Diabetic ketoacidosis causes: Difference between revisions

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==Overview==
==Overview==
Sugar which is the main source of energy for cells, need insulin to enter inside the cells. When the patient lack enough Insulin, sugar will not be able to enter inside the cell. This situation prompts the release of certain hormones that break down fat. The breakdown of fat produces ketones bodies. This process is triggered in the presence of any infection or illness.
Diabetic ketoacidosis (DKA) can be caused by a deficiency of [[insulin]] and an excess of [[glucagon]]. This process may be triggered by presence of any [[infection]], lack of adherence to [[insulin]] treatment by diabetics, illness, prescription or illicit drugs and any condition that puts the body under [[physiological]] stress.


== Causes ==
== Causes ==
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=== Common Causes ===
=== Common Causes ===
* Drugs:<ref name="pmid17604410">{{cite journal |vauthors=Ramaswamy K, Kozma CM, Nasrallah H |title=Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine |journal=Drug Saf |volume=30 |issue=7 |pages=589–99 |year=2007 |pmid=17604410 |doi= |url=}}</ref>
* Drugs:<ref name="pmid17604410">{{cite journal |vauthors=Ramaswamy K, Kozma CM, Nasrallah H |title=Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine |journal=Drug Saf |volume=30 |issue=7 |pages=589–99 |year=2007 |pmid=17604410 |doi= |url=}}</ref>
** Antipsychotic agents: clozapine, olanzapine, risperidone  
** [[Antipsychotic drugs|Antipsychotic agents]]  ([[clozapine]], [[olanzapine]], [[risperidone]])
** Illicit drugs (cocaine and alcohol)
** Illicit drugs ([[cocaine]] and [[alcohol]])
** Others: corticosteroids, glucagon, interferon, pentamidine, sympathomimetic agents (albuterol, dopamine, dobutamine, terbutaline, ritodrine, thiazide diuretics)
** [[Corticosteroids]]
** [[Glucagon]]
** [[Interferon]]
** [[Pentamidine]]
** [[Sympathomimetic agents]] ([[albuterol]], [[dopamine]], [[dobutamine]], [[terbutaline]], [[ritodrine]], [[thiazide diuretics]])


* Infections:
* [[Infections]]:
** Pneumonia
** [[Pneumonia]]
** Sepsis
** [[Sepsis]]
** Urinary tract infection
** [[Urinary tract infection]]


* Lack of insulin
* Lack of [[insulin]]
* Nonadherence to insulin treatment plans:  
* Nonadherence to [[insulin]] treatment plans:  
** Body image issues
** Body image issues
** Financial problems
** Financial problems
** Psychological factors
** [[Psychological]] factors


* Unrecognized symptoms of new-onset diabetes mellitus
* Unrecognized [[symptoms]] of new-onset [[diabetes mellitus]]


* Physiological stressors:
* [[Physiological]] stressors:
** Acromegaly
** [[Acromegaly]]
** Thrombosis
** [[Thrombosis]]
** Cerebrovascular accident
** [[Cerebrovascular accident]]
** Cushing disease
** [[Cushing's disease]]
** Hemochromatosis
** [[Hemochromatosis]]
** Myocardial infarction
** [[Myocardial infarction]]
** Pancreatitis
** [[Pancreatitis]]
** Pregnancy
** [[Pregnancy]]
** Psychological stress
** [[Psychological]] stress
** Shock/hypovolemia
** [[Shock (medical)|Shock]]/[[hypovolemia]]
** Trauma
** [[Trauma]]


==References==
==References==

Revision as of 18:02, 22 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Diabetic ketoacidosis (DKA) can be caused by a deficiency of insulin and an excess of glucagon. This process may be triggered by presence of any infection, lack of adherence to insulin treatment by diabetics, illness, prescription or illicit drugs and any condition that puts the body under physiological stress.

Causes

The following are the causes of diabetic ketoacidosis (DKA):

Common Causes

References

  1. Ramaswamy K, Kozma CM, Nasrallah H (2007). "Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine". Drug Saf. 30 (7): 589–99. PMID 17604410.

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