Enolase 2: Difference between revisions

Jump to navigation Jump to search
m (Bot: HTTP→HTTPS)
 
imported>Citation bot
m (Alter: journal. Add: url, pmc. You can use this bot yourself. Report bugs here. | Headbomb)
 
Line 27: Line 27:
*{{cite journal  |vauthors=Pechumer H, Bender-Götze C, Ziegler-Heitbrock HW |title=Detection of neuron-specific gamma-enolase messenger ribonucleic acid in normal human leukocytes by polymerase chain reaction amplification with nested primers |journal=Lab. Invest. |volume=69 |issue= 6 |pages= 743–9 |year= 1994 |pmid= 8264236 |doi=  }}
*{{cite journal  |vauthors=Pechumer H, Bender-Götze C, Ziegler-Heitbrock HW |title=Detection of neuron-specific gamma-enolase messenger ribonucleic acid in normal human leukocytes by polymerase chain reaction amplification with nested primers |journal=Lab. Invest. |volume=69 |issue= 6 |pages= 743–9 |year= 1994 |pmid= 8264236 |doi=  }}
*{{cite journal  | author=Ansari-Lari MA |title=Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination |journal=Genome Res. |volume=7 |issue= 3 |pages= 268–80 |year= 1997 |pmid= 9074930 |doi=10.1101/gr.7.3.268  |name-list-format=vanc| author2=Shen Y  | author3=Muzny DM  | display-authors=3  | last4=Lee  | first4=W  | last5=Gibbs  | first5=R A  }}
*{{cite journal  | author=Ansari-Lari MA |title=Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination |journal=Genome Res. |volume=7 |issue= 3 |pages= 268–80 |year= 1997 |pmid= 9074930 |doi=10.1101/gr.7.3.268  |name-list-format=vanc| author2=Shen Y  | author3=Muzny DM  | display-authors=3  | last4=Lee  | first4=W  | last5=Gibbs  | first5=R A  }}
*{{cite journal  | author=Lau L |title=Neuroblastoma: a single institution's experience with 128 children and an evaluation of clinical and biological prognostic factors |journal=Pediatric hematology and oncology |volume=19 |issue= 2 |pages= 79–89 |year= 2002 |pmid= 11881792 |doi=10.1080/08880010252825669  }}
*{{cite journal  | author=Lau L |title=Neuroblastoma: a single institution's experience with 128 children and an evaluation of clinical and biological prognostic factors |journal=Pediatric Hematology and Oncology |volume=19 |issue= 2 |pages= 79–89 |year= 2002 |pmid= 11881792 |doi=10.1080/08880010252825669  }}
*{{cite journal  | author=Wijnberger LD |title=Expression in the placenta of neuronal markers for perinatal brain damage |journal=Pediatr. Res. |volume=51 |issue= 4 |pages= 492–6 |year= 2002 |pmid= 11919335 |doi=10.1203/00006450-200204000-00015  |name-list-format=vanc| author2=Nikkels PG  | author3=van Dongen AJ  | display-authors=3  | last4=Noorlander  | first4=Cornelle W.  | last5=Mulder  | first5=Eduard J.H.  | last6=Schrama  | first6=Loes H.  | last7=Visser  | first7=Gerard H.A.  }}
*{{cite journal  | author=Wijnberger LD |title=Expression in the placenta of neuronal markers for perinatal brain damage |journal=Pediatr. Res. |volume=51 |issue= 4 |pages= 492–6 |year= 2002 |pmid= 11919335 |doi=10.1203/00006450-200204000-00015  |name-list-format=vanc| author2=Nikkels PG  | author3=van Dongen AJ  | display-authors=3  | last4=Noorlander  | first4=Cornelle W.  | last5=Mulder  | first5=Eduard J.H.  | last6=Schrama  | first6=Loes H.  | last7=Visser  | first7=Gerard H.A.  }}
*{{cite journal  | author=O'Dwyer DT |title=Pituitary autoantibodies in lymphocytic hypophysitis target both gamma- and alpha-Enolase - a link with pregnancy? |journal=Arch. Physiol. Biochem. |volume=110 |issue= 1–2 |pages= 94–8 |year= 2002 |pmid= 11935405 |doi=10.1076/apab.110.1.94.897  |name-list-format=vanc| author2=Clifton V  | author3=Hall A  | display-authors=3  | last4=Smith  | first4=R.  | last5=Robinson  | first5=P.J.  | last6=Crock  | first6=P.A.  }}
*{{cite journal  | author=O'Dwyer DT |title=Pituitary autoantibodies in lymphocytic hypophysitis target both gamma- and alpha-Enolase - a link with pregnancy? |journal=Arch. Physiol. Biochem. |volume=110 |issue= 1–2 |pages= 94–8 |year= 2002 |pmid= 11935405 |doi=10.1076/apab.110.1.94.897  |name-list-format=vanc| author2=Clifton V  | author3=Hall A  | display-authors=3  | last4=Smith  | first4=R.  | last5=Robinson  | first5=P.J.  | last6=Crock  | first6=P.A.  }}
*{{cite journal  | author=Chekhonin VP |title=Serum time course of two brain-specific proteins, alpha(1) brain globulin and neuron-specific enolase, in tick-born encephalitis and Lyme disease |journal=Clin. Chim. Acta |volume=320 |issue= 1–2 |pages= 117–25 |year= 2002 |pmid= 11983209 |doi=10.1016/S0009-8981(02)00057-8  |name-list-format=vanc| author2=Zhirkov YA  | author3=Belyaeva IA  | display-authors=3  | last4=Ryabukhin  | first4=Igor A  | last5=Gurina  | first5=Olga I  | last6=Dmitriyeva  | first6=Tatiana B  }}
*{{cite journal  | author=Chekhonin VP |title=Serum time course of two brain-specific proteins, alpha(1) brain globulin and neuron-specific enolase, in tick-born encephalitis and Lyme disease |journal=Clin. Chim. Acta |volume=320 |issue= 1–2 |pages= 117–25 |year= 2002 |pmid= 11983209 |doi=10.1016/S0009-8981(02)00057-8  |name-list-format=vanc| author2=Zhirkov YA  | author3=Belyaeva IA  | display-authors=3  | last4=Ryabukhin  | first4=Igor A  | last5=Gurina  | first5=Olga I  | last6=Dmitriyeva  | first6=Tatiana B  }}
*{{cite journal  | author=Nakatsuka S |title=Enhanced expression of neuron-specific enolase (NSE) in pyothorax-associated lymphoma (PAL) |journal=Jpn. J. Cancer Res. |volume=93 |issue= 4 |pages= 411–6 |year= 2005 |pmid= 11985791 |doi= 10.1111/j.1349-7006.2002.tb01272.x |name-list-format=vanc| author2=Nishiu M  | author3=Tomita Y  | display-authors=3  | last4=Miwa  | first4=H  | last5=Takakuwa  | first5=T  | last6=Iuchi  | first6=K  | last7=Yamamoto  | first7=S  | last8=Aozasa  | first8=K  }}
*{{cite journal  | author=Nakatsuka S |title=Enhanced expression of neuron-specific enolase (NSE) in pyothorax-associated lymphoma (PAL) |journal=Jpn. J. Cancer Res. |volume=93 |issue= 4 |pages= 411–6 |year= 2005 |pmid= 11985791 |pmc=5927012 |doi= 10.1111/j.1349-7006.2002.tb01272.x |name-list-format=vanc| author2=Nishiu M  | author3=Tomita Y  | display-authors=3  | last4=Miwa  | first4=H  | last5=Takakuwa  | first5=T  | last6=Iuchi  | first6=K  | last7=Yamamoto  | first7=S  | last8=Aozasa  | first8=K  }}
*{{cite journal  | author=Fujiwara H |title=Clinical significance of serum neuron-specific enolase in patients with adult T-cell leukemia |journal=Am. J. Hematol. |volume=71 |issue= 2 |pages= 80–4 |year= 2002 |pmid= 12353304 |doi= 10.1002/ajh.10190  |name-list-format=vanc| author2=Arima N  | author3=Ohtsubo H  | display-authors=3  | last4=Matsumoto  | first4=Tadashi  | last5=Kukita  | first5=Toshimasa  | last6=Kawada  | first6=Hideaki  | last7=Imaizumi  | first7=Rie  | last8=Ozaki  | first8=Atsuo  | last9=Matsushita  | first9=Kakushi }}
*{{cite journal  | author=Fujiwara H |title=Clinical significance of serum neuron-specific enolase in patients with adult T-cell leukemia |journal=Am. J. Hematol. |volume=71 |issue= 2 |pages= 80–4 |year= 2002 |pmid= 12353304 |doi= 10.1002/ajh.10190  |name-list-format=vanc| author2=Arima N  | author3=Ohtsubo H  | display-authors=3  | last4=Matsumoto  | first4=Tadashi  | last5=Kukita  | first5=Toshimasa  | last6=Kawada  | first6=Hideaki  | last7=Imaizumi  | first7=Rie  | last8=Ozaki  | first8=Atsuo  | last9=Matsushita  | first9=Kakushi }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Rodríguez-Núñez A |title=Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis |journal=Brain Dev. |volume=25 |issue= 2 |pages= 102–6 |year= 2003 |pmid= 12581805 |doi=10.1016/S0387-7604(02)00160-2  |name-list-format=vanc| author2=Cid E  | author3=Rodríguez-García J  | display-authors=3  | last4=Camiña  | first4=F  | last5=Rodríguez-Segade  | first5=S  | last6=Castro-Gago  | first6=M  }}
*{{cite journal  | author=Rodríguez-Núñez A |title=Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis |journal=Brain Dev. |volume=25 |issue= 2 |pages= 102–6 |year= 2003 |pmid= 12581805 |doi=10.1016/S0387-7604(02)00160-2  |name-list-format=vanc| author2=Cid E  | author3=Rodríguez-García J  | display-authors=3  | last4=Camiña  | first4=F  | last5=Rodríguez-Segade  | first5=S  | last6=Castro-Gago  | first6=M  }}
*{{cite journal  | author=Muley T |title=Technical performance and diagnostic utility of the new Elecsys neuron-specific enolase enzyme immunoassay |journal=Clin. Chem. Lab. Med. |volume=41 |issue= 1 |pages= 95–103 |year= 2003 |pmid= 12636057 |doi=10.1515/CCLM.2003.017  |name-list-format=vanc| author2=Ebert W  | author3=Stieber P  | display-authors=3  | last4=Raith  | first4=Hannelore  | last5=Holdenrieder  | first5=Stefan  | last6=Nagel  | first6=Dorothea  | last7=Fürst  | first7=Heinrich  | last8=Roth  | first8=Hans-Jürgen  | last9=Luthe  | first9=Hilmar  }}
*{{cite journal  | author=Muley T |title=Technical performance and diagnostic utility of the new Elecsys neuron-specific enolase enzyme immunoassay |journal=Clin. Chem. Lab. Med. |volume=41 |issue= 1 |pages= 95–103 |year= 2003 |pmid= 12636057 |doi=10.1515/CCLM.2003.017  |name-list-format=vanc| author2=Ebert W  | author3=Stieber P  | display-authors=3  | last4=Raith  | first4=Hannelore  | last5=Holdenrieder  | first5=Stefan  | last6=Nagel  | first6=Dorothea  | last7=Fürst  | first7=Heinrich  | last8=Roth  | first8=Hans-Jürgen  | last9=Luthe  | first9=Hilmar  |url=https://epub.ub.uni-muenchen.de/17836/1/cclm.2003.017.pdf }}
{{refend}}
{{refend}}



Latest revision as of 03:27, 4 December 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Gamma-enolase, also known as enolase 2 (ENO2) or neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene.[1][2] Gamma-enolase is a phosphopyruvate hydratase.

Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.[1]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

[[File:
<imagemap> Image:WP534.png
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
<imagemap> Image:WP534.png
|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit]]
Glycolysis and Gluconeogenesis edit
  1. The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

Utility

File:Hemangioblastoma - nse - high mag.jpg
Neuron-specific enolase (NSE) immunostaining of a cerebellar hemangioblastoma.

Detection of NSE with antibodies can be used to identify neuronal cells and cells with neuroendocrine differentiation. NSE is produced by small cell carcinomas which are neuroendocrine in origin. NSE is therefore a useful tumor marker for lung cancer patients.[3]

References

  1. 1.0 1.1 "ENO2 enolase 2 (gamma, neuronal)". NCBI Entrez Gene database.
  2. Online Mendelian Inheritance in Man (OMIM) Enolase 2 -131360
  3. Clegg N, Ferguson C, True LD, Arnold H, Moorman A, Quinn JE, Vessella RL, Nelson PS (April 2003). "Molecular characterization of prostatic small-cell neuroendocrine carcinoma". Prostate. 55 (1): 55–64. doi:10.1002/pros.10217. PMID 12640661.

Further reading