Cardiology overview pharmacology: Difference between revisions
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* [[Nifedipine]] | * [[Nifedipine]] | ||
* [[Simvastatin]] | * [[Simvastatin]] | ||
* [[Lovastatin]] | |||
* [[Pravastatin]] | |||
* [[Sildenafil]] (Viagra) | |||
==References== | ==References== |
Revision as of 17:26, 31 October 2011
Cardiology Overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Drug Drug Interactions
- Cyclosporin co-administration is associated with a higher rate of myositis among statin users as a result of inhibition of CYP3A4. The exception is pravastatin in which this is not a problem.
Drug Food Interactions
Grapefruit
- Grapefruit juice inhibits the Cyp 3A4 enzyme which reduces the breakdown of drugs. Grapefruit juice also increases the p- glycoprotein in the intestines which increases drug absorption.
- Amiodarone
- Nifedipine
- Simvastatin
- Lovastatin
- Pravastatin
- Sildenafil (Viagra)