Hypercholesterolemia causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Hypercholesterolemia}}
{{Hypercholesterolemia}}
{{CMG}}
{{CMG}} {{AE}} {{LRO}}


==Overview==
==Overview==


==Causes==
==Causes==
===Common Causes===
*[[Abetalipoproteinemi ]]
*[[Alagille syndrome]]
*[[ApoA1 deficiency]]
*[[Apob mutation]]
*[[Apolipoprotein c-ii deficiency]]
*[[Apoprotein e deficiency]]
*[[Beckwith-wiedemann syndrome]]
*[[Beta blockers]]
*[[Carbohydrate intake]]
*[[Cholestatic jaundice]]
*[[Chronic renal insufficiency]]
*[[Ciclosporin]]
*[[Cushing’s syndrome]]
*[[Diabetes mellitus]]
*[[Diabetes mellitus type 2]]
*[[Dialysis]]
*[[Familial defective apolipoprotein b-100]]
*[[Familial mixed hyperlipidaemia]]
*[[Hypothyroidism]]
*[[Idiopathic]]
*[[Lack of exercise]]
*[[Lack of physical activity]]
*[[Ldl receptor deficiency]]
*[[Ldlr mutation]]
*[[Ldlrap1 mutation]]
*[[Lipoprotein lipase deficiency]]
*[[Malignant hepatopathy]]
*[[Metabolic syndrome]]
*[[Monoclonal gammopathy]]
*[[Nephrotic syndrome]]
*[[Obesity]]
*[[Obstructive liver disease]]
*[[Oculomotor apraxia syndrome ]]
*[[Pcsk9 mutation]]
*[[Tobacco ]]
*[[Trans fatty acids]]
*[[Vitamin e deficiency]]


===Dietary influence===
===Causes by Organ System===
While part of the circulating cholesterol originates from diet, and restricting cholesterol intake may reduce blood cholesterol levels, there are various other links between the dietary pattern and cholesterol levels. The American Heart Association also compiles a list of the acceptable/unacceptable foods for those who are diagnosed with hypercholesterolemia.
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Abetalipoproteinemia ]],  [[ApoA1 deficiency]],  [[Apob mutation]],  [[Apolipoprotein c-ii deficiency]],  [[Apoprotein e deficiency]],  [[Beta blockers]],  [[Cholesterol ester storage disease]],  [[Ldl receptor deficiency]],  [[Ldlr mutation]],  [[Ldlrap1 mutation]],  [[Lipoprotein lipase deficiency]]
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Alcohol]],  [[Retinoic acid]],  [[Tobacco ]]
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Ciclosporin]],  [[Fosamprenavir]],  [[Glucocorticoids]],  [[Medications]],  [[Mitotane]],  [[Siltuximab]],  [[Sirolimus]],  [[Temsirolimus]],  [[Thiazide diuretics]],  [[Tocilizumab]],  [[Tofacitinib]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| [[Cushing’s syndrome]],  [[Glycogenosis type 1a]],  [[Glycogenosis type 3]],  [[Glycogenosis type 6]],  [[Hypothyroidism]]
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Alagille syndrome]],  [[Analbuminaemia]],  [[Cholestatic jaundice]],  [[Glycogenosis type 1a]],  [[Glycogenosis type 3]],  [[Glycogenosis type 6]],  [[Malignant hepatopathy]],  [[Obstructive liver disease]],  [[Zieve's syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| [[Abetalipoproteinemia ]],  [[Alström syndrome]],  [[Beckwith-wiedemann syndrome]],  [[Chromosome 14 uniparental disomy syndrome ]],  [[Chromosome 3, trisomy 3p]],  [[Familial defective apolipoprotein b-100]],  [[Familial mixed hyperlipidaemia]],  [[Pcsk9 mutation]],  [[Werner syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| [[Analbuminaemia]],  [[ApoA1 deficiency]],  [[Apob mutation]],  [[Apolipoprotein c-ii deficiency]],  [[Apoprotein e deficiency]],  [[Beta blockers]],  [[Cholesterol ester storage disease]],  [[Familial defective apolipoprotein b-100]],  [[Familial mixed hyperlipidaemia]],  [[Ldl receptor deficiency]],  [[Ldlr mutation]],  [[Ldlrap1 mutation]],  [[Lipoprotein lipase deficiency]],  [[Monoclonal gammopathy]], [[Pcsk9 mutation]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Carbohydrate intake]],  [[Diabetes mellitus type 2]],  [[Diabetes mellitus]],  [[Lack of exercise]], [[Lack of physical activity]],  [[Metabolic syndrome]],  [[Obesity]],  [[Trans fatty acids]],  [[Vitamin e deficiency]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| [[Pregnancy]]
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Carcinoma]],  [[Cholestatic jaundice]]
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Oculomotor apraxia syndrome ]]
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Alcohol]], [[Zieve's syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| [[Anorexia nervosa]]
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Chronic renal insufficiency]],  [[Dialysis]],  [[Malignant hepatopathy]],  [[Nephrotic syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| [[Dialysis]]
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}


====Carbohydrates====
===Causes in Alphabetical Order===
Evidence is accumulating that eating more [[carbohydrate]]s - especially simpler, more refined carbohydrates - increases levels of [[triglycerides]] in the blood, lowers HDL, and may shift the LDL particle distribution pattern into unhealthy [[atheroma|atherogenic]] patterns. Thus a low fat diet, which often means a higher carbohydrate intake, may actually be an unhealthy change.
{{columns-list|3|
 
*[[Abetalipoproteinemia ]]
====Trans fats====
*[[Alagille syndrome]]
An increasing number of researchers are suggesting that a major dietary risk factor for cardiovascular diseases is [[trans fat|trans fatty acids]], and in the US the FDA has revised food labeling requirements to include listing trans fat quantities.
*[[Alcohol]]
*[[Alström syndrome]]
*[[Analbuminaemia]]
*[[Anorexia nervosa]]
*[[ApoA1 deficiency]]
*[[Apob mutation]]
*[[Apolipoprotein c-ii deficiency]]
*[[Apoprotein e deficiency]]
*[[Beckwith-wiedemann syndrome]]
*[[Beta blockers]]
*[[Carbohydrate intake]]
*[[Carcinoma]]
*[[Cholestatic jaundice]]
*[[Cholesterol ester storage disease]]
*[[Chromosome 14 uniparental disomy syndrome ]]
*[[Chromosome 3, trisomy 3p]]
*[[Chronic renal insufficiency]]
*[[Ciclosporin]]
*[[Cushing’s syndrome]]
*[[Cushing's syndrome]]
*[[Diabetes mellitus]]
*[[Diabetes mellitus type 2]]
*[[Dialysis]]
*[[Familial]]
*[[Familial defective apolipoprotein b-100]]
*[[Familial mixed hyperlipidaemia]]
*[[Fosamprenavir]]
*[[Glucocorticoids]]
*[[Glycogenosis type 1a]]
*[[Glycogenosis type 3]]
*[[Glycogenosis type 6]]
*[[Hypothyroidism]]
*[[Idiopathic]]
*[[Lack of exercise]]
*[[Lack of physical activity]]
*[[Ldl receptor deficiency]]
*[[Ldlr mutation]]
*[[Ldlrap1 mutation]]
*[[Lipoprotein lipase deficiency]]
*[[Malignant hepatopathy]]
*[[Medications]]
*[[Metabolic syndrome]]
*[[Mitotane]]
*[[Monoclonal gammopathy]]
*[[Nephrotic syndrome]]
*[[Obesity]]
*[[Obstructive liver disease]]
*[[Oculomotor apraxia syndrome ]]
*[[Pcsk9 mutation]]
*[[Pregnancy]]
*[[Retinoic acid]]
*[[Siltuximab]]
*[[Sirolimus]]
*[[Temsirolimus]]
*[[Thiazide diuretics]]
*[[Tobacco ]]
*[[Tocilizumab]]
*[[Tofacitinib]]
*[[Trans fatty acids]]
*[[Vitamin e deficiency]]
*[[Werner syndrome]]
*[[Zieve's syndrome]]
}}


==References==
==References==
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{{WS}}
{{WS}}


[[Category:Needs content]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Endocrinology]]
[[Category:Endocrinology]]

Revision as of 17:47, 15 November 2016

Template:Hypercholesterolemia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Causes

Common Causes

Causes by Organ System

Cardiovascular Abetalipoproteinemia , ApoA1 deficiency, Apob mutation, Apolipoprotein c-ii deficiency, Apoprotein e deficiency, Beta blockers, Cholesterol ester storage disease, Ldl receptor deficiency, Ldlr mutation, Ldlrap1 mutation, Lipoprotein lipase deficiency
Chemical/Poisoning Alcohol, Retinoic acid, Tobacco
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Ciclosporin, Fosamprenavir, Glucocorticoids, Medications, Mitotane, Siltuximab, Sirolimus, Temsirolimus, Thiazide diuretics, Tocilizumab, Tofacitinib
Ear Nose Throat No underlying causes
Endocrine Cushing’s syndrome, Glycogenosis type 1a, Glycogenosis type 3, Glycogenosis type 6, Hypothyroidism
Environmental No underlying causes
Gastroenterologic Alagille syndrome, Analbuminaemia, Cholestatic jaundice, Glycogenosis type 1a, Glycogenosis type 3, Glycogenosis type 6, Malignant hepatopathy, Obstructive liver disease, Zieve's syndrome
Genetic Abetalipoproteinemia , Alström syndrome, Beckwith-wiedemann syndrome, Chromosome 14 uniparental disomy syndrome , Chromosome 3, trisomy 3p, Familial defective apolipoprotein b-100, Familial mixed hyperlipidaemia, Pcsk9 mutation, Werner syndrome
Hematologic Analbuminaemia, ApoA1 deficiency, Apob mutation, Apolipoprotein c-ii deficiency, Apoprotein e deficiency, Beta blockers, Cholesterol ester storage disease, Familial defective apolipoprotein b-100, Familial mixed hyperlipidaemia, Ldl receptor deficiency, Ldlr mutation, Ldlrap1 mutation, Lipoprotein lipase deficiency, Monoclonal gammopathy, Pcsk9 mutation
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic Carbohydrate intake, Diabetes mellitus type 2, Diabetes mellitus, Lack of exercise, Lack of physical activity, Metabolic syndrome, Obesity, Trans fatty acids, Vitamin e deficiency
Obstetric/Gynecologic Pregnancy
Oncologic Carcinoma, Cholestatic jaundice
Ophthalmologic Oculomotor apraxia syndrome
Overdose/Toxicity Alcohol, Zieve's syndrome
Psychiatric Anorexia nervosa
Pulmonary No underlying causes
Renal/Electrolyte Chronic renal insufficiency, Dialysis, Malignant hepatopathy, Nephrotic syndrome
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma Dialysis
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

Template:WH Template:WS

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