Lupus nephritis epidemiology and demographics: Difference between revisions

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__NOTOC__
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{{Lupus nephritis}}
{{Lupus nephritis}}
{{CMG}}
{{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User:Okamal|Omer Kamal, M.D.]][Mailto:okamal@bidmc.harvard.edu| <nowiki>[2]</nowiki>]


==Overview==
==Overview==
The incidence of lupus nephritis is 34 to 51 percent in Blacks, 31 to 43 percent in Hispanics, 33 to 55 percent in Asians, and 14 to 23 percent in Whites. In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women).The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.Chronic disease name is usually first diagnosed among middle age patients. African Americans have a higher frequency of developing Lupus nephritis in the United States.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The incidence of lupus nephritis is different among:<ref name="pmid23203603">{{cite journal |vauthors=Feldman CH, Hiraki LT, Liu J, Fischer MA, Solomon DH, Alarcón GS, Winkelmayer WC, Costenbader KH |title=Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004 |journal=Arthritis Rheum. |volume=65 |issue=3 |pages=753–63 |date=March 2013 |pmid=23203603 |pmc=3733212 |doi=10.1002/art.37795 |url=}}</ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
<blockquote>Blacks: 34 to 51 percent</blockquote><blockquote>Hispanics: 31 to 43 percent</blockquote><blockquote>Asians: 33 to 55 percent </blockquote><blockquote>Whites: 14 to 23 percent</blockquote>
* In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women)<ref name="pmid23203603" />


===Prevalence===
===Prevalence===
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|4.8 to 78.5
|4.8 to 78.5
|-
|-
|Europe<ref name="pmidPMID: 167615083">{{cite journal| author=Danchenko N, Satia JA, Anthony MS| title=Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. | journal=Lupus | year= 2006 | volume= 15 | issue= 5 | pages= 308-18 | pmid=PMID: 16761508 | doi=10.1191/0961203306lu2305xx | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16761508  }}</ref>
|Europe<ref name="pmidPMID: 16761508" />
|25 to 91
|25 to 91
|-
|-
|Australia<ref name="pmidPMID: 167615084">{{cite journal| author=Danchenko N, Satia JA, Anthony MS| title=Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. | journal=Lupus | year= 2006 | volume= 15 | issue= 5 | pages= 308-18 | pmid=PMID: 16761508 | doi=10.1191/0961203306lu2305xx | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16761508  }}</ref>
|Australia<ref name="pmidPMID: 16761508" />
|19 to 63
|19 to 63
|-
|-
|Japan<ref name="pmidPMID: 20947544">{{cite journal| author=Osio-Salido E, Manapat-Reyes H| title=Epidemiology of systemic lupus erythematosus in Asia. | journal=Lupus | year= 2010 | volume= 19 | issue= 12 | pages= 1365-73 | pmid=PMID: 20947544 | doi=10.1177/0961203310374305 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20947544  }}</ref>
|Japan<ref name="pmidPMID: 16761508" />
|8 to 18
|8 to 18
|-
|-
|China<ref name="pmidPMID: 209475442">{{cite journal| author=Osio-Salido E, Manapat-Reyes H| title=Epidemiology of systemic lupus erythematosus in Asia. | journal=Lupus | year= 2010 | volume= 19 | issue= 12 | pages= 1365-73 | pmid=PMID: 20947544 | doi=10.1177/0961203310374305 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20947544  }}</ref>
|China<ref name="pmidPMID: 16761508" />
|30 to 50
|30 to 50
|}
|}


===Case-fatality rate/Mortality rate===
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The overall [[mortality rate]] of lupus is very high, estimated to have approximately 50,000 deaths per 100,000 cases.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].


===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Patients of all age groups may develop Lupus nephritis.<ref name="pmidPMID: 16761508" />
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.<ref name="pmidPMID: 16761508" />
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*Lupus nephritis commonly affects individuals older than 18 years of age.  
*[Chronic disease name] is usually first diagnosed among [age group].
*Chronic disease name is usually first diagnosed among middle age patients.<ref name="pmidPMID: 16761508" />
*[Acute disease name] commonly affects [age group].
*Acute disease commonly affects young females.


===Race===
===Race===
*There is no racial predilection to [disease name].
* In 1995, the incidence of [[SLE]] was estimated to be 2.0 in White adults, 0.4 in White men, 3.5 in White women, 5.3 in African American adults, and 0.7 African America men.<ref name="pmid23203603" />
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].


===Gender===
===Gender===
Females are more commonly affected with Lupus nephritis. With an overall female to male ratio of approximately 8:1 in adults and 4:3 in children.<ref name="pmid278213903">{{cite journal| author=Almaani S, Meara A, Rovin BH| title=Update on Lupus Nephritis. | journal=Clin J Am Soc Nephrol | year= 2017 | volume= 12 | issue= 5 | pages= 825-835 | pmid=27821390 | doi=10.2215/CJN.05780616 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27821390  }}</ref>  
*Females are more commonly affected with Lupus nephritis. With an overall female to male ratio of approximately 8:1 in adults and 4:3 in children.<ref name="pmidPMID: 16761508" />


===Race===
===Race===
African Americans have a higher frequency of developing Lupus nephritis in the United States.<ref name="pmid278213904">{{cite journal| author=Almaani S, Meara A, Rovin BH| title=Update on Lupus Nephritis. | journal=Clin J Am Soc Nephrol | year= 2017 | volume= 12 | issue= 5 | pages= 825-835 | pmid=27821390 | doi=10.2215/CJN.05780616 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27821390  }}</ref>
*African Americans have a higher frequency of developing Lupus nephritis in the United States.<ref name="pmidPMID: 16761508" />
{| class="wikitable"
{| class="wikitable"
! colspan="2" |Frequency rate %<ref name="pmid278213905">{{cite journal| author=Almaani S, Meara A, Rovin BH| title=Update on Lupus Nephritis. | journal=Clin J Am Soc Nephrol | year= 2017 | volume= 12 | issue= 5 | pages= 825-835 | pmid=27821390 | doi=10.2215/CJN.05780616 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27821390  }}</ref>
! colspan="2" |Frequency rate %<ref name="pmid27821390" />
|-
|-
|Caucasian
|Caucasian
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|}
|}


===Developing Countries===
==References==
===Developed Countries===
{{Reflist|2}}


==References==
{{reflist|2}}
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Nephrology]]
[[Category:Nephrology]]
[[Category:Autoimmune diseases]]
[[Category:Autoimmune diseases]]
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Latest revision as of 12:19, 25 July 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]

Overview

The incidence of lupus nephritis is 34 to 51 percent in Blacks, 31 to 43 percent in Hispanics, 33 to 55 percent in Asians, and 14 to 23 percent in Whites. In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women).The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.Chronic disease name is usually first diagnosed among middle age patients. African Americans have a higher frequency of developing Lupus nephritis in the United States.

Epidemiology and Demographics

Incidence

  • The incidence of lupus nephritis is different among:[1]

Blacks: 34 to 51 percent

Hispanics: 31 to 43 percent

Asians: 33 to 55 percent

Whites: 14 to 23 percent

  • In 2005, Incidence was fiund to be 5.1 (Overall), 1.9 (Adult men), 8.2 (Adult women)[1]

Prevalence

Systemic Lupus Erythematosus (per 100,000)[2]
North America[3] 4.8 to 78.5
Europe[3] 25 to 91
Australia[3] 19 to 63
Japan[3] 8 to 18
China[3] 30 to 50

Case-fatality rate/Mortality rate

  • The overall mortality rate of lupus is very high, estimated to have approximately 50,000 deaths per 100,000 cases.

Age

  • Patients of all age groups may develop Lupus nephritis.[3]
  • The incidence of Lupus nephritis increases with age upto 50 years; the median age at diagnosis is 25 years.[3]
  • Lupus nephritis commonly affects individuals older than 18 years of age.
  • Chronic disease name is usually first diagnosed among middle age patients.[3]
  • Acute disease commonly affects young females.

Race

  • In 1995, the incidence of SLE was estimated to be 2.0 in White adults, 0.4 in White men, 3.5 in White women, 5.3 in African American adults, and 0.7 African America men.[1]

Gender

  • Females are more commonly affected with Lupus nephritis. With an overall female to male ratio of approximately 8:1 in adults and 4:3 in children.[3]

Race

  • African Americans have a higher frequency of developing Lupus nephritis in the United States.[3]
Frequency rate %[2]
Caucasian 29
Asian 40-82
Hispanic 61
Black 69

References

  1. 1.0 1.1 1.2 Feldman CH, Hiraki LT, Liu J, Fischer MA, Solomon DH, Alarcón GS, Winkelmayer WC, Costenbader KH (March 2013). "Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004". Arthritis Rheum. 65 (3): 753–63. doi:10.1002/art.37795. PMC 3733212. PMID 23203603.
  2. 2.0 2.1 Almaani S, Meara A, Rovin BH (2017). "Update on Lupus Nephritis". Clin J Am Soc Nephrol. 12 (5): 825–835. doi:10.2215/CJN.05780616. PMID 27821390.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Danchenko N, Satia JA, Anthony MS (2006). "Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden". Lupus. 15 (5): 308–18. doi:10.1191/0961203306lu2305xx. PMID 16761508 PMID: 16761508 Check |pmid= value (help).

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