Cardiology overview pharmacology: Difference between revisions
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* [[Pravastatin]] | * [[Pravastatin]] | ||
* [[Sildenafil]] (Viagra) | * [[Sildenafil]] (Viagra) | ||
==Drug Side Effects and Toxicity== | |||
* [[Protease inhibitors]] are associated with the development of [[myocardial infarction]] in patients with [[AIDS]]. | |||
==References== | ==References== |
Revision as of 17:29, 31 October 2011
Cardiology Overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Drug Drug Interactions
- Cyclosporin co-administration is associated with a higher rate of myositis among statin users as a result of inhibition of CYP3A4. The exception is pravastatin in which this is not a problem.
- Nitrate should not be given to patients who are taking Cialis or Viagra. if the patient has ingested Cialis, then you should wait 48 hours to administer nitrates. If the patient is ingested Viagra, you should wait 24 hours to administer nitrates.
Drug Food Interactions
Grapefruit
- Grapefruit juice inhibits the Cyp 3A4 enzyme which reduces the breakdown of drugs. Grapefruit juice also increases the p- glycoprotein in the intestines which increases drug absorption.
- Amiodarone
- Nifedipine
- Simvastatin
- Lovastatin
- Pravastatin
- Sildenafil (Viagra)
Drug Side Effects and Toxicity
- Protease inhibitors are associated with the development of myocardial infarction in patients with AIDS.