- Hyperphosphatemia
- Renal failure
- Abdominal lymphadenopathy can cause
- Superficial lymphadenopathy can cause
- Abscess formation
- Cellulitis (a skin infection)
- Fistulas (seen in lymphadenitis that is due to tuberculosis)
- Sepsis (bloodstream infection)
Prognosis
Prompt treatment with antibiotics usually leads to a complete recovery. However, it may take weeks, or even months, for swelling to disappear. The amount of time to recovery depends on the cause. Prognosis is poor for malignant tumors.