Fibromuscular dysplasia physical examination: Difference between revisions

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{{Fibromuscular dysplasia}}
{{Fibromuscular dysplasia}}


{{CMG}}; {{AE}}
{{CMG}}; {{AE}}{{M.B}}


==Overview==
==Overview==
Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
Patients with FMD usually appear normal. In physical examination of patients with FMD mild to moderate [[hypertension]] may be detected. In the  auscultation of [[neck]] among patients with involvement of [[Common carotid artery|carotid artery]] or auscultation of [[epigastric]] or flank  of [[Renovascular disease|renovascular]] FMD bruits may be heard. Eventullay due to nonspecific sypmtoms and sings of FMD, the diagnosis of this disease needs highly clinical suspicion of healthcare provider.


==Physical Examination==
==Physical Examination==


*Physical examination of patients with fibromuscular dysplasia without clinical suspicion is usually normal. However the most common presentation of [[renal artery]] FMD is [[renovascular hypertension]], but in the physical examination of patients enrolled in the US registry for fibromuscular dysplasia mean blood pressure was 130/75 mm Hg.<ref>{{Cite journal
*Physical examination of patients with fibromuscular dysplasia is usually normal. However the most common presentation of [[renal artery]] FMD is [[renovascular hypertension]], but in the physical examination of patients enrolled in the US registry for fibromuscular dysplasia mean blood pressure was 130/75 mm Hg.<ref>{{Cite journal
  | author = [[Jeffrey W. Olin]], [[James Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Kim Eagle]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Esther S. H. Kim]], [[Pam Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Eva Kline-Rogers]], [[Christopher J. White]] & [[Heather L. Gornik]]
  | author = [[Jeffrey W. Olin]], [[James Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Kim Eagle]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Esther S. H. Kim]], [[Pam Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Eva Kline-Rogers]], [[Christopher J. White]] & [[Heather L. Gornik]]
  | title = The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients
  | title = The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients
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}}</ref>
}}</ref>


*The presence of [[carotid bruits]] on physical examination has low [[sensitivity]] however its [[specificity]] for identifying [[extracranial]] FMD is highly suggestive.  
*The presence of [[carotid bruits]] on physical examination has low [[sensitivity]] however its [[specificity]] for identifying extracranial FMD is highly suggestive.  
*The presence of an epigastric or [[Flanks|flank]] bruit on physical examination, such as  [[carotid bruits]] is low, however, its presence strongly suggestive of renal or mesenteric FMD.
*The presence of an epigastric or [[Flanks|flank]] bruit on physical examination, such as  [[carotid bruits]] is low, however, its presence strongly suggestive of [[Kidney|renal]] or [[Mesentery|mesenteric]] FMD.
*Focal neurological deficits,[[cranial nerve]] involvement, [[pupil]] abnormality or [[ptosis]] (findings consistent with [[Horner syndrome]]) may be detected in FMD.
*Focal neurological deficits, [[cranial nerve]] involvement, [[pupil]] abnormality or [[ptosis]] (findings consistent with [[Horner syndrome]]) may be detected in FMD.
 
Physical examination of patients with [disease name] is usually normal.
 
OR
 
Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
 
OR
 
The presence of [finding(s)] on physical examination is diagnostic of [disease name].
 
OR
 
The presence of [finding(s)] on physical examination is highly suggestive of [disease name].
===Appearance of the Patient===
===Appearance of the Patient===
*Patients with [disease name] usually appear [general appearance].
*Patients with FMD usually appear normal.
===Vital Signs===
===Vital Signs===
*High-grade / low-grade fever
*High blood pressure may be seen among patients with renovascular FMD.
*[[Hypothermia]] / hyperthermia may be present
*[[Tachycardia]] with regular pulse or (ir)regularly irregular pulse
*[[Bradycardia]] with regular pulse or (ir)regularly irregular pulse
*Tachypnea / bradypnea
*Kussmal respirations may be present in _____ (advanced disease state)
*Weak/bounding pulse / pulsus alternans / paradoxical pulse / asymmetric pulse
*High/low blood pressure with normal pulse pressure / [[wide pulse pressure]] / [[narrow pulse pressure]]
===Skin===
===Skin===
*Skin examination of patients with [disease name] is usually normal.
*Skin examination of patients with FMD is normal.
OR
*[[Cyanosis]]
*[[Jaundice]]
*[[Pallor]]
*Bruises<gallery widths="150px">


UploadedImage-01.jpg | Description {{dermref}}
UploadedImage-02.jpg | Description {{dermref}}
</gallery>
===HEENT===
===HEENT===
*HEENT examination of patients with [disease name] is usually normal.
*HEENT examination of patients with FMD is normal.  
OR
*Abnormalities of the head/hair may include ___
*Evidence of trauma
*Icteric sclera
*[[Nystagmus]]
*Extra-ocular movements may be abnormal
*Pupils non-reactive to light / non-reactive to accommodation / non-reactive to neither light nor accommodation
*Ophthalmoscopic exam may be abnormal with findings of ___
*Hearing acuity may be reduced
*[[Weber test]] may be abnormal (Note: A positive Weber test is considered a normal finding / A negative Weber test is considered an abnormal finding. To avoid confusion, you may write "abnormal Weber test".)
*[[Rinne test]] may be positive (Note: A positive Rinne test is considered a normal finding / A negative Rinne test is considered an abnormal finding. To avoid confusion, you may write "abnormal Rinne test".)
*[[Exudate]] from the ear canal
*Tenderness upon palpation of the ear pinnae/tragus (anterior to ear canal)
*Inflamed nares / congested nares
*[[Purulent]] exudate from the nares
*Facial tenderness
*Erythematous throat with/without tonsillar swelling, exudates, and/or petechiae
===Neck===
===Neck===
*Neck examination of patients with [disease name] is usually normal.
*[[Carotid bruits]] may be auscultated unilaterally or bilaterally using the bell of the stethoscope.
OR
*[[Jugular venous distension]]
*[[Carotid bruits]] may be auscultated unilaterally/bilaterally using the bell/diaphragm of the otoscope
*[[Lymphadenopathy]] (describe location, size, tenderness, mobility, and symmetry)
*[[Thyromegaly]] / thyroid nodules
*[[Hepatojugular reflux]]
===Lungs===
*Pulmonary examination of patients with [disease name] is usually normal.
OR
*Asymmetric chest expansion OR decreased chest expansion
*Lungs are hyporesonant OR hyperresonant
*Fine/coarse [[crackles]] upon auscultation of the lung bases/apices unilaterally/bilaterally
*Rhonchi
*Vesicular breath sounds OR distant breath sounds
*Expiratory wheezing OR inspiratory wheezing with normal OR delayed expiratory phase
*[[Wheezing]] may be present
*[[Egophony]] present/absent
*[[Bronchophony]] present/absent
*Normal/reduced [[tactile fremitus]]
===Heart===
*Cardiovascular examination of patients with [disease name] is usually normal.
OR
*Chest tenderness upon palpation
*PMI within 2 cm of the sternum  (PMI) / Displaced point of maximal impulse (PMI) suggestive of ____
*[[Heave]] / [[thrill]]
*[[Friction rub]]
*[[Heart sounds#First heart tone S1, the "lub"(components M1 and T1)|S1]]
*[[Heart sounds#Second heart tone S2 the "dub"(components A2 and P2)|S2]]
*[[Heart sounds#Third heart sound S3|S3]]
*[[Heart sounds#Fourth heart sound S4|S4]]
*[[Heart sounds#Summation Gallop|Gallops]]
*A high/low grade early/late [[systolic murmur]] / [[diastolic murmur]] best heard at the base/apex/(specific valve region) may be heard using the bell/diaphgram of the otoscope
===Abdomen===
===Abdomen===
*Abdominal examination of patients with [disease name] is usually normal.
*In abdominal examination of patients with FMD, epigastric or flank bruits may be heard.  
OR
 
*[[Abdominal distention]]
*[[Abdominal tenderness]] in the right/left upper/lower abdominal quadrant
*[[Rebound tenderness]] (positive Blumberg sign)
*A palpable abdominal mass in the right/left upper/lower abdominal quadrant
*Guarding may be present
*[[Hepatomegaly]] / [[splenomegaly]] / [[hepatosplenomegaly]]
*Additional findings, such as obturator test, psoas test, McBurney point test, Murphy test
===Back===
*Back examination of patients with [disease name] is usually normal.
OR
*Point tenderness over __ vertebrae (e.g. L3-L4)
*Sacral edema
*Costovertebral angle tenderness bilaterally/unilaterally
*Buffalo hump
===Genitourinary===
*Genitourinary examination of patients with [disease name] is usually normal.
OR
*A pelvic/adnexal mass may be palpated
*Inflamed mucosa
*Clear/(color), foul-smelling/odorless penile/vaginal discharge
===Neuromuscular===
*Neuromuscular examination of patients with [disease name] is usually normal.
OR
*Patient is usually oriented to persons, place, and time
*Altered mental status
*Glasgow coma scale is ___ / 15
*Clonus may be present
*Hyperreflexia / hyporeflexia / areflexia
*Positive (abnormal) Babinski / plantar reflex unilaterally/bilaterally
*Muscle rigidity
*Proximal/distal muscle weakness unilaterally/bilaterally
*____ (finding) suggestive of cranial nerve ___ (roman numerical) deficit (e.g. Dilated pupils suggestive of CN III deficit)
*Unilateral/bilateral upper/lower extremity weakness
*Unilateral/bilateral sensory loss in the upper/lower extremity
*Positive straight leg raise test
*Abnormal gait (describe gait: e.g. ataxic (cerebellar) gait / steppage gait / waddling gait / choeiform gait / Parkinsonian gait / sensory gait)
*Positive/negative Trendelenburg sign
*Unilateral/bilateral tremor (describe tremor, e.g. at rest, pill-rolling)
*Normal finger-to-nose test / Dysmetria
*Absent/present dysdiadochokinesia (palm tapping test)
===Extremities===
===Extremities===
*Extremities examination of patients with [disease name] is usually normal.
*While FMD involving the lower extremities most commonly involves the external [[iliac]] arteries, extremities examination of patients with FMD is usually normal, however, a bruit caused by [[iliac]] FMD may be heard in the lower abdomen from the [[umbilicus]] to the [[Inguinal region|inguinal]] region.
OR
*FMD involving the upper extremities most commonly involves the [[Brachial artery|brachial]] arteries, in some cases, there may be discrepant blood pressures in the  arms. Arm [[claudication]] or a [[bruit]] heard over the antecubital fossa is uncommon but may occur.<ref>{{Cite journal
*[[Clubbing]]
| author = [[Jeffrey W. Olin]], [[Heather L. Gornik]], [[J. Michael Bacharach]], [[Jose Biller]], [[Lawrence J. Fine]], [[Bruce H. Gray]], [[William A. Gray]], [[Rishi Gupta]], [[Naomi M. Hamburg]], [[Barry T. Katzen]], [[Robert A. Lookstein]], [[Alan B. Lumsden]], [[Jane W. Newburger]], [[Tatjana Rundek]], [[C. John Sperati]] & [[James C. Stanley]]
*[[Cyanosis]]
| title = Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association
*Pitting/non-pitting [[edema]] of the upper/lower extremities
| journal = [[Circulation]]
*Muscle atrophy
| volume = 129
*Fasciculations in the upper/lower extremity
| issue = 9
| pages = 1048–1078
| year = 2014
| month = March
| doi = 10.1161/01.cir.0000442577.96802.8c
| pmid = 24548843
}}</ref>


==References==
==References==

Latest revision as of 05:21, 6 May 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Overview

Patients with FMD usually appear normal. In physical examination of patients with FMD mild to moderate hypertension may be detected. In the auscultation of neck among patients with involvement of carotid artery or auscultation of epigastric or flank of renovascular FMD bruits may be heard. Eventullay due to nonspecific sypmtoms and sings of FMD, the diagnosis of this disease needs highly clinical suspicion of healthcare provider.

Physical Examination

  • Physical examination of patients with fibromuscular dysplasia is usually normal. However the most common presentation of renal artery FMD is renovascular hypertension, but in the physical examination of patients enrolled in the US registry for fibromuscular dysplasia mean blood pressure was 130/75 mm Hg.[1]

Appearance of the Patient

  • Patients with FMD usually appear normal.

Vital Signs

  • High blood pressure may be seen among patients with renovascular FMD.

Skin

  • Skin examination of patients with FMD is normal.

HEENT

  • HEENT examination of patients with FMD is normal.

Neck

  • Carotid bruits may be auscultated unilaterally or bilaterally using the bell of the stethoscope.

Abdomen

  • In abdominal examination of patients with FMD, epigastric or flank bruits may be heard.

Extremities

  • While FMD involving the lower extremities most commonly involves the external iliac arteries, extremities examination of patients with FMD is usually normal, however, a bruit caused by iliac FMD may be heard in the lower abdomen from the umbilicus to the inguinal region.
  • FMD involving the upper extremities most commonly involves the brachial arteries, in some cases, there may be discrepant blood pressures in the arms. Arm claudication or a bruit heard over the antecubital fossa is uncommon but may occur.[2]

References

  1. Jeffrey W. Olin, James Froehlich, Xiaokui Gu, J. Michael Bacharach, Kim Eagle, Bruce H. Gray, Michael R. Jaff, Esther S. H. Kim, Pam Mace, Alan H. Matsumoto, Robert D. McBane, Eva Kline-Rogers, Christopher J. White & Heather L. Gornik (2012). "The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients". Circulation. 125 (25): 3182–3190. doi:10.1161/CIRCULATIONAHA.112.091223. PMID 22615343. Unknown parameter |month= ignored (help)
  2. Jeffrey W. Olin, Heather L. Gornik, J. Michael Bacharach, Jose Biller, Lawrence J. Fine, Bruce H. Gray, William A. Gray, Rishi Gupta, Naomi M. Hamburg, Barry T. Katzen, Robert A. Lookstein, Alan B. Lumsden, Jane W. Newburger, Tatjana Rundek, C. John Sperati & James C. Stanley (2014). "Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association". Circulation. 129 (9): 1048–1078. doi:10.1161/01.cir.0000442577.96802.8c. PMID 24548843. Unknown parameter |month= ignored (help)

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