Craniopharyngioma MRI: Difference between revisions

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==Overview==
==Overview==
The diagnostic evaluation of craniopharyngioma includes high-definition brain imaging. Brain MRI with and without contrast is the gold standard. Computed tomography (CT) scan is optional and may show some calcifications that can be seen in these tumors.  However CT is not specific enough as a standalone diagnostic test.
The diagnostic evaluation of craniopharyngioma includes high-definition brain imaging. Brain MRI with and without contrast is the gold standard. Computed tomography (CT) scan is optional and may show some calcifications that can be seen in these tumors.  However CT is not specific enough as a standalone diagnostic test. vascular imaging studies such as MR angiography (MRA) or CTA, is decided on a case-by-case basis typically for surgical planning or if a possible vascular malformation is spuspected.


==MRI==
==MRI==

Revision as of 20:36, 7 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

The diagnostic evaluation of craniopharyngioma includes high-definition brain imaging. Brain MRI with and without contrast is the gold standard. Computed tomography (CT) scan is optional and may show some calcifications that can be seen in these tumors. However CT is not specific enough as a standalone diagnostic test. vascular imaging studies such as MR angiography (MRA) or CTA, is decided on a case-by-case basis typically for surgical planning or if a possible vascular malformation is spuspected.

MRI

The MRI findings depend on the type of craniopharyngioma.[1]

Adamantinomatous

Adamantinomatous type is the most common form (90%), and typically have a lobulated contour as a result of usually multiple cystic lesions. Solid components are present, but usually form a relatively minor component of the mass, and enhance vividly on MRI scans. The calcification is very common (90%). These tumor have a predilection to be large, extending superiorly into the third ventricle, and encasing vessels, and even being adherent to adjacent structures. The findings on MRI are:

  • Cysts
    • Variable but 80% are mostly or partly T2 hyperintense
    • T1: iso- to hyperintense to brain (due to high protein content machinery oil cysts)
  • Solid component
    • T1 C+ (Gd): vivid enhancement
    • T2: variable or mixed
  • Calcification
  • Difficult to appreciate on conventional imaging
  • Susceptible sequences may better demonstrate calcification

MR angiography: It may demonstrate displacement of the A1 segment of the anterior cerebral artery (ACA).

MR spectroscopy: Cyst contents may show a broad lipid spectrum, with an otherwise flat baseline.

Papillary

Papillary craniopharyngioma tend to be more spherical in outline and usually lack the prominent cystic component; most are either solid or contain a few smaller cysts. Calcification is uncommon or even rare in the papillary subtype. These tumors tend to displace adjacent structures. The findings on MRI are:

  • Cysts
    • When present they are variable in signal
    • 85% T1 hypointense
  • Solid component
    • T1: iso- to lightly hypointense to brain
    • T1 C+: vivid enhancement
    • T2: variable/mixed

MR spectroscopy: Cyst contents does not show a broad lipid spectrum as they are filled with water fluid.

(Images courtesy of RadsWiki)

References

  1. MRI findings of Craniopharyngioma. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/craniopharyngioma


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