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Revision as of 17:29, 13 November 2017

Gastroesophageal reflux disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Gastroesophageal Reflux Disease from other Diseases

Epidemiology and Demographics

Risk Factors

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Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

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Other Imaging Findings

Other Diagnostic Studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Esophagogastroduodenoscopy

Clinical practice guidelines from the American College of Physicians in 2012 recommend esophagogastroduodenoscopy if:[1]

  • Alarm symptoms
  • Persistence of symptoms after treatment
  • Barret's esophagus

However, espophagisitis may be found in asymptomatic patients.[2][3]

Other Diagnostic Studies

Other tests that may help include:

  • 48 hour esophageal pH and symptom association probability (SAP)[4]
  • Bernstein test (acid perfusion test).[5][6]

References

  1. Shaheen NJ, Weinberg DS, Denberg TD, Chou R, Qaseem A, Shekelle P; et al. (2012). "Upper endoscopy for gastroesophageal reflux disease: best practice advice from the clinical guidelines committee of the American College of Physicians". Ann Intern Med. 157 (11): 808–16. doi:10.7326/0003-4819-157-11-201212040-00008. PMID 23208168.
  2. Williams B, Luckas M, Ellingham JH, Dain A, Wicks AC (1988). "Do young patients with dyspepsia need investigation?". Lancet. 2 (8624): 1349–51. PMID 2904061.
  3. Johnsen R, Bernersen B, Straume B, Førde OH, Bostad L, Burhol PG (1991). "Prevalences of endoscopic and histological findings in subjects with and without dyspepsia". BMJ. 302 (6779): 749–52. PMC 1669538. PMID 2021764.
  4. Dent J, Vakil N, Jones R, Bytzer P, Schöning U, Halling K; et al. (2010). "Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study". Gut. 59 (6): 714–21. doi:10.1136/gut.2009.200063. PMID 20551454.
  5. Howard PJ, Maher L, Pryde A, Heading RC (1991). "Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease". Gut. 32 (2): 128–32. PMC 1378792. PMID 1864528.
  6. Hewson EG, Dalton CB, Richter JE (1990). "Comparison of esophageal manometry, provocative testing, and ambulatory monitoring in patients with unexplained chest pain". Dig Dis Sci. 35 (3): 302–9. PMID 2307075.

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