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==Overview==
==Overview==


* '''Bleeding''' occurring spontaneously without injury, or bleeding that does not stop (with direct pressure) is abnormal.
'''Bleeding''' occurring spontaneously without injury, or bleeding that does not stop (with direct pressure) is abnormal.
==Classification==
Abnormal bleeding can be classified into the following groups:
Abnormal bleeding can be classified into the following groups:
# [[Coagulation factor]] disorders
# [[Coagulation factor]] disorders
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# Vascular disorders
# Vascular disorders


== Differential Diagnosis ==
== Causes ==


In alphabetical order. <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>
In alphabetical order. <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>
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* Complete physical examination including rectal exam and joint exam ([[hemarthrosis]])
* Complete physical examination including rectal exam and joint exam ([[hemarthrosis]])


== Laboratory Findings ==  
=== Laboratory Findings ===  
* [[Complete blood count]] ([[CBC]]) with [[peripheral smear]]
* [[Complete blood count]] ([[CBC]]) with [[peripheral smear]]
* [[Partial thromboplastin time]] ([[PTT]])
* [[Partial thromboplastin time]] ([[PTT]])
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* [[Corticosteroids]] ([[ITP]], [[HSP]])
* [[Corticosteroids]] ([[ITP]], [[HSP]])
* [[Tranexamic acid]] ([[liver disease]])
* [[Tranexamic acid]] ([[liver disease]])
====Contraindicated medications====
{{MedCondContrAbs|MedCond = Active pathological bleeding|Dabigatran|Dalteparin|Desirudin}}


=== Surgery and Device Based Therapy ===  
=== Surgery and Device Based Therapy ===  
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== References ==
== References ==
{{reflist|2}}
{{reflist|2}}
== Acknowledgements ==
The content on this page was first contributed by {{CMG}}
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Latest revision as of 05:19, 15 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bleeding occurring spontaneously without injury, or bleeding that does not stop (with direct pressure) is abnormal.

Classification

Abnormal bleeding can be classified into the following groups:

  1. Coagulation factor disorders
  2. Platelet disorders
  3. Vascular disorders

Causes

In alphabetical order. [1] [2]

Diagnosis

History and Symptoms

  • Complete history
    • Family history
    • Minor trauma bleeding
    • Tooth extractions
    • Postsurgical bleeding
    • Medications
    • Menorrhagia

Physical Examination

  • Complete physical examination including rectal exam and joint exam (hemarthrosis)

Laboratory Findings

Other Diagnostic Studies

Treatment

Acute Pharmacotherapies

Contraindicated medications

Active pathological bleeding is considered an absolute contraindication to the use of the following medications:

Surgery and Device Based Therapy

References

  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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