Lisch nodule overview: Difference between revisions
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==Overview== | ==Overview== | ||
A '''Lisch nodule''' is a [[hamartoma]] (a type of benign [[tumor]]) affecting the [[Iris (anatomy)|iris]]. | A '''Lisch nodule''' is a [[hamartoma]] (a type of [[benign]] [[tumor]]) affecting the [[Iris (anatomy)|iris]]. These [[nodule]]s are typically found in [[neurofibromatosis type 1]]. They are clear [[yellow]] to brown, [[Domes|dome]]-shaped [[Elevation|elevations]] that project from the [[Surface area|surface]] of the [[Iris (anatomy)|iris]]. [[Lisch nodule|Lisch nodules]] are theorized to arise from [[mast cells]], [[Pigment cells|pigmented]] [[Cells (biology)|cells]] and [[fibroblast]]-like [[Cells (biology)|cells]]. In 80% of [[eyes]], [[Lisch nodules]] may be found in the inferior [[Quadrant|quadrants]] of the [[iris]] and this may be related to greater [[sun exposure]], one of the postulated factors in the [[development]] of these [[benign]] tumefactions. They can be detected by an [[optometrist]] or an [[ophthalmologist]] using a [[slit lamp]]. These [[nodules]] do not affect [[vision]]. They were named after Austrian [[ophthalmology|ophthalmologist]] Karl Lisch (1907-1999), who published an article about them in 1937. | ||
These [[nodule]]s are typically found in [[neurofibromatosis type 1]]. They are clear yellow to brown, dome-shaped elevations that project from the surface of the iris. They can be detected by an [[ | |||
They were named after Austrian [[ophthalmology|ophthalmologist]] Karl Lisch (1907-1999), who published an article about them in 1937. | |||
==References== | ==References== | ||
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[[Category:Ophthalmology]] | |||
Latest revision as of 13:41, 10 June 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Swathi Venkatesan, M.B.B.S.[2]
Overview
A Lisch nodule is a hamartoma (a type of benign tumor) affecting the iris. These nodules are typically found in neurofibromatosis type 1. They are clear yellow to brown, dome-shaped elevations that project from the surface of the iris. Lisch nodules are theorized to arise from mast cells, pigmented cells and fibroblast-like cells. In 80% of eyes, Lisch nodules may be found in the inferior quadrants of the iris and this may be related to greater sun exposure, one of the postulated factors in the development of these benign tumefactions. They can be detected by an optometrist or an ophthalmologist using a slit lamp. These nodules do not affect vision. They were named after Austrian ophthalmologist Karl Lisch (1907-1999), who published an article about them in 1937.