De Quervain's thyroiditis medical therapy: Difference between revisions
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{{CMG}}; {{AE}} {{MMF}} | {{CMG}}; {{AE}} {{MMF}} | ||
==Overview== | ==Overview== | ||
The mainstay of therapy for de Quervain's thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms. Corticosteroids are usually used in severely ill patients. | The mainstay of therapy for de Quervain's thyroiditis is [[aspirin]] or [[Non-steroidal anti-inflammatory drug|non-steroidal anti-inflammatory]] drugs for pain control. [[Beta adrenergic-blocking agents|Beta-adrenergic blockers]] are recommended for the patients who develop [[Thyrotoxicosis|thyrotoxic symptoms]]. [[Corticosteroids]] are usually used in severely ill patients. | ||
==Medical Therapy== | ==Medical Therapy== | ||
The drugs used in the treatment of De Quervain's thyroiditis are:<ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid3427792">{{cite journal |vauthors=Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K |title=Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis |journal=Clin. Endocrinol. (Oxf) |volume=27 |issue=3 |pages=339–44 |year=1987 |pmid=3427792 |doi= |url=}}</ref><ref name="pmid8257868">{{cite journal |vauthors=Volpé R |title=The management of subacute (DeQuervain's) thyroiditis |journal=Thyroid |volume=3 |issue=3 |pages=253–5 |year=1993 |pmid=8257868 |doi= |url=}}</ref> | The drugs used in the treatment of De Quervain's thyroiditis are:<ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid3427792">{{cite journal |vauthors=Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K |title=Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis |journal=Clin. Endocrinol. (Oxf) |volume=27 |issue=3 |pages=339–44 |year=1987 |pmid=3427792 |doi= |url=}}</ref><ref name="pmid8257868">{{cite journal |vauthors=Volpé R |title=The management of subacute (DeQuervain's) thyroiditis |journal=Thyroid |volume=3 |issue=3 |pages=253–5 |year=1993 |pmid=8257868 |doi= |url=}}</ref> | ||
#Asprin or NSAIDs: | #[[Asprin]] or [[NSAIDs]]: | ||
#*Aspirin and non-steroidal anti-inflammatory drugs are used for pain control. | #*Aspirin and non-steroidal anti-inflammatory drugs are used for pain control. | ||
#Beta adrenergic blockers: | #[[Beta-adrenergic blocker|Beta adrenergic blockers]]: | ||
#*Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms. | #*Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms. | ||
#Corticosteroids: | #[[Corticosteroids]]: | ||
#*Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours. | #*Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours. | ||
#Levothyroxine: | #[[Levothyroxine]]: | ||
#*It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state. | #*It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state. | ||
Drug Regimen: | Drug Regimen: | ||
*Naproxen 500 to 1000 mg per day in two divided doses | *[[Naproxen]] 500 to 1000 mg per day in two divided doses | ||
*Ibuprofen 1200 to 3200 mg per day in three or four divided doses | *[[Ibuprofen]] 1200 to 3200 mg per day in three or four divided doses | ||
*Prednisone 40 mg per day orally. | *[[Prednisone]] 40 mg per day orally. | ||
*[[Levothyroxine (oral)|Synthetic levothyroxine]] (L-T4) 1.6–1.8 μg/kg of body weight per day orally. | *[[Levothyroxine (oral)|Synthetic levothyroxine]] (L-T4) 1.6–1.8 μg/kg of body weight per day orally. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 16:22, 7 August 2017
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The mainstay of therapy for de Quervain's thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms. Corticosteroids are usually used in severely ill patients.
Medical Therapy
The drugs used in the treatment of De Quervain's thyroiditis are:[1][2][3]
- Asprin or NSAIDs:
- Aspirin and non-steroidal anti-inflammatory drugs are used for pain control.
- Beta adrenergic blockers:
- Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms.
- Corticosteroids:
- Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours.
- Levothyroxine:
- It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state.
Drug Regimen:
- Naproxen 500 to 1000 mg per day in two divided doses
- Ibuprofen 1200 to 3200 mg per day in three or four divided doses
- Prednisone 40 mg per day orally.
- Synthetic levothyroxine (L-T4) 1.6–1.8 μg/kg of body weight per day orally.
References
- ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K (1987). "Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis". Clin. Endocrinol. (Oxf). 27 (3): 339–44. PMID 3427792.
- ↑ Volpé R (1993). "The management of subacute (DeQuervain's) thyroiditis". Thyroid. 3 (3): 253–5. PMID 8257868.