Churg-Strauss syndrome (patient information)

Revision as of 20:23, 12 April 2018 by Chandrakala Yannam (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Churg-Strauss syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Churg-Strauss syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Churg-Strauss syndrome (patient information) On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Churg-Strauss syndrome (patient information)

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Churg-Strauss syndrome (patient information)

CDC on Churg-Strauss syndrome (patient information)

Churg-Strauss syndrome (patient information) in the news

Blogs on Churg-Strauss syndrome (patient information)

Directions to Hospitals Treating Churg-Strauss syndrome

Risk calculators and risk factors for Churg-Strauss syndrome (patient information)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

Eosinophilic granulomatosis with polyangiitis previously called Churg-Strauss syndrome involves primarily small and medium sized blood vessels resulting in vessel inflammation. The exact cause of the disease is not known. However, various environmental factors, allergensgenetics, and drugs may play a role in triggering disease process by activating different types of white blood cells. The disease is characterized by the presence of asthma, hypereosinophiliarhinosinusitistingling and numbness of hands and feet (peripheral neuropathy) and multiple organ involvements including skinGI tract, and kidney.

What are the symptoms of Churg-Strauss syndrome

Symptoms of eosinophilic granulomatosis with polyangiitis typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable.[1]

What causes Churg-Strauss syndrome?

There are no established causes for eosinophilic granulomatosis with polyangiitis. However, various allergensinfectionsvaccinations and drugs may act as a triggering agents, and are responsible for developing disease. Genetics may also play a role.

Who is at highest risk?

Any one can develop eosinophilic granulomatosis with polyangiitis. Studies shown, it occurs mostly between 40-60 years with people having chronic history of asthma and allergic manifestations.

Diagnosis

Physical examination of lungs, heart, nervous system, skin and upper airway tract, along with the following tests can help in finding out eosinophilic granulomatosis with polyangiitis.

When to seek urgent medical care?

You should see the doctor if you experience any of the following:

The above symptoms may also present in association with other diseases, but they have to be evaluated properly by medical professional.

Treatment Options

Where to find medical care for Churg-Strauss syndrome

Directions to Hospitals Treating eosinophilic granulomatosis with polyangiitis

Prevention

Currently, there are no established preventive measures for eosinophilic granulomatosis with polyangiitis.

What to expect (Outlook/Prognosis)?

  • With treatment, the outlook for most patients is good.
  • Studies have shown that most people who receive and cyclophosphamide are doing much better. However, the disease relapses are common.

Possible Complications

Without treatment, eosinophilic granulomatosis with polyangiitis can result in the following complications. Complications depend on organ system involvement.

Sources

References

  1. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M (April 2015). "Churg-Strauss syndrome". Autoimmun Rev. 14 (4): 341–8. doi:10.1016/j.autrev.2014.12.004. PMID 25500434.

Template:WH Template:WS