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{{drugbox |
<div style="float: right;">
| IUPAC_name = (6''R'',7''R'')-3-(acetyloxymethyl)-7-[(2-cyanoacetyl)amino]-<br>8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-<br>carboxylic acid
[[File:Cefacetrile.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]</div>
| image = Cefacetrile.png  
 
| CAS_number = 10206-21-0
__NOTOC__
| ATC_prefix = J01
 
| ATC_suffix = DB10
| PubChem = 91562
| DrugBank =
| C = 13 | H = 13 | N = 3 | O = 6 | S = 1
| molecular_weight = 339.325 g/mol
| bioavailability =
| protein_bound = 23 to 38%
| metabolism =
| elimination_half-life = 1.2 hours
| excretion = [[Kidney|Renal]] (72%)
| pregnancy_AU =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US =  <!-- A / B  / C / D / X -->
| pregnancy_category = 
| legal_AU =  <!-- Unscheduled / S2 / S3 / S4  / S8 -->
| legal_CA =  <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK =  <!-- GSL / P / POM / CD / Class A, B, C -->
| legal_US =  <!-- OTC / Rx-only  / Schedule I, II, III, IV, V -->
| legal_status =
| routes_of_administration = [[Intravenous therapy|Intravenous]], [[Intramuscular injection|intramuscular]]
}}
{{SI}}
{{SI}}


{{CMG}}


'''Cefacetrile''' ([[International Nonproprietary Name|INN]], also spelled cephacetrile) is a [[Broad-spectrum antibiotic|broad-spectrum]] first generation [[cephalosporin]] [[antibiotic]] effective in [[Gram-positive]] and [[Gram-negative]] bacterial infections. It is a [[bacteriostatic]] antibiotic. Cefacetrile is marketed under the trade names '''Celospor''', '''Celtol''', and '''Cristacef'''.
==Overview==
'''Cefacetrile''' ([[International Nonproprietary Name|INN]], also spelled cephacetrile) is a [[Broad-spectrum antibiotic|broad-spectrum]] first generation [[cephalosporin]] [[antibiotic]] effective in [[gram-positive]] and [[gram-negative]] bacterial infections. It is a [[bacteriostatic]] antibiotic.<ref>{{cite web|url=http://www.emea.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500011465.pdf|publisher=[[European Medicines Agency]], Committee for Veterinary Medicinal Products|title=Cefacetrile Summary Report|year=1998}}</ref><ref name="AC">{{cite book|title=Austria-Codex|editor=Haberfeld, H|publisher=Österreichischer Apothekerverlag|location=Vienna|year=2007|edition=2007/2008|isbn=3-85200-183-8|language=German}}</ref> Cefacetrile is marketed under the trade names '''Celospor''', '''Celtol''', and '''Cristacef''',<ref>{{cite pmid|7206219}}</ref> and as '''Vetimast''' for the treatment of [[mammary]] infections in lactating cows.<ref name="AC" />
 
==References==
{{Reflist|2}}


{{CephalosporinAntiBiotics}}
{{CephalosporinAntiBiotics}}


[[Category:Cephalosporin antibiotics]]
[[Category:Cephalosporin antibiotics]]
 
[[Category:Carboxylate esters]]
 
[[Category:Drug]]
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Revision as of 15:47, 7 April 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. It is a bacteriostatic antibiotic.[1][2] Cefacetrile is marketed under the trade names Celospor, Celtol, and Cristacef,[3] and as Vetimast for the treatment of mammary infections in lactating cows.[2]

References

  1. ↑ "Cefacetrile Summary Report" (PDF). European Medicines Agency, Committee for Veterinary Medicinal Products. 1998.
  2. ↑ 2.0 2.1 Haberfeld, H, ed. (2007). Austria-Codex (in German) (2007/2008 ed.). Vienna: Österreichischer Apothekerverlag. ISBN 3-85200-183-8.
  3. ↑ PMID 7206219 (PMID 7206219)
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