Gallbladder cancer laboratory tests: Difference between revisions

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{{Gallbladder cancer}}
{{Gallbladder cancer}}
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==Overview==
==Overview==
It is hard to detect early forms of gallbladder cancer. Like other cancer diseases, doctors need to administer many tests to diagnose cancer and determine whether it has metastasized. For most types of cancer, a [[biopsy]] is the best way to make a definitive diagnosis of cancer. If a biopsy is not possible, other image tests are recommended such as computed tomography (CT) scan, Magnetic resonance imaging (MRI) or Positron emission tomography (PET) scan.
There are some [[diagnostic]] laboratory findings associated with [[gallbladder cancer]], such as [[alkaline phosphatase]], serum [[bilirubin]], carcinoembryonic antigen ([[CEA]]), [[CA 19-9]].


==Blood Tests==
==Laboratory tests==
*Blood tests: Blood tests that look at levels of different kinds of bilirubin are also useful to decide whether a patient's jaundice is due to a disease of the liver or to blockage of bile flow.
There are no diagnostic laboratory findings associated with [[gallbladder carcinoma]].<ref name="pmid2335386">{{cite journal |vauthors=Strom BL, Maislin G, West SL, Atkinson B, Herlyn M, Saul S, Rodriguez-Martinez HA, Rios-Dalenz J, Iliopoulos D, Soloway RD |title=Serum CEA and CA 19-9: potential future diagnostic or screening tests for gallbladder cancer? |journal=Int. J. Cancer |volume=45 |issue=5 |pages=821–4 |year=1990 |pmid=2335386 |doi= |url=}}</ref><ref name="pmid21573879">{{cite journal |vauthors=Rana S, Dutta U, Kochhar R, Rana SV, Gupta R, Pal R, Jain K, Srinivasan R, Nagi B, Nain CK, Singh K |title=Evaluation of CA 242 as a tumor marker in gallbladder cancer |journal=J Gastrointest Cancer |volume=43 |issue=2 |pages=267–71 |year=2012 |pmid=21573879 |doi=10.1007/s12029-011-9288-7 |url=}}</ref>
 
Laboratory findings consistent with the diagnosis of [[gallbladder carcinoma]] include:
* An elevated [[alkaline phosphatase]] or serum [[bilirubin]] can be associated with [[bile duct]] [[obstruction]].
*<nowiki/><nowiki/><nowiki/>Serum [[tumor marker]]<nowiki/>s including [[carcinoembryonic antigen]] ([[CEA]]) or [[carbohydrate]] [[antigen]] 19-9 are frequently elevated, but they have lack of [[specificity]] and [[sensitivity]].
*<nowiki/> <nowiki/>CA 242 is a tumor <nowiki/>marker for [[gallbladder cancer]] and performs better than [[CEA]] and [[CA 19-9]].<ref name="pmid24744600">{{cite journal |vauthors=Wang YF, Feng FL, Zhao XH, Ye ZX, Zeng HP, Li Z, Jiang XQ, Peng ZH |title=Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer |journal=World J. Gastroenterol. |volume=20 |issue=14 |pages=4085–92 |date=April 2014 |pmid=24744600 |pmc=3983467 |doi=10.3748/wjg.v20.i14.4085 |url=}}</ref><ref name="pmid26421012">{{cite journal |vauthors=Kanthan R, Senger JL, Ahmed S, Kanthan SC |title=Gallbladder Cancer in the 21st Century |journal=J Oncol |volume=2015 |issue= |pages=967472 |date=2015 |pmid=26421012 |doi=10.1155/2015/967472 |url=}}</ref>
*<nowiki/>However, if a tumo<nowiki/>r marker is observed to be elevated preoperatively, serial assay after [[resection]] may useful resource within the analysis of chronic or recurrent disease.


==References==
==References==
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Oncology]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]



Latest revision as of 00:13, 13 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

There are some diagnostic laboratory findings associated with gallbladder cancer, such as alkaline phosphatase, serum bilirubin, carcinoembryonic antigen (CEA), CA 19-9.

Laboratory tests

There are no diagnostic laboratory findings associated with gallbladder carcinoma.[1][2]

Laboratory findings consistent with the diagnosis of gallbladder carcinoma include:

References

  1. Strom BL, Maislin G, West SL, Atkinson B, Herlyn M, Saul S, Rodriguez-Martinez HA, Rios-Dalenz J, Iliopoulos D, Soloway RD (1990). "Serum CEA and CA 19-9: potential future diagnostic or screening tests for gallbladder cancer?". Int. J. Cancer. 45 (5): 821–4. PMID 2335386.
  2. Rana S, Dutta U, Kochhar R, Rana SV, Gupta R, Pal R, Jain K, Srinivasan R, Nagi B, Nain CK, Singh K (2012). "Evaluation of CA 242 as a tumor marker in gallbladder cancer". J Gastrointest Cancer. 43 (2): 267–71. doi:10.1007/s12029-011-9288-7. PMID 21573879.
  3. Wang YF, Feng FL, Zhao XH, Ye ZX, Zeng HP, Li Z, Jiang XQ, Peng ZH (April 2014). "Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer". World J. Gastroenterol. 20 (14): 4085–92. doi:10.3748/wjg.v20.i14.4085. PMC 3983467. PMID 24744600.
  4. Kanthan R, Senger JL, Ahmed S, Kanthan SC (2015). "Gallbladder Cancer in the 21st Century". J Oncol. 2015: 967472. doi:10.1155/2015/967472. PMID 26421012.


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