Linitis plastica epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

The exact incidence and prevalence for linitis plastica is unknown, however, linitis plastica is estimated to account for almost 30% of gastric cancers (previously thought to be 10%) with a declining incidence. There is a particularly high incidence rate in those individuals belonging to the Korean, Chinese and Japanese races.

Epidemiology and Demographics

Incidence

  • The exact incidence of linitis plastica is unknown.[1]
  • The incidence for gastric cancer overall in 2012 was 7.2 per 100,000 in the United States.
  • Linitis plastica was previously thought to account for 10% of gastric cancer, but now may account for as much as 30% of gastric cancers.
  • There has been a gradual decline in the incidence of linitis plastica.

Prevalence

Case-fatality rate/Mortality rate

The number of deaths is 3.2 per 100,000 men and women per year.[1]

Age

Linitis plastica commonly affects individuals younger than 40 years of age. The median age at diagnosis is between 20 - 25 years.[1]

Race

Linitis plastica usually affects individuals of Asian origin including Korean, Chinese, Taiwanese and Japanese populations. However, it is becoming more frequent in Europe.[1]

Race Number affected by gastric cancer per 100,000
Male Female
White 9 4.5
Black 13.6 7.8
Hispanic 13 8.5
Non-Hispanic 13.7 8.1
Asian/Pacific Islander 14 8
American Indian/Alaskan Native 13.7 8.1

Gender

Linitis plastica affects men and women equally.[1]

Region

The majority of linitis plastica cases are reported in Asia in countries including China and Japan.[2]


References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Siegel R, Ma J, Zou Z, Jemal A (2014). "Cancer statistics, 2014". CA Cancer J Clin. 64 (1): 9–29. doi:10.3322/caac.21208. PMID 24399786.
  2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011). "Global cancer statistics". CA Cancer J Clin. 61 (2): 69–90. doi:10.3322/caac.20107. PMID 21296855.



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