Chronic cholecystitis laboratory findings: Difference between revisions
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Laboratory values may be notable for an elevated [[alkaline phosphatase]], possibly an elevated [[bilirubin]] (although this may indicate [[choledocholithiasis]]), and possibly an elevation of the [[WBC]]. [[CRP]] ([[C-reactive protein]]) is often elevated. The degree of elevation of these laboratory values may depend on the degree of inflammation of the [[gallbladder]]. Patients with acute cholecystitis are much more likely to manifest abnormal laboratory values, while in chronic cholecystitis the laboratory values are frequently normal. | Laboratory values may be notable for an elevated [[alkaline phosphatase]], possibly an elevated [[bilirubin]] (although this may indicate [[choledocholithiasis]]), and possibly an elevation of the [[WBC]]. [[CRP]] ([[C-reactive protein]]) is often elevated. The degree of elevation of these laboratory values may depend on the degree of inflammation of the [[gallbladder]]. Patients with acute cholecystitis are much more likely to manifest abnormal laboratory values, while in chronic cholecystitis the laboratory values are frequently normal. | ||
==Overview== | |||
Laboratory findings consistent with the diagnosis of chronic cholecystitis include [[leukocytosis]] and elevated [[CRP]]. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
* | *Laboratory findings consistent with the diagnosis of chronic cholecystitis include:<ref name="pmid1928982">{{cite journal |vauthors=Hafif A, Gutman M, Kaplan O, Winkler E, Rozin RR, Skornick Y |title=The management of acute cholecystitis in elderly patients |journal=Am Surg |volume=57 |issue=10 |pages=648–52 |year=1991 |pmid=1928982 |doi= |url=}}</ref><ref name="pmid8780469">{{cite journal |vauthors=Gruber PJ, Silverman RA, Gottesfeld S, Flaster E |title=Presence of fever and leukocytosis in acute cholecystitis |journal=Ann Emerg Med |volume=28 |issue=3 |pages=273–7 |year=1996 |pmid=8780469 |doi= |url=}}</ref><ref name="pmid24679431">{{cite journal |vauthors=Knab LM, Boller AM, Mahvi DM |title=Cholecystitis |journal=Surg. Clin. North Am. |volume=94 |issue=2 |pages=455–70 |year=2014 |pmid=24679431 |doi=10.1016/j.suc.2014.01.005 |url=}}</ref><ref name="urlGallbladder, Cholecystitis, Acute - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK459171/#article-19448.s5 |title=Gallbladder, Cholecystitis, Acute - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | ||
* | **[[Leukocytosis]] | ||
**Elevated [[CRP]] | |||
** | **Elevated [[Alkaline Phosphatase|alkaline phosphate]] | ||
** | **[[Hyperbilirubinemia]] | ||
** Mild elevation of pancreatic enzymes like [[amylase]], [[lipase]]. | ** Mild elevation of pancreatic enzymes like [[amylase]], [[lipase]]. | ||
Revision as of 18:06, 8 February 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
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Overview
Laboratory values may be notable for an elevated alkaline phosphatase, possibly an elevated bilirubin (although this may indicate choledocholithiasis), and possibly an elevation of the WBC. CRP (C-reactive protein) is often elevated. The degree of elevation of these laboratory values may depend on the degree of inflammation of the gallbladder. Patients with acute cholecystitis are much more likely to manifest abnormal laboratory values, while in chronic cholecystitis the laboratory values are frequently normal.
Overview
Laboratory findings consistent with the diagnosis of chronic cholecystitis include leukocytosis and elevated CRP.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of chronic cholecystitis include:[1][2][3][4]
- Leukocytosis
- Elevated CRP
- Elevated alkaline phosphate
- Hyperbilirubinemia
- Mild elevation of pancreatic enzymes like amylase, lipase.
References
- ↑ Hafif A, Gutman M, Kaplan O, Winkler E, Rozin RR, Skornick Y (1991). "The management of acute cholecystitis in elderly patients". Am Surg. 57 (10): 648–52. PMID 1928982.
- ↑ Gruber PJ, Silverman RA, Gottesfeld S, Flaster E (1996). "Presence of fever and leukocytosis in acute cholecystitis". Ann Emerg Med. 28 (3): 273–7. PMID 8780469.
- ↑ Knab LM, Boller AM, Mahvi DM (2014). "Cholecystitis". Surg. Clin. North Am. 94 (2): 455–70. doi:10.1016/j.suc.2014.01.005. PMID 24679431.
- ↑ "Gallbladder, Cholecystitis, Acute - StatPearls - NCBI Bookshelf".