Chancroid natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.

Overview

Natural History

  • The incubation period for H. ducreyi is typically 4 to 10 days, after which erythematous papules arise.[1]
  • Approximately 2 to 3 days after symptom onset, papules evolve into pustules.[2]
  • Pustules may resolve spontaneously or ulcerate in approximately 1-2 weeks since formation. Patients typically develop between 1-4 ulcers.
  • Inguinal lymphadenitis develops in approximately half of patients, more commonly in males than females.[3]

References

  1. Chancroid. UpToDate (September 25, 2015). http://www.uptodate.com/contents/chancroid#H3 Accessed January 19, 2016.
  2. Spinola, S. M. (2002). "Immunopathogenesis of Haemophilus ducreyi Infection (Chancroid)". Infection and Immunity. 70 (4): 1667–1676. doi:10.1128/IAI.70.4.1667-1676.2002. ISSN 0019-9567.
  3. Lewis, D A (2003). "Chancroid: clinical manifestations, diagnosis, and management". Sexually Transmitted Infections. 79 (1): 68–71. doi:10.1136/sti.79.1.68. ISSN 1368-4973.

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