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The characteristic lesion in chancroid is a painful, nonindurated [[ulcer]]. In men the most common site of this ulcer is the [[perpuce]] and in women the [[labia majora]].
The characteristic lesion in chancroid is a painful, nonindurated [[ulcer]]. In men the most common site of this ulcer is the [[perpuce]] and in women the [[labia majora]].


==Symptoms==  
==Symptoms==
After an incubation period of 4 to 10 days, chancroid begins with a small erythematous papules that develop into pustules that may ulcerate within several days to weeks. The ulcer characteristically:
The characteristic feature of chancroid is a genital lesion. A patient may present with either of the following types of lesions, depending on the stage of infection:
*Erythematous [[papules]]
*[[Boil|Pustules]]
*[[Ulcers]]
These manifestations are only local.


*Ranges in size dramatically from 3 to 50 mm (1/8 inch to two inches) across
Ulcer characteristics:
*Is painful
*Ranges in size from 3 to 50 mm (1/8 to 2 inches) in diameter
*Has sharply defined, undermined borders
*Painful
*Has irregular or ragged borders
*Soft, nonindurated
*Has a base that is covered with a gray or yellowish-gray material
*Irregular border
*Has a base that bleeds easily if traumatized or scraped
*Sharp margins
*Grey/yellow exudate


More specifically, the CDC's standard clinical definition for a probable case of chancroid includes all of the following:
Other symptoms include:
*Inguinal lymphadenitis in approximately 50% of patients, known as [[Bubo|buboes]] (typically unilateral and predominantly in males)
*[[Dysuria]] in females
*[[Dyspareunia]] in females


The CDC's standard clinical definition for a probable case of chancroid includes all of the following:
*Patient has one or more painful genital ulcers. The combination of a painful ulcer with tender adenopathy is suggestive of chancroid; the presence of suppurative adenopathy is almost pathognomonic.
*Patient has one or more painful genital ulcers. The combination of a painful ulcer with tender adenopathy is suggestive of chancroid; the presence of suppurative adenopathy is almost pathognomonic.
 
*No evidence of ''[[Treponema pallidum]]'' is indicated by dark-field examination of ulcer or by a serologic test for [[syphilis]] performed at least 7 days after the onset of ulcer.
*No evidence of ''[[Treponema pallidum]]'' is indicated by dark-field examination of ulcer or by a serologic test for [[Syphilis]] performed at least 7 days after the onset of ulcer.
*The clinical presentation is not typical of disease caused by [[Herpes Simplex Virus]] (HSV), or result of culture for HSV is negative.
 
*The clinical presentation is not typical of disease caused by [[human herpesvirus 2]] ([[Herpes Simplex Virus]]), or result of culture for HSV is negative.
 
About half of infected men have only a single ulcer. Women frequently have four or more ulcers, with fewer symptoms. The ulcers appear in specific locations, such as the coronal sulcus of the uncircumcised glans penis in men, or the fourchette and labia minora in women.
 
===Common locations in men (from most common to least common)===
*[[Foreskin]] (prepuce) (most common)
*Groove behind the head of the penis ([[coronal sulcus]])
*Shaft of the penis
*Head of the penis ([[glans penis]])
*Opening of the penis (urethral meatus)
*[[Scrotum]] (least common)
 
===Common locations in women===
In women the most common location for ulcers is the [[labia majora]]. "Kissing ulcers" may develop. These are ulcers that occur on opposing surfaces of the labia. Other areas such as the [[labia minora]], [[perineum|perineal]] area, and inner thighs may also be involved. The most common symptoms in women are pain with urination and pain with intercourse.
 
The initial ulcer may be mistaken as a "hard" [[chancre]], the typical sore of primary [[syphilis]], as opposed to the "soft chancre" of chancroid.
 
Approximately one third of the infected individuals will develop enlargements of the [[inguinal]] [[lymph nodes]], the nodes located in the fold between the leg and the lower abdomen.
 
Half of those who develop swelling of the inguinal lymph nodes will progress to a point where the nodes rupture through the skin producing draining abscesses. The swollen lymph nodes and abscesses are often referred to as buboes.


==References==
==References==

Revision as of 19:15, 21 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D. Nate Michalak, B.A. Serge Korjian M.D.

Overview

The characteristic lesion in chancroid is a painful, nonindurated ulcer. In men the most common site of this ulcer is the perpuce and in women the labia majora.

Symptoms

The characteristic feature of chancroid is a genital lesion. A patient may present with either of the following types of lesions, depending on the stage of infection:

These manifestations are only local.

Ulcer characteristics:

  • Ranges in size from 3 to 50 mm (1/8 to 2 inches) in diameter
  • Painful
  • Soft, nonindurated
  • Irregular border
  • Sharp margins
  • Grey/yellow exudate

Other symptoms include:

  • Inguinal lymphadenitis in approximately 50% of patients, known as buboes (typically unilateral and predominantly in males)
  • Dysuria in females
  • Dyspareunia in females

The CDC's standard clinical definition for a probable case of chancroid includes all of the following:

  • Patient has one or more painful genital ulcers. The combination of a painful ulcer with tender adenopathy is suggestive of chancroid; the presence of suppurative adenopathy is almost pathognomonic.
  • No evidence of Treponema pallidum is indicated by dark-field examination of ulcer or by a serologic test for syphilis performed at least 7 days after the onset of ulcer.
  • The clinical presentation is not typical of disease caused by Herpes Simplex Virus (HSV), or result of culture for HSV is negative.

References


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