Fibromuscular dysplasia history and symptoms
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Management of Patients With Fibromuscular Dysplasia of the Extracranial Carotid Arteries |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.
Overview
Since Fibromuscular dysplasia can involve virtually every artery of the body, thus the clinical presentations of FMD vary widely and are determined by the vessels territories that are involved.The clinical presentations of FMD may result from the stenosis, occlusion, ischemia, dissection, rupture of aneurysms and embolization of intravascular thrombi from dissection or aneurysms.[1][2]
History and Symptoms
- The majority of patients with fibromuscular dysplasia are asymptomatic.
- The hallmark of FMD is hypertension in women with the prime of their life, whereas FMD can occur in both genders at any age, its presentations across the lifespan.
- In general, the clinical presentations of FMD in women as compared with men are somewhat different. Manifestations of cerebrovascular FMD are more likely to occur in women, whereas manifestations of renal FMD, arterial dissections and aneurysms are more common in men.[3]
History
Patients with fibromuscular dysplasia may have a positive history of:
Common Symptoms [4]
- The most common signs of FMD include hypertension, cervical bruit, abdominal bruit, and transient ischemic attack.
Less Common Symptoms
Less common symptoms of FMD include:
- Chest pain or shortness of breath
- Postprandial abdominal pain
- Claudication
- Amaurosis fugax
- Weight loss
- Horner syndrome
- Azotemia
- Myocardial infarction
- Mesenteric ischemia
References
- ↑ Jeffrey W. Olin & Brett A. Sealove (2011). "Diagnosis, management, and future developments of fibromuscular dysplasia". Journal of vascular surgery. 53 (3): 826–836. doi:10.1016/j.jvs.2010.10.066. PMID 021236620. Unknown parameter
|month=ignored (help) - ↑ Jeffrey W. Olin, Heather L. Gornik, J. Michael Bacharach, Jose Biller, Lawrence J. Fine, Bruce H. Gray, William A. Gray, Rishi Gupta, Naomi M. Hamburg, Barry T. Katzen, Robert A. Lookstein, Alan B. Lumsden, Jane W. Newburger, Tatjana Rundek, C. John Sperati & James C. Stanley (2014). "Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association". Circulation. 129 (9): 1048–1078. doi:10.1161/01.cir.0000442577.96802.8c. PMID 24548843. Unknown parameter
|month=ignored (help) - ↑ Esther S. H. Kim, Jeffrey W. Olin, James B. Froehlich, Xiaokui Gu, J. Michael Bacharach, Bruce H. Gray, Michael R. Jaff, Barry T. Katzen, Eva Kline-Rogers, Pamela D. Mace, Alan H. Matsumoto, Robert D. McBane, Christopher J. White & Heather L. Gornik (2013). "Clinical manifestations of fibromuscular dysplasia vary by patient sex: a report of the United States registry for fibromuscular dysplasia". Journal of the American College of Cardiology. 62 (21): 2026–2028. doi:10.1016/j.jacc.2013.07.038. PMID 23954333. Unknown parameter
|month=ignored (help) - ↑ Jeffrey W. Olin, James Froehlich, Xiaokui Gu, J. Michael Bacharach, Kim Eagle, Bruce H. Gray, Michael R. Jaff, Esther S. H. Kim, Pam Mace, Alan H. Matsumoto, Robert D. McBane, Eva Kline-Rogers, Christopher J. White & Heather L. Gornik (2012). "The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients". Circulation. 125 (25): 3182–3190. doi:10.1161/CIRCULATIONAHA.112.091223. PMID 22615343. Unknown parameter
|month=ignored (help)