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{{Breast lumps}}
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==Overview==
==Overview==


There is insufficient evidence to recommend routine screening for [disease/malignancy].
Screening for [[breast lumps]] is recommended by breast examination, [[ultrasound]], [[mammography]], [[magnetic resonance imaging]].
 
OR
 
According to the [guideline name], screening for [disease name] is not recommended.
 
OR
 
According to the [guideline name], screening for [disease name] by [test 1] is recommended every [duration] among patients with [condition 1], [condition 2], and [condition 3].
==Screening==
==Screening==
The Screening methods of [[breast lesions]]<ref name="pmid25114845">{{cite journal| author=Shah R, Rosso K, Nathanson SD| title=Pathogenesis, prevention, diagnosis and treatment of breast cancer. | journal=World J Clin Oncol | year= 2014 | volume= 5 | issue= 3 | pages= 283-98 | pmid=25114845 | doi=10.5306/wjco.v5.i3.283 | pmc=4127601 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25114845  }} </ref>:
The Screening methods of breast lesions:<ref name="pmid25114845">{{cite journal| author=Shah R, Rosso K, Nathanson SD| title=Pathogenesis, prevention, diagnosis and treatment of breast cancer. | journal=World J Clin Oncol | year= 2014 | volume= 5 | issue= 3 | pages= 283-98 | pmid=25114845 | doi=10.5306/wjco.v5.i3.283 | pmc=4127601 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25114845  }} </ref>
* [[Breast examination]]
* [[Breast examination]]
** [[Self breast examination]]
** Self breast examination
*** Although this is controversial, most clinicians recommend women to perform self examination monthly
*** Although this is controversial, most clinicians recommend women to perform self examination monthly.
**[[Clinical breast examination]]
**Clinical breast examination
*** Women with age> 40 years is recommended for clinical breast examination annually
*** Women with age> 40 years is recommended to have clinical breast examination, annually.
* [[Ultrasound]]
* [[Ultrasound]]
** whole breast ultrasound detects lesions in dense breast tissue which could not be diagnosed by mammography <ref name="pmid19727744">{{cite journal| author=Kelly KM, Dean J, Comulada WS, Lee SJ| title=Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts. | journal=Eur Radiol | year= 2010 | volume= 20 | issue= 3 | pages= 734-42 | pmid=19727744 | doi=10.1007/s00330-009-1588-y | pmc=2822222 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19727744  }} </ref>
** Whole breast [[ultrasound]] detects lesions in dense breast tissue which could not be diagnosed by [[mammography]].<ref name="pmid19727744">{{cite journal| author=Kelly KM, Dean J, Comulada WS, Lee SJ| title=Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts. | journal=Eur Radiol | year= 2010 | volume= 20 | issue= 3 | pages= 734-42 | pmid=19727744 | doi=10.1007/s00330-009-1588-y | pmc=2822222 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19727744  }} </ref>
*[[Mammography]]
*[[Mammography]]<ref name="pmid15282350">{{cite journal| author=Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM et al.| title=Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. | journal=N Engl J Med | year= 2004 | volume= 351 | issue= 5 | pages= 427-37 | pmid=15282350 | doi=10.1056/NEJMoa031759 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15282350  }}  [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=15656564 Review in: ACP J Club. 2005 Jan-Feb;142(1):23] </ref>
**Gold standard of screening
**[[Gold standard (test)|Gold standard test]] of screening
**Early detection of non-palpabale masses
**Early detection of non-palpabale masses
**Regarding to 2013 NCCN guidelines annual screening in average risk women aged≥ 40 years
**According to 2013 NCCN guidelines
**Regarding to 2013 NCCN guidelines annual screening in high risk women from age of 25 years
***Annual screening in average risk women aged ≥ 40 years
**Sensitivity of 0.33-0.39 and specificity of 0.95  
***Annual screening in high risk women from age of 25 years
*[[Magnetic resonance imaging]]
**[[Sensitivity]] of 0.33-0.39 and [[specificity]] of 0.95  
**Significant method for detection, assessment and management of breast cancer
*[[Magnetic resonance imaging]]<ref name="pmid15282350">{{cite journal| author=Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM et al.| title=Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. | journal=N Engl J Med | year= 2004 | volume= 351 | issue= 5 | pages= 427-37 | pmid=15282350 | doi=10.1056/NEJMoa031759 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15282350  }}  [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=15656564 Review in: ACP J Club. 2005 Jan-Feb;142(1):23] </ref><ref name="pmid18458280">{{cite journal| author=Warner E, Messersmith H, Causer P, Eisen A, Shumak R, Plewes D| title=Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer. | journal=Ann Intern Med | year= 2008 | volume= 148 | issue= 9 | pages= 671-9 | pmid=18458280 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18458280  }} </ref>
**Sensitivity of 0.77-0.79 and specificity of 0.86-0.89
**Significant method for detection, assessment, and management of [[breast cancer]]
** Based on 2013 NCCN guidelines annual MRI for individuals with > 20% risk of developing breast cancer in lifetime starting at age of 25 years
**[[Sensitivity]] of 0.77-0.79 and [[specificity]] of 0.86-0.89
** Beneficial modality in high risk individuals
** According on 2013 NCCN guidelines
** Valuable in individuals with equivocal results from other screening tests
*** Annual [[MRI]] for individuals with > 20% risk of developing [[breast cancer]] in lifetime starting at age of 25 years
**Usable for individuals with ineffective mammography results due to breast augmentation
** Beneficial modality for screening in high risk individuals
** Valuable screening method in individuals with equivocal results from other screening tests
**Usable for individuals with ineffective [[mammography]] results due to breast augmentation


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


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Latest revision as of 20:42, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Screening for breast lumps is recommended by breast examination, ultrasound, mammography, magnetic resonance imaging.

Screening

The Screening methods of breast lesions:[1]

  • Breast examination
    • Self breast examination
      • Although this is controversial, most clinicians recommend women to perform self examination monthly.
    • Clinical breast examination
      • Women with age> 40 years is recommended to have clinical breast examination, annually.
  • Ultrasound
  • Mammography[3]
    • Gold standard test of screening
    • Early detection of non-palpabale masses
    • According to 2013 NCCN guidelines
      • Annual screening in average risk women aged ≥ 40 years
      • Annual screening in high risk women from age of 25 years
    • Sensitivity of 0.33-0.39 and specificity of 0.95
  • Magnetic resonance imaging[3][4]
    • Significant method for detection, assessment, and management of breast cancer
    • Sensitivity of 0.77-0.79 and specificity of 0.86-0.89
    • According on 2013 NCCN guidelines
      • Annual MRI for individuals with > 20% risk of developing breast cancer in lifetime starting at age of 25 years
    • Beneficial modality for screening in high risk individuals
    • Valuable screening method in individuals with equivocal results from other screening tests
    • Usable for individuals with ineffective mammography results due to breast augmentation

References

  1. Shah R, Rosso K, Nathanson SD (2014). "Pathogenesis, prevention, diagnosis and treatment of breast cancer". World J Clin Oncol. 5 (3): 283–98. doi:10.5306/wjco.v5.i3.283. PMC 4127601. PMID 25114845.
  2. Kelly KM, Dean J, Comulada WS, Lee SJ (2010). "Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts". Eur Radiol. 20 (3): 734–42. doi:10.1007/s00330-009-1588-y. PMC 2822222. PMID 19727744.
  3. 3.0 3.1 Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM; et al. (2004). "Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition". N Engl J Med. 351 (5): 427–37. doi:10.1056/NEJMoa031759. PMID 15282350. Review in: ACP J Club. 2005 Jan-Feb;142(1):23
  4. Warner E, Messersmith H, Causer P, Eisen A, Shumak R, Plewes D (2008). "Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer". Ann Intern Med. 148 (9): 671–9. PMID 18458280.


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